Presentation
Since no other symptoms are present, it is probably more worthwhile to look at symptoms that will NOT be present with carotenemia. [healthhype.com]
Hypercarotenemia, especially when present in girls or young women, can be an important clue to the diagnosis of. . . [nejm.org]
Longitudinal studies indicated that serum carotenoid levels declined while vitamin A levels were maintained. α-Carotenes and β-carotenes were not detected in the feces of hypercarotenemics but were present in non-hypercarotenemics. [unboundmedicine.com]
Hypercarotenemia was present in 4/21 girls with anorexia nervosa compared with 0/17 females with bulimia nervosa (p = 0.11). Transaminitis was present in 38.5% (AST) and 7.7% (ALT) of eating disorder patients. [ncbi.nlm.nih.gov]
Childhood hyperlipoproteinemia Type I IIA IIB III IV V Origin exogene endogene exogene Age of onset childhood childhood adult adult adult adult Familiary character present present Transmission autosomal recesive autosomal recesive Tryglycerides +++ normal [romj.org]
Entire Body System
- Anorexia
METHODS: Serum carotene was measured in 46 female adolescents between 13 years and 18 years of age (21 anorexia nervosa, 17 bulimia nervosa, 8 unclassified eating disorders). [ncbi.nlm.nih.gov]
[…] of vegetables, as in the case described by the authors, should increase the suspicion that the patient may have anorexia nervosa. [nejm.org]
Seven of the nine females had a thyroidal disorder, four of the 9 females suffered from anorexia nervosa, and five of the 9 females had amenorrhea. [ci.nii.ac.jp]
- Weight Loss
Mobilization of lipid stores and catabolic changes occurring with weight-loss states appear to be related in some undefined way to the elevated carotene levels. [ncbi.nlm.nih.gov]
loss R635Abnormal weight gain R636Underweight R638Other symptoms and signs concerning food and fluid intake R7301Impaired fasting glucose R7302Impaired glucose tolerance (oral) R7309Other abnormal glucose R739Hyperglycemia, unspecified R824Acetonuria [cms.gov]
I knew (somewhere deep down) that this wasn’t healthy, knew when I ran into people who had not seen me in awhile, who commented on my weight loss, that even though I said, “I have a lot more to go,” that I didn’t have more to go. I couldn’t stop. [biggreenpen.com]
PCV2 associated infections may include symptoms such as weight loss or failure to grow, enlarged lymph nodes, difficulty breathing, diarrhoea, pale skin and jaundice (yellowing of the skin). [context.reverso.net]
- Pain
Call your doctor if you have symptoms such as loss of appetite, stomach pain, or jaundice (yellowing of the skin or eyes). [context.reverso.net]
Sensation of loose, painful teeth Click Here for the Correct Answer Answer: B. [toxikonconsortium.org]
The patient reported having no nausea, vomiting, abdominal pain or change in the colour of her urine or stool. [cmaj.ca]
Besides this sign, symptoms of jaundice include nausea, vomiting, itching, pain in the belly, dark urine (pee), and pale feces (poop). The itching is caused by bilirubin being deposited in the skin. [medfriendly.com]
- Myxedema
The vast majority (90% to 95%) of cases of myxedema occur in primary hypothyroidism. [clinicaladvisor.com]
[…] called "Canary Girls"--due to "nitro groups" within the TNT that reacted with melanin in the workers' skin (2008 paper in the Chemical Educator Journal); Sorafenib-Sunitinib are two drugs with known adverse reaction of yellow skin discoloration [4]; Myxedema [romj.org]
- Fever
It made me worry, I thought she got yellow illness, but after that I saw her eye, the eyes not yellow, also the color of her feces not changes, she also don't have fever. So, I was thinking this is something different. [nurhafsah.blogspot.com]
While using octreotide, call your doctor if you have severe stomach pain, fever, bloating, nausea and vomiting, or jaundice (yellowing of the skin or eyes). [context.reverso.net]
Gastrointestinal
- Overeating
I am now a Lifetime member of Weight Watchers, which I have followed on and off over the years. I am about fourteen pounds over my goal weight right now, but I do understand that you can successfully lose weight nutritiously and healthfully. [biggreenpen.com]
Columbia University's Health Services department point out that an intake of over 20 mg of beta carotene, is enough to set off hypercarotenemia [4]. Hypercarotenemia can sometimes be an indicator of anorexia nervosa [4]. [romj.org]
Characteristic findings on physical examination Generalized myxedema is a manifestation of severe hypothyroidism developing over an extended period of time causing skin that appears waxy, doughy, swollen (although non-pitting) and dry. [clinicaladvisor.com]
Página 451 - Secular increases in relative weight and adiposity among children over two decades: the Bogalusa Heart Study. Pediatrics 1997 ;99: 420-426. Página 167 - AM, Kris-Etherton PM. [books.google.es]
It’s basically when your skin turns yellow because of an excess of carotene due to over-consumption of foods high in beta-carotene. It’s more common in vegans and vegetarians because foods highest in beta-carotene are mostly fruits and vegetables. [slendergrapefruit.wordpress.com]
- Nausea
While using octreotide, call your doctor if you have severe stomach pain, fever, bloating, nausea and vomiting, or jaundice (yellowing of the skin or eyes). [context.reverso.net]
The patient reported having no nausea, vomiting, abdominal pain or change in the colour of her urine or stool. [cmaj.ca]
Symptoms include headache, abdominal pain, nausea, vomiting, diarrhea, peri-oral and peripheral paresthesias, dizziness, palpitations, and diffuse flushing of the skin. References: Lawrence DT et al. Food Poisoning. [toxikonconsortium.org]
Enlarged liver and/or spleen Nausea, vomiting or diarrhea Carotenemia Pictures Palms Picture from Dermatology Atlas courtesy of Samuel Freire da Silva, M.D. Hands Picture from Dermatology Atlas courtesy of Samuel Freire da Silva, M.D. [healthhype.com]
Besides this sign, symptoms of jaundice include nausea, vomiting, itching, pain in the belly, dark urine (pee), and pale feces (poop). The itching is caused by bilirubin being deposited in the skin. [medfriendly.com]
- Vomiting
Symptoms include headache, abdominal pain, nausea, vomiting, diarrhea, peri-oral and peripheral paresthesias, dizziness, palpitations, and diffuse flushing of the skin. References: Lawrence DT et al. Food Poisoning. [toxikonconsortium.org]
The patient reported having no nausea, vomiting, abdominal pain or change in the colour of her urine or stool. [cmaj.ca]
Enlarged liver and/or spleen Nausea, vomiting or diarrhea Carotenemia Pictures Palms Picture from Dermatology Atlas courtesy of Samuel Freire da Silva, M.D. Hands Picture from Dermatology Atlas courtesy of Samuel Freire da Silva, M.D. [healthhype.com]
While using octreotide, call your doctor if you have severe stomach pain, fever, bloating, nausea and vomiting, or jaundice (yellowing of the skin or eyes). [context.reverso.net]
Besides this sign, symptoms of jaundice include nausea, vomiting, itching, pain in the belly, dark urine (pee), and pale feces (poop). The itching is caused by bilirubin being deposited in the skin. [medfriendly.com]
- Loss of Appetite
Call your doctor if you have symptoms such as loss of appetite, stomach pain, or jaundice (yellowing of the skin or eyes). [context.reverso.net]
She also reported alopecia, irritability, asthenia, and loss of appetite. She had no vision changes or gastrointestinal symptoms. Liver damage was ruled out, and the vitamin A dose was reduced to 50,000 IU every other day. [elsevier.es]
The initial symptoms include mental and physical sluggishness, constipation, loss of appetite, hoarseness in voice, leg cramps, cold intolerance, and unexplained weight gain. [clinicaladvisor.com]
- Failure to Thrive
[…] in childhood R627Adult failure to thrive R630Anorexia R631Polydipsia R632Polyphagia R633Feeding difficulties R634Abnormal weight loss R635Abnormal weight gain R636Underweight R638Other symptoms and signs concerning food and fluid intake R7301Impaired [cms.gov]
Liver, Gall & Pancreas
- Jaundice
Carotenemia and Jaundice Carotenemia should not be confused with jaundice which is yellowish discoloration of the skin mainly associated with liver and gallbladder disease. [healthhype.com]
Neonatal jaundice is relatively normal; bruises turn yellow when they heal; malaria, hepatitis, hemolytic anemia, pancreatic cancer and cirrhosis are serious causes of jaundice. [symptomscausestreatmentprevention.blogspot.com]
He or she may also develop newborn jaundice (yellowing of the skin). Jaundice is yellowing of the skin caused by too much bilirubin in the blood. [context.reverso.net]
WHAT ARE THE DIFFERENT TYPES OF JAUNDICE AND CAUSES OF JAUNDICE? There are many different types and causes of jaundice, described below, beginning with hemolytic jaundice. [medfriendly.com]
Figure 1 A 23-year-old woman who was admitted for jaundice was found to have yellow-orange discoloration of her skin (her hand is shown on the right, and the hand of a subject without hypercarotenemia is shown on the left). [nejm.org]
- Scleral Icterus
Hypercarotenemia is easily distinguished from jaundice because the whites of the eye (sclera) remain white, while people with true jaundice caused by liver problems have yellow sclera (scleral icterus). [naturallysavvy.com]
Note: Hypercarotinemia, as opposed to hyperbilirubinemia, does not result in scleral icterus. [toxikonconsortium.org]
Musculoskeletal
- Osteoporosis
[…] collagen disease 甲状腺機能亢進症 hyperthyroidism 甲状腺機能低下症 hypothyroidism 甲状腺中毒症 thyrotoxicosis 後天性免疫不全症候群 acquired immune deficiency syndrome 高コレステロール血症 hypercholesterolemia 高トリグリセリド血症 hypertriglyceridemia 高リポ蛋白血症 hyperlipoproteinemia ゴーシェ病 Gaucher disease 骨粗鬆症 osteoporosis [jsge.or.jp]
Skin
- Skin Discoloration
Hereditary hypercarotenemia and vitamin A deficiency is an extremely rare metabolic disorder characterized clinically by skin discoloration, elevated levels of carotene and low levels of vitamin A described in fewer than 5 patients to date. [monarchinitiative.org]
discoloration, elevated levels of carotene and low levels of vitamin A described in fewer than 5 patients to date. [orpha.net]
[…] the blood usually associated with a yellow discoloration of the skin. hy·per·car·o·te·ne·mi·a ( hīpĕr-kārŏ-tĕ-nēmē-ă ) Disorder marked by orange skin discoloration caused by excess carotenoids in the blood, usually from overconsumption of vegetables that [medical-dictionary.thefreedictionary.com]
- Yellow Discoloration of the Skin
[…] reacted with melanin in the workers' skin (2008 paper in the Chemical Educator Journal); Sorafenib-Sunitinib are two drugs with known adverse reaction of yellow skin discoloration [4]; Myxedema also can be associated with yellow skin and but not limited [romj.org]
[…] the blood usually associated with a yellow discoloration of the skin. hy·per·car·o·te·ne·mi·a ( hīpĕr-kārŏ-tĕ-nēmē-ă ) Disorder marked by orange skin discoloration caused by excess carotenoids in the blood, usually from overconsumption of vegetables that [medical-dictionary.thefreedictionary.com]
Carotene can cause a discoloration of the skin when present in large amounts within the body. This discoloration is typically yellow and sometimes even slightly orange in color. [healthhype.com]
What Are The Causes Of Yellow Feet And Hands: How To Get Rid Of It? Skin discoloration can be quite disconcerting if you do not understand the cause for it. [symptomscausestreatmentprevention.blogspot.com]
- Cutaneous Manifestation
“Cutaneous manifestations of thyroid disease”. J Am Acad Dermatol. vol. 25. 1992. pp. 885 (Discusses the many manifestations of thyroid disease that one can see in the skin.) Rashtak, S, Pittelkow, MR. “Skin involvement of autoimmune diseases”. [clinicaladvisor.com]
A study on the cutaneous manifestations of diabetes mellitus. Our Dermatol Online 2012; 3(2): 83-86. (doi: 10.7241/ourd.20122.17 ) Forman L. [romj.org]
- Pruritus
At physical examination a yellowish pigmentation on the palms and soles was observed, no hyperkeratosis, no erythema, and no excoriations due to pruritus (which was not declared by the child or other member of the family). [romj.org]
Neurologic
- Stupor
Kelley, our teacher, saying “let’s just go to the science fair” because it was useless trying to talk business machines while we were all in a shocked stupor. Debbie had had a cerebral hemorrhage. [biggreenpen.com]
Urogenital
- Amenorrhea
Abstract Six patients are described with hypothalamic amenorrhea and associated hypercarotenemia. The commencement of the hypothalamic amenorrhea followed weight reduction or stress in each case. [ncbi.nlm.nih.gov]
Seven of the nine females had a thyroidal disorder, four of the 9 females suffered from anorexia nervosa, and five of the 9 females had amenorrhea. [ci.nii.ac.jp]
Amenorrhea may be associated with carotenemia. This occurs in patients who consume a pure or predominantly vegetarian diet without red meat. Dietary modifications can reduce carotene levels, which, in turn, normalize the menstrual cycle. [emedicine.medscape.com]
Treatment
In addition to thorough extended discussion and coverage of all assessment and treatment topics encompassed by the third edition of the American Psychiatric Association's "Practice Guideline for the Treatment of Patients with Eating Disorders," the book [books.google.com]
Treatment Options Treatment of underlying hypothyroidism is essential with levothyroxine. [clinicaladvisor.com]
Treatment [ edit ] Carotenemia and carotenoderma is in itself harmless, and does not require treatment. In primary carotenoderma, when the use of high quantities of carotene is discontinued the skin color will return to normal. [en.wikipedia.org]
Prognosis
In heterozigot forms the survival is longer (about 30 years) and prognosis better. The polygenic forms have a moderate course and a good response to diet [9]. [romj.org]
[…] may be markedly elevated in patients with chronic glomerulonephritis and nephrotic syndrome Inborn errors of metabolism - Carotenemia may result from a failure to convert carotene into vitamin A due to an inborn error of metabolism Familial conditions Prognosis [emedicine.medscape.com]
Etiology
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
They are organised into groups, and further divided into clinical, etiological or histopathological sub-types. [orpha.net]
Etiology Pathophysiology The pathogenesis of this disease is due to low levels of thyroid hormone, especially free T3 and T4. [clinicaladvisor.com]
Even if the etiological factor is benign, and the discoloration responds quickly to medications, yellow discoloration indicates that some process or a certain substance may be burdening the body. [symptomscausestreatmentprevention.blogspot.com]
Etiology Dietary sources Diet-induced carotenemia is observed most frequently in infants and young children. [4] Mothers may induce the condition by giving their infants large amounts of carrots in commercial infant food preparations. [5] In addition, [emedicine.medscape.com]
Pathophysiology
Pathophysiology The normal color of the C S F is clear and colorless. The color appearance depends upon the presence of hyperbilirubinemia, hypercarotenemia, melanoma and elevated protein level. [labpedia.net]
However, the pathophysiology of hypercarotenemia is not yet fully understood. Moreover, differences in the amount of subcutaneous adipose tissue (SAT) in AN patients with the same BMI have been observed recently. [press.mu-varna.bg]
Etiology Pathophysiology The pathogenesis of this disease is due to low levels of thyroid hormone, especially free T3 and T4. [clinicaladvisor.com]
Carotinemia was originally noted as xanthosis diabetica in 1904 by von Noorden, who observed it to be prominent in the nasolabial folds and on the palms and soles. [2] Pathophysiology Carotenoids are pigments of plant origin and are responsible for the [emedicine.medscape.com]
Prevention
A deficiency after bariatric surgery. 8 However, different recommendations have been issued to prevent and treat vitamin A deficiency. [elsevier.es]
Collaborative Meta-Analysis of Randomised Trials of Antiplatelet Therapy for Prevention of Death, Myocardial Infarction, and Stroke in High Risk Patients. [books.google.es]
Author Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, Rutgers New Jersey Medical School; Visiting Professor, Rutgers University School of Public [emedicine.medscape.com]
It is important to have bilirubin levels checked regularly if jaundice is occurring so as to prevent significant problems from occurring. [medfriendly.com]