The disease is characterized by many of the symptoms of chronic anemia (fatigue, pale skin, and shortness of breath) as well as susceptibility to infection, jaundice and other eye problems, delayed growth, and episodic crises of severe pain in the abdomen [britannica.com]

Common symptoms of microcytic anemias include: fatigue, weakness, and tiredness loss of stamina shortness of breath dizziness pale skin If you experience any of these symptoms and they don’t resolve within two weeks, make an appointment to see your doctor [healthline.com]

When it comes to minimal macrocytosis with only marginally increased MCV, one must also consider alcohol-induced anemia and, particularly, hyper-regenerative hemolytic anemia, because the reticulocytes are substantially larger than normal erythrocytes [degruyter.com]