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Hyperglobulinemic Purpura

Hyperglobulinemic Purpuras


Presentation

  • Waldenström hyperglobulinemic purpura Other names Purpura hyperglobulinemica Specialty Dermatology Waldenström hyperglobulinemic purpura is a skin condition that presents with episodic showers of petechiae (small red or purple spots) occurring on all[en.wikipedia.org]
  • These cases were summarized recently by Taylor and Battle. 3 Since 1953 occasional new cases have been presented by authors in Europe. 4 , 5 This report describes what appears to be the second case of hyperglobulinemic purpura in the United States.Case[nejm.org]
  • Improve your interpretation of presenting symptoms with 41 new topics and 7 new references in the Differential Diagnosis section.[books.google.com]
Chronic Fatigue Syndrome
  • High frequency of autoantibodies to insoluble cellular antigens in patients with chronic fatigue syndrome. Arthritis Rheum 1997; 40:295. 9. Vitali , C, Bombardieri, S, Jonsson , R, et al.[dry.org]
Infertility
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Easy Bruising
  • Lesions of colloid milium may become purpuric after trauma.27 FEMALE EASY-BRUISING SYNDROME The female predominance and the frequent association with phases of the menstrual cycle suggest that the female easy-bruising syndrome (purpura simplex) is due[medtextfree.wordpress.com]
  • bruising and spontaneous bleeding from the small vessels. [43] Frequently, the bleeding is mainly in the skin, causing petechiae, ecchymoses or both and in some cases there is bleeding also from the mucous membrane. [43] Vascular defect of hemostasis[ijdr.in]
Sore Throat
  • Throat, Urinary Retention, Valvular Heart Disease and Vegetative State.[books.google.com]
Failure to Thrive
  • Fred Ferri’s popular "5 books in 1" format provides quick guidance on menorrhagia, Failure to Thrive (FTT), Cogan’s syndrome, and much more.[books.google.com]
Tachycardia
  • Ferri s popular "5 books in 1" format provides quick guidance on vitamin-D deficiency, statin-induced muscle syndrome, postural tachycardia syndrome (POTS), and much more.[books.google.com]
  • 325mg qd Nifedipine 10mg TID Pentoxifylline 400mg BID-TID 20 21 22 Marshall-White Syndrome “Bier’s Spots” Marbled mottling produced in the forearm and hand with use of a tight sphgmomanometer Consist of Bier’s spot and is associated with insomnia and tachycardia[slideplayer.com]
Back Pain
  • Improve your interpretation of presenting symptoms with 97 new topics in the Differential Diagnosis section including Amnionic Fluid Alpha-Fetoprotein Elevation, Back Pain, Bone Mass, Calcifications, Delirium, Gastric Dilation, Heart Failure, Muscle Disease[books.google.com]
Purpura
  • Secondary hyperglobulinemic purpura of Waldenström is characterized by polyclonal gammopathy associated mainly with autoimmune diseases. Its occurrence with multiple myeloma is very rare.[ncbi.nlm.nih.gov]
  • 8833011 Sjogren's syndrome with paraproteinemia and hyperglobulinemic purpura.[eurekamag.com]
  • […] of Waldenstrom Hyperglobulinemic Purpura Hyperglobulinemic Purpura of Waldenström Waldenstrom Hyperglobulinemic Purpura Hyperglobulinemic Purpura, Waldenstrom Hyperglobulinemic Purpuras Purpura, Waldenstrom Hyperglobulinemic Purpuras, Hyperglobulinemic[decs.bvs.br]
  • purpura in HLA identical sisters. ( 6437921 ) Ciriello M.M....Ascari E. 1984 8 SjAPgren,'s syndrome and benign hyperglobulinemic purpura of Waldenstrom. ( 7325506 ) Lu L.W....Katzman B. 1981 9 Hyperglobulinemic purpura in the course of multiple myeloma[malacards.org]
Petechiae
  • Waldenström hyperglobulinemic purpura Other names Purpura hyperglobulinemica Specialty Dermatology Waldenström hyperglobulinemic purpura is a skin condition that presents with episodic showers of petechiae (small red or purple spots) occurring on all[en.wikipedia.org]
  • Blood spots under the skin may be either purpura or petechiae. CD36 deficiency may be a cause of post transfusion purpura. People with Henoch's purpura are not affected by joint disease.[diki.pl]
  • Rumpel-Leede sign: distal shower of petechiae that occurs immediately after the release of pressure from a tourniquet release. Associated with capillary fragility.[slideplayer.com]
  • Hypergammaglobulinemic purpura of Waldenstrom is characterized by recurrent episodes of petechiae, hypergammaglobulinemia, an elevated erythrocyte sedimentati. Waldenstrom hypergammaglobulinemic purpura and pregnancy.[jezzbag.ovil.info]
  • Thus, it is common for the first signs of petechiae due to thrombocytopenia to appear at the ankles.[medtextfree.wordpress.com]
Skin Discoloration
  • PruritusExamination & warning presentation Examination :  Patient general condition  Characteristic of the skin lesion e.g. o Burrows of scabies o Lichenification of eczema o Skin discoloration o Scaly lesion Warning presentation :  No overt skin disease[de.slideshare.net]
Anxiety Disorder
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Amnesia
  • Features 30 all-new topics, including Zika virus, hepatitis E, asthma-COPD overlap syndrome, drug-induced parenchymal lung disease, binge eating disorder, hereditary breast and ovarian cancer syndrome, transient global amnesia, and more.[books.google.com]
Neuralgia
  • Diseases and Disorders section features more than 300 new figures and tables, as well as 20 new topics including: cyclic vomiting syndrome, traveler’s diarrhea, chronic pruritus, post-herpetic neuralgia, enteropathic arthritis, and hoarding disorder.[books.google.com]

Workup

Treatment

  • Broaden your knowledge with updated information on serological diagnosis of pemphigus, TNF-I for hidradenitis suppurativa, the use of immunosuppressives for atopic dermatitis, excimer laser for the treatment of vitiligo and much more.[books.google.com]
  • 1 Mycophenolate mofetil treatment of a patient with hyperglobulinemic purpura. ( 15455483 ) 2004 2 Therapeutic effect of ethamsylate in a case of hyperglobulinemic purpura associated with Sjogren's syndrome. ( 8833011 ) Casas H.A. 1996 3 Benign hyperglobulinemic[malacards.org]

Prognosis

  • The exocrine manifestations, diagnosis, treatment, and prognosis of both sicca and extraglandular manifestations are discussed separately.[uptodate.com]
  • The prognosis of SBN is severe; however, some authors have reported prolonged complete remission [ 8 , 10 – 12 ]. 4. Conclusion BNS is a rare and potentially treatable complication of WM.[hindawi.com]
  • E-selectin: High concentrations in patient sera correlate with low incidence of metastasis and, consequently, correlate with good prognosis. Expression of elevated E-selectin facilitates metastasis.[clinicaladvisor.com]
  • Prognosis: Survival is slightly better than in polyarteritis nodosa, with up to 90% of patients alive 1 year after the diagnosis. BIBLIOGRAPHY Gay RM, Ball GV. Vasculitis. In: Koopman WJ, ed.[rheumaknowledgy.com]

Etiology

  • English : BL blood CF cerebrospinal fluid CI chemically induced CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology[decs.bvs.br]
  • Etiology: This systemic vasculitis is of uncertain etiology.[rheumaknowledgy.com]
  • Williams Dermatology Service, Veterans Administration Medical Center, and Departments of Dermatology and Pediatrics, University of California School of Medicine, San Francisco Abstract Seborrheic dermatitis is a common skin condition of infancy of unknown etiology[pedsinreview.aappublications.org]
  • Etiology Cryoglobulinemias are associated with a variety of illnesses (listed below), three most common categories being: infections, autoimmune disorders, and malignancies.[clinicaladvisor.com]
  • McKee's Pathology of the Skin is the most complete, in-depth resource on dermatopathology, covering etiology, pathogenesis, disease mechanisms, and recent genetic, molecular, and basic science data. Drs. J.[books.google.de]

Epidemiology

  • Allowable Qualifiers English : BL blood CF cerebrospinal fluid CI chemically induced CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology[decs.bvs.br]
  • Aim: To study the epidemiology, etiological, host and environmental factors, clinical manifestations, its variations, and the type prevalent in this part of the world.[idoj.in]
  • Epidemiology Waldenström macroglobulinemia is a relatively rare condition, with the 1500 cases diagnosed per year in the United States accounting for approximately 2% of hematologic malignancies.[emedicine.medscape.com]
  • We review the literature on BNS and discuss its epidemiology, presentation, diagnosis, treatment, and prognosis. 2. Case Presentation A 57-year-old man, heavy smoker, was treated since November 2003 for a WM.[hindawi.com]
  • Dry eyes or mouth--an epidemiological study in Swedish adults, with special reference to primary Sjogren's syndrome. J Autoimmun 1989; 2:521. 12. Vitali, C, Bombardieri , S, Moutsopoulos, HM, et al.[dry.org]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology of circulating immune complexes. Arthritis Rheum, 1982, 125, 783–787. Google Scholar 13. Clark, R.A., Abraham, G.N., Kyle, R., Vaughan, J.H. Gammaglobulin complexes in rheumatoid arthritis and hypergammaglobulinemic purpura.[link.springer.com]
  • […] caused by organisms growing in vessel and vessel walls (usually immunocompromised host) o Vessel-invasive fungus ( Mucor, Aspergillus, Cephalosporium, Rhizopus, etc.) o Ecthyma gangrenosum ( Pseudomonas ) o Disseminated strongyloidiasis · Uncertain pathophysiology[dermaamin.com]
  • The volume describes the pathophysiology of the condition, diagnostic strategies and tools, and current and emerging therapeutic options, focusing on direct clinical applications for busy healthcare professionals.[books.google.de]
  • (See Pathophysiology, Etiology, and Workup.)[emedicine.medscape.com]
  • Idiopathic thrombocytopenic purpura pathophysiology and management. Int J Hematol 2002; 76 (Suppl 2 ): 123-31. ].[benthamopen.com]

Prevention

  • Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets[books.google.com]
  • […] diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology GE genetics HI history IM immunology ME metabolism MI microbiology MO mortality NU nursing PS parasitology PA pathology PP physiopathology PC prevention[decs.bvs.br]

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