Patient continued to have galactorrhea, and prolactin level rose for two years without any apparent identified cause, except breast implantation surgery. [ncbi.nlm.nih.gov]

They typically present with oligomenorrhea, amenorrhea, galactorrhea, or infertility. Galactorrhea is less common in postmenopausal women due to lack of estrogen. [emedicine.com]

A 38-year-old white female patient seeks medical attention complaining of weight gain (Body mass index: 35) associated with anxiety. She started sibutramine treatment and presented with amenogalactorrhea. [ncbi.nlm.nih.gov]

The principal concern for endocrinologists with the newer drugs has been the metabolic effects of weight gain, glucose intolerance, hyperlipidemia, and hypertension [ 2 ]. [ijpeonline.biomedcentral.com]

Moreover, hyperprolactinemia has been linked to weight gain and insulin resistance, which can be ameliorated following medical treatment. [link.springer.com]

Moreover, as majority of population were females, the clinical features in the macroprolactinemia group as compared to true hyperprolactinemic group were mostly related to non-pituitary causes like drug intake [42.5% (54) vs. 37% (30)], heat intolerance [ncbi.nlm.nih.gov]

Symptoms In men, hyperprolactinemia may be associated with decreased libido, impotence, visual disturbances, gynecomastia (breast development) or reduced beard growth. [myfertility.ca]

In women it is usually associated with galactorrhea and secondary amenorrhea; in men it may be a factor in gynecomastia, decreased libido, and impotence. [medical-dictionary.thefreedictionary.com]

Clinical presentation of hyperprolactinemia (2) Men          Decreased libido Impotence – unresponsive to testosterone treatment Decreased sperm production Infertility Gynecomastia Rarely galactorrhea Decreased muscle mass Body hair Osteoporosis [slideshare.net]

In males, symptoms include decreased libido, erectile dysfunction, other signs of hypogonadism, and local symptoms from an expanding pituitary tumor. [touchendocrinology.com]

Indications for men: Perform a lab test for prolactin for men with hypogonadism, gynecomastia, galactorrhoea, decreased libido and erectile dysfunction. [urology-textbook.com]

A 20-year-old man presented to a local physician because of a milky nipple discharge of 2 months' duration. He was otherwise healthy. Findings on physical examination were unremarkable except for the milky discharge from both nipples on expression. [ncbi.nlm.nih.gov]

She denies hirsutism and acne but admits to thin milky nipple discharge upon squeezing (but not spontaneous). [mdedge.com]

Nipple discharge Rule out breast pathology (by history, physical examination, mammography) Galactorrhea 11. Step 1. Galactorrhea Evaluation for breast tumor     Unilateral Single duct Bloody or Serosanguineous Associated with breast mass 12. [slideshare.net]

The day before her next injection, the patient complained of nipple discharge and breast tenderness, leading to a check of her prolactin level. [healio.com]

There are, however, gender-specific symptoms… Symptoms of Hyperprolactinemia For Women : irregular nipple discharge breast milk production in the absence of pregnancy (Galactorrhea) irregular menstrual cycles including amenorrhea (absent period) and luteal [natural-fertility-info.com]

We present two cases. (1) A 35-year-old woman suffering from chronic tension-type headache interspersed with occasional episodes of migraine without aura (as defined by the International Headache Society criteria). [ncbi.nlm.nih.gov]

After 6 months, however, she complained of persistent frontal headache and a repeat MRI revealed that the adenoma had increased in size to 16 mm. The patient was referred to an endocrinologist for further evaluation. [ncbi.nlm.nih.gov]

Frequency United States This condition occurs in less than 1% of the general population and in 5-14% of patients presenting with secondary amenorrhea. [3] Approximately 75% of patients presenting with galactorrhea and amenorrhea have hyperprolactinemia [emedicine.com]

Amenorrhea was the most common presenting symptom (49.5%) followed by galactorrhea (44.3%). Median initial serum prolactin level was 117 ng/mL (25.1-1,624 ng/mL). [ncbi.nlm.nih.gov]

In women it is usually associated with galactorrhea and secondary amenorrhea; in men it may be a factor in gynecomastia, decreased libido, and impotence. [medical-dictionary.thefreedictionary.com]

J Hum Reprod Sci 2010;3:111-2 Amenorrhea with infertility has long been challenging to the treating physician. A high prolactin level is encountered in about one- third of women with no obvious cause of amenorrhea. [dx.doi.org]

One month later, she had oligomenorrhea and galactorrhea. We ruled out all causes of hyperprolactinemia. [ncbi.nlm.nih.gov]

Serum prolactin level, menstrual disturbances, sexual dysfunction, psychopathologies, and quality of life were measured at weeks 0, 1, 2, 4, 6, and 8. [ncbi.nlm.nih.gov]

dysfunction and found no difference between men and women in the prevalence of sexual dysfunction in such cases. [7] A study by Ishioka et al indicated that in men receiving antipsychotic agents, a link exists between hyperprolactinemia and an increase [emedicine.com]

Frequency United States This condition occurs in less than 1% of the general population and in 5-14% of patients presenting with secondary amenorrhea. [3] Approximately 75% of patients presenting with galactorrhea and amenorrhea have hyperprolactinemia [emedicine.com]

In women it is usually associated with galactorrhea and secondary amenorrhea; in men it may be a factor in gynecomastia, decreased libido, and impotence. [medical-dictionary.thefreedictionary.com]

Methods: We retrospectively evaluated our outpatient admission records for PCOS, hirsutism, oligomenorrhea, or secondary amenorrhea. PCOS diagnosis was made after excluding other causes of hirsutismus and in accordance with Rotterdam criteria. [endocrine-abstracts.org]

dryness When occurring in men, the symptoms typically involve sexual dysfunction and/or pain associated with the formation of the prolactinoma. [pcos.about.com]

In women: cessation of menstrual periods (amenorrhea), decreased menstrual flow (oligomenorrhea), abnormal production of breast milk when not breastfeeding (galactorrhea), excess facial hair (hirsutism), vaginal dryness and pain during intercourse and [healthcommunities.com]

In addition, women may have: Vaginal dryness, leading to pain during intercourse Problems with menstruation—having no periods or irregular periods Production of breast milk when not pregnant or nursing Men may also have: Erectile dysfunction—trouble getting [hormone.org]

The level of Prolactin increases in the Blood than the normal level. This leads to Hyperlactation, Menstrual Problems and Galactorrhea. [herbpathy.com]

In a limited number of cases where prolactin increase is caused by pituitary tumors larger than 10 mm that do not improve with drugs, the possibility of performing a surgery or radiation treatment must be evaluated. [ingenes.com]

Kruger TH et al have demonstrated that sexual intercourse with orgasm induced not only the well-established immediate prolactin increasing of 300% but also an additional prolactin elevation around noon of the next day. [intechopen.com]