Presentation
Abstract A 13-month-old boy presented with acute onset of complete atrioventricular block and wide complex tachycardia but normal hemodynamics. [ncbi.nlm.nih.gov]
Case Presentation: We present a case of a 59 year old male with tetanus of the generalized type with an unusual presenting complaint of heart failure, preceding the classic muscle spasms associated with tetanus infection. [herdin.ph]
In this case report we present an atypical clinical presentation of hypersensitivity eosinophilic myocarditis, presenting mostly as a respiratory infection with flu-like symptoms with an abnormally high eosinophil count. [link.springer.com]
Entire Body System
- Pathologist
[…] this Atlas is to contribute to the knowledge of morphological findings of the main cardiovascular diseases among the various specialists who deal with people affected of heart diseases: cardiologists and cardiovascular surgeons, clinical and forensic pathologists [books.google.com]
More frequently, the pathologist sees incidental hypersensitivity myocarditis at autopsy or in an explant from an asymptomatic patient. [emedicine.medscape.com]
Lorie R. and Hager WD et al documented that infective endocarditis was the most common pattern underlying neutrophilic myocarditis. [8,9] The clinicians and the pathologists should keep in mind that in young male patients presenting with chest pain and [ispub.com]
Cardiovascular
- Heart Disease
Now, in full color, this leading reference offers you everything you need to treat and manage pediatric heart conditions. A comprehensive and exhaustive reference of fundamental and clinical aspects of heart disease in infancy and childhood. [books.google.com]
diseases I51.81 Takotsubo syndrome I51.89 Other ill-defined heart diseases I51.9 Heart disease, unspecified I52 Other heart disorders in diseases classified elsewhere I60 Nontraumatic subarachnoid hemorrhage I60.0 Nontraumatic subarachnoid hemorrhage [icd10data.com]
It may also disguise itself as ischemic, valvular, or hypertensive heart disease. [medical-dictionary.thefreedictionary.com]
- Cardiomegaly
CXR: Normal cardiac silhouette but pericarditis or overt clinical congestive heart failure is associated with cardiomegaly. Vascular redistribution. Interstitial and alveolar oedema. Pleural effusion. [patient.info]
The chest radiograph is variable, ranging from normal to cardiomegaly with or without pulmonary vascular congestion and edema. [textbookofcardiology.org]
Her pulse was weak and thready, and she had an enlarged, tender liver, cardiomegaly, and S 3 and S 4 gallops. [nejm.org]
[…] should always be considered in the differential diagnosis of children who present with a viral prodrome and nonspecific respiratory or abdominal symptoms associated with tachycardia, hypotension, or cardiac rhythm abnormalities, even in the absence of cardiomegaly [ahcmedia.com]
Diagnostic Modalities The chest x-ray typically demonstrates cardiomegaly and increased pulmonary vascular markings, indicating pulmonary oedema. [jpma.org.pk]
- Systolic Murmur
She had a systolic murmur at the apex. Her chest auscultation was normal. Abdominal examination was unremarkable. [pmj.bmj.com]
Systolic murmurs of mitral regurgitation and tricuspid regurgitation may be present in patients with ventricular enlargement. Sudden cardiac death due to a fatal arrhythmia is sometimes the presenting feature. [merckmanuals.com]
[心]収縮[期] systolic function収縮機能 systolic murmur (SM)収縮期雑音 t tachycardia 頻拍(脈) tachypnea呼吸頻数、頻呼吸 technetium (Tc)テクネシ(チ)ウム temporal resolution時間分解能 terminal portion終末部 tetralogy of Fallot (T/F, TOF) ファロー四徴[症] thallium (Tl)タリウム thoracic aorta 胸[部]大動脈 thoractomy [tokyo-med.ac.jp]
Workup
X-Ray
- Cardiomegaly on Chest X-ray
[…] on chest x-ray." 20 Diagnostic Evaluation Electrocardiogram (ECG). [ahcmedia.com]
Microbiology
- Human Parvovirus B19
Lupescu A, Bock CT, Lang PA et al. (2006) Phospholipase A2 activity-dependent stimulation of Ca2+ entry by human parvovirus B19 capsid protein VP1. J Virol 80: 11370–11380 PubMed CrossRef Google Scholar 27. [link.springer.com]
More recently, new molecular techniques have revealed that the most commonly detected viral agents were Parvovirus B19 and human herpesvirus type 6 [ 12, 13, 14 ]. [mdpi.com]
T Wave
- T Wave Inversion
Physical agents Electric shock Hyperpyrexia Radiation/radiotherapy Investigations ECG: changes may include ST-segment elevation/depression, T-wave inversion, atrial arrhythmias, transient atrioventricular (AV) block. [patient.info]
Markers of myocardial damage ( troponin or creatine kinase cardiac isoenzymes) are elevated. [10] The ECG findings most commonly seen in myocarditis are diffuse T wave inversions; saddle-shaped ST-segment elevations may be present (these are also seen [en.wikipedia.org]
Treatment
Early recognition, instrumental diagnosis, and related specific treatment made this patient's course favorable. [the-medical-dictionary.com]
Treatment While myocarditis is a serious condition, there is no medical treatment necessary if it results from a general viral infection. The only steps to recovery include rest and avoidance of physical exertion. [medical-dictionary.thefreedictionary.com]
Emphasizes the treatment of corrected congenital heart disease for coverage of the clinical management of cardiac problems in the adolescent and young adult. [books.google.com]
Endomyocardial biopsy was performed in order to establish or exclude a clear-cut relationship between cardiac dysfunction and clozapine, and was crucial to establish a correct diagnosis and appropriate treatment. [ncbi.nlm.nih.gov]
Prognosis
However, whether HSM at the time of HTx affects long-term prognosis, including acute cellular rejection (ACR) and antibody-mediated rejection (AMR), after HTx remains unclear. [ncbi.nlm.nih.gov]
On the clinical side they discuss the diagnosis, prognosis, and treatment of nonspecific and specific myocarditis in separate chapters devoted to such major idiopathic clinical entities as cardiac sarcoidosis, giant cell myocarditis, eosinophilic myocarditis [books.google.com]
In amyloidosis and hypertrophic cardiomyopathy, myocarditis may affect prognosis. [textbookofcardiology.org]
Complications Congestive cardiac failure Pulmonary oedema Cardiogenic shock Dilated cardiomyopathy Dysrhythmias Recurrent myositis Prognosis The prognosis for patients with acute myocarditis can be very good but depends on clinical presentation, LVEF [patient.info]
The overall prognosis of the disease is good with survival rates up to 80%. Keywords: Myocarditis, Paediatric population, PubMed. [jpma.org.pk]
Etiology
Each chapter includes eight to ten gross and microscopic photographs with legends highlighting the pathologic features of the disease, as well as succinct text covering etiology, clinical aspects, and differential diagnosis. [books.google.com]
Antiviral therapy has not been shown to be helpful in the treatment of viral etiologies. Bacterial etiologies may be treated with antibiotics, but this has not been shown to be effective except possibly in the acute infectious phase. [merckmanuals.com]
Table 1 reviews the various infectious and non-infectious etiologies of myocarditis. Pathophysiology The pathogenesis of myocarditis is poorly understood due to the complex nature of the disease and its various etiologies ( see Figure 2 ). [ahcmedia.com]
How can infectious etiologies be tested for on autopsy? A: In general, the heart looks pretty normal in patients with myocarditis by the naked eye. [myocarditisfoundation.org]
[…] has been suggested for GCM, based on the antimyosin GCM Lewis rat model and a high prevalence of associated autoimmune disorders, especially inflammatory bowel disease Diagrams / tables Images hosted on other servers: Etiology of Myocarditis Clinical [pathologyoutlines.com]
Epidemiology
Grist NR, Reid D (1993) Epidemiology of viral infections of the heart. In: Banatvala JE (ed) Viral infections of the heart. Arnold, London, pp 23–31 Google Scholar 13. [link.springer.com]
[…] eosinophilic and giant cell myocarditis (GCM) Terminology GCM has been termed idiopathic GCM, pernicious myocarditis, Fiedler myocarditis, acute idiopathic interstitial myocarditis, giant cell granulomatous myocarditis, and granulomatous myocarditis Epidemiology [pathologyoutlines.com]
Epidemiology The exact incidence of myocarditis is unknown. One study suggested that myocarditis is the cause of sudden cardiac death in 8.6% of cases and is identified in up to 9% of routine post-mortem examinations [ 1 ]. [patient.info]
[…] catecholamine-induced injury and reperfusion injury) Pathologic classification is complicated, however, because tissue biopsies often are not obtained, and a presumptive clinical diagnosis must sometimes be confirmed by means of indirect methods such as serology. [1] Epidemiology [emedicine.medscape.com]
Epidemiological context This case was the only one found in a series of 1141 autopsies performed during one year (2011) in a Medico-Legal Institution that serves a territorial area of 29.206 Km 2 with a population of 2.595.540 inhabitants. [omicsonline.org]
Pathophysiology
This entity can also complicate Churg-Strauss syndrome and seems to share the same pathophysiology with type I variant of Kounis syndrome. [nursingcenter.com]
[…] myocarditis, Fiedler myocarditis, acute idiopathic interstitial myocarditis, giant cell granulomatous myocarditis, and granulomatous myocarditis Epidemiology Incidence difficult to determine as most cases are believed to be subclinical or underdiagnosed Pathophysiology [pathologyoutlines.com]
The suggested pathophysiological mechanisms need to be further evaluated and verified on a large cohort of patients. [journals.plos.org]
The pathophysiology of myocarditis remains a subject of research. [merckmanuals.com]
In this review article we present two cases of eosinophilic myocarditis and outline the current scientific literature on this topic including its pathophysiology, diagnosis, and recommended therapy. [bmcresnotes.biomedcentral.com]
Prevention
Prevention Although myocarditis is an unpredictable disease, the following measures may help prevent its onset. Individuals should: Take extra measures to avoid infections, and obtain appropriate treatment for infections. [medical-dictionary.thefreedictionary.com]
Página 487 - Diphtheria, tetanus, and pertussis: recommendations for vaccine use and other preventive measures. Recommendations of the Immunization Practices Advisory Committee (ACIP). [books.google.es]
Survival after heart transplantation is not impaired, and postoperative steroid therapy may prevent EM. [journals.lww.com]
[…] and Atkins KA described that in developed countries infectious causes of heart muscle inflammation are uncommon in immunocompetent individuals. [3] Patients with Acquired immunodeficiency syndrome ( AIDS ), transplant associated immunosupression to prevent [ispub.com]
How can drug hypersensitivity syndrome be prevented? Patients who develop drug hypersensitivity syndrome must avoid taking the causative medicine/s again. [dermnetnz.org]