We report a patient with polysomnography findings related to hypersomnia, as a primary presenting symptom, who was shown to have stereotypical gelastic seizures. [ncbi.nlm.nih.gov]

The symptoms most commonly present during adolescence or early adulthood, although an individual can develop symptoms of hypersomnia at any age. [news-medical.net]

The Diagnostic and Statistical Manual of Mental Disorders, which presents the guidelines used by the American Psychiatric Association for diagnosis of disorders, states that symptoms must be present for at least a month, and must interfere with a person's [minddisorders.com]

• Hypersomnia

  This review details most of those disorders, including narcolepsy with and without cataplexy, idiopathic hypersomnia with and without long sleep time, recurrent hypersomnia, behaviorally induced insufficient sleep syndrome, hypersomnia due to medical [ncbi.nlm.nih.gov]

  Convert to ICD-10-CM : 780.54 converts approximately to: 2015/16 ICD-10-CM G47.10 Hypersomnia, unspecified Approximate Synonyms Daytime hypersomnia Hypersomnia Hypersomnia (excessive sleeping) Hypersomnia, daytime Hypersomnia, idiopathic Idiopathic hypersomnia [icd9data.com]

  Let's Get #BeyondSleepy Welcome to the Hypersomnia Foundation, committed to improving the lives of people living with idiopathic hypersomnia (IH) and related sleep disorders. [hypersomniafoundation.org]

  ISCD-3 Central Disorders of Hypersomnolence (Open Table in a new window) Primary Secondary Narcolepsy type 1 (NT1) Narcolepsy type 2 (NT2) Hypersomnia due to a medical condition Hypersomnia due to a psychiatric condition Idiopathic hypersomnia (IH) Hypersomnia [emedicine.com]

• Fatigue

  The only symptom is excessive fatigue. Secondary hypersomnia is due to other medical conditions. These can include sleep apnea, Parkinson’s disease, kidney failure, and chronic fatigue syndrome. [healthline.com]

  Excessive daytime sleepiness (EDS) is much more than being fatigued or tired. [tuck.com]

• Whipple Disease

  Hypersomnia in Whipple disease: case report Hipersónia na doença de Whipple: relato de caso Luís F. [scielo.br]

  Whipple disease (WD) is a rare systemic infection caused by Tropheryma whippelii. Neurological involvement has been recognised in 40% of patients, either as initial manifestations or during the course of the disease. [ncbi.nlm.nih.gov]

  Hypersomnia can also develop within months after viral infections such as Whipple's disease, mononucleosis, HIV, and Guillain–Barré syndrome.[9] Behaviorally induced insufficient sleep syndrome must also be considered in the differential diagnosis of [en.wikipedia.org]

• Varicella-Zoster Virus Infection

  A variant of the Kleine-Levin syndrome precipitated by both Epstein-Barr and varicella-zoster virus infections. Biol Psychiatry. 1993 Mar 1. 33 (5):388-90. [Medline]. GALLINEK A. [emedicine.medscape.com]

• Dysostosis

  Abstract Polysomnography and blood gas measurements during sleep in a young man with craniofacial dysostosis, who presented with an extremely severe sleep apnea syndrome, are reported. [ncbi.nlm.nih.gov]

• Kayser-Fleischer Ring

  Kayser-Fleischer ring was not detectable. D-penicillamine (DPA) was introduced. At 8-10 months after the initiation of the therapy the patient's complaints gradually resolved. [ncbi.nlm.nih.gov]

• Guillain-Barré Syndrome

  Subgroup II: This group includes patients who had a viral infection associated with neurologic symptoms, such as Guillain-Barré syndrome, infectious mononucleosis, or atypical viral pneumonia. [elaine-moore.com]

  Subgroup II This group includes patients who had a viral infection associated with neurologic symptoms, such as Guillain-Barré syndrome, infectious mononucleosis, or atypical viral pneumonia. [emedicine.com]

• Gliosis

  Severe neuronal loss and gliosis were observed in the midbrain and pontine raphe, particularly in dorsal raphe nucleus and superior central nucleus. Pontine and medullary reticular formation also showed a marked cell loss and fibrillary gliosis. [ncbi.nlm.nih.gov]

• White Matter Lesions

  A CT study found hyperostosis and corresponding microcephaly in 71% and ventriculomegaly in 13% of patients.9 However, using MRI, ventriculomegaly was evident in 71%.10 Studies with MRI are conflicting with respect to the presence of white matter lesions [jnnp.bmj.com]

• HLA-DR1

  Both patients share the same HLA haplotype (HLA-DR1, DQ1) which has been found in Kleine-Levin syndrome. [ncbi.nlm.nih.gov]

Type and frequency of substance use were assessed at treatment entry. Substance use was also assessed 12 months following treatment completion. [ncbi.nlm.nih.gov]

[…] access to treatment with pitolisant while a U.S. [mayo.edu]

The attacks usually continue indefinitely. x Prognosis The prognosis for persons with hypersomnia depends on the cause of the disorder. [ninds.nih.gov]

Prognosis The prognosis for persons with hypersomnia depends on the cause of the disorder. While the disorder itself is not life threatening, it can have serious consequences, such as automobile accidents caused by falling asleep while driving. [brainfacts.org]

Prognosis Hypersomnia can be chronic, especially when not associated with another disorder and therefore can continue to worsen if left untreated. Treatments are readily available and can improve the prognosis significantly. [allpsych.com]

What is the Prognosis of Idiopathic Hypersomnia? (Outcomes/Resolutions) The prognosis of Idiopathic Hypersomnia depends upon the severity of the symptoms. [dovemed.com]

[…] the etiology or severity of centrally mediated hypersomnia. [ncbi.nlm.nih.gov]

Narcolepsy: The narcolepsy is with unknown etiology. Single inheritance cases are described, but there is often no occurrence in the family. [differencebetween.net]

Articles were included if they were in English and included information regarding the epidemiology, diagnosis, pathophysiology, or treatment of IH or HD. [ncbi.nlm.nih.gov]

Epidemiology of narcolepsy : development of the Ullanlinna Narcolepsy Scale / Christer Hublin -- 14. Epidemiology of narcolepsy / Maurice M. Ohayon -- 15. [worldcat.org]

Summary Epidemiology The prevalence is unknown but has been estimated at 1/10,000 - 1/25,000 for the first form and 1/11,000 to 1/100,000 for the second one. Both forms start before the age of 25 years old and affect both sexes equally. [orpha.net]

Articles were included if they were in English and included information regarding the epidemiology, diagnosis, pathophysiology, or treatment of IH or HD. [ncbi.nlm.nih.gov]

Article highlights Little is known about the pathophysiology, clinical characterization and treatment response of IH. Due to insufficient level of evidences, no treatment has currently an indication for the treatment of EDS in IH. [tandfonline.com]

Canine narcolepsy : history and pathophysiology / Emmanuel Mignot -- 24. Vigilance tests in narcolepsy / Johannes Mathis and Christian W. Hess -- 25. Lessons from sleepy mice : narcolepsy-cataplexy and the orexin neuropeptide system / Jon T. [worldcat.org]

Thus, this case suggests that vitamin B12 may be effective for preventing recurrent hypersomnia. [ncbi.nlm.nih.gov]

If all these treatments are not helpful then the last resort is surgery to prevent blockage of airways while sleeping. [epainassist.com]

Physicians should give an attention to the sleep symptoms to prevent the delay in the diagnosis and effective intervention. [e-jsm.org]

@article{89dcbb2027d846b78036d83b83aa7021, title = "Prevention of hypermenorrhea with leuprolide in premenopausal women undergoing bone marrow transplantation", abstract = "We report on the use of leuprolide to prevent heavy menstrual bleeding that often [ucdavis.pure.elsevier.com]

Primary hypersomnias such as idiopathic hypersomnia and narcolepsy may not be preventable. [sleepopolis.com]