Presentation
We report a patient with polysomnography findings related to hypersomnia, as a primary presenting symptom, who was shown to have stereotypical gelastic seizures. [ncbi.nlm.nih.gov]
Entire Body System
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Hypersomnia
This review details most of those disorders, including narcolepsy with and without cataplexy, idiopathic hypersomnia with and without long sleep time, recurrent hypersomnia, behaviorally induced insufficient sleep syndrome, hypersomnia due to medical [ncbi.nlm.nih.gov]
Convert to ICD-10-CM : 780.54 converts approximately to: 2015/16 ICD-10-CM G47.10 Hypersomnia, unspecified Approximate Synonyms Daytime hypersomnia Hypersomnia Hypersomnia (excessive sleeping) Hypersomnia, daytime Hypersomnia, idiopathic Idiopathic hypersomnia [icd9data.com]
ISCD-3 Central Disorders of Hypersomnolence (Open Table in a new window) Primary Secondary Narcolepsy type 1 (NT1) Narcolepsy type 2 (NT2) Hypersomnia due to a medical condition Hypersomnia due to a psychiatric condition Idiopathic hypersomnia (IH) Hypersomnia [emedicine.com]
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Fatigue
The only symptom is excessive fatigue. Secondary hypersomnia is due to other medical conditions. These can include sleep apnea, Parkinson’s disease, kidney failure, and chronic fatigue syndrome. [healthline.com]
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Dysostosis
Abstract Polysomnography and blood gas measurements during sleep in a young man with craniofacial dysostosis, who presented with an extremely severe sleep apnea syndrome, are reported. [ncbi.nlm.nih.gov]
Eyes
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Kayser-Fleischer Ring
Kayser-Fleischer ring was not detectable. D-penicillamine (DPA) was introduced. At 8-10 months after the initiation of the therapy the patient's complaints gradually resolved. [ncbi.nlm.nih.gov]
Workup
EEG
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Intermittent Slow Activity
Electroencephalographic (EEG) background activity for this individual was slightly slowed in the EEG during an episode of hypersomnia, and intermittent slow activity was found in addition. [ncbi.nlm.nih.gov]
Other Pathologies
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Gliosis
Severe neuronal loss and gliosis were observed in the midbrain and pontine raphe, particularly in dorsal raphe nucleus and superior central nucleus. Pontine and medullary reticular formation also showed a marked cell loss and fibrillary gliosis. [ncbi.nlm.nih.gov]
HLA Type
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HLA-DR1
Both patients share the same HLA haplotype (HLA-DR1, DQ1) which has been found in Kleine-Levin syndrome. [ncbi.nlm.nih.gov]
Treatment
Type and frequency of substance use were assessed at treatment entry. Substance use was also assessed 12 months following treatment completion. [ncbi.nlm.nih.gov]
Prognosis
The attacks usually continue indefinitely. x Prognosis The prognosis for persons with hypersomnia depends on the cause of the disorder. [ninds.nih.gov]
Referral to a sleep specialist is required in performing objective sleep studies, establishing the diagnosis, recommending treatment, and providing a prognosis. Many sleep disorders are treatable and aeromedically waiverable. [ncbi.nlm.nih.gov]
Prognosis The prognosis for persons with hypersomnia depends on the cause of the disorder. While the disorder itself is not life threatening, it can have serious consequences, such as automobile accidents caused by falling asleep while driving. [brainfacts.org]
Prognosis Hypersomnia can be chronic, especially when not associated with another disorder and therefore can continue to worsen if left untreated. Treatments are readily available and can improve the prognosis significantly. [allpsych.com]
What is the Prognosis of Idiopathic Hypersomnia? (Outcomes/Resolutions) The prognosis of Idiopathic Hypersomnia depends upon the severity of the symptoms. [dovemed.com]
Etiology
[…] the etiology or severity of centrally mediated hypersomnia. [ncbi.nlm.nih.gov]
Epidemiology
Epidemiology of narcolepsy : development of the Ullanlinna Narcolepsy Scale / Christer Hublin -- 14. Epidemiology of narcolepsy / Maurice M. Ohayon -- 15. [worldcat.org]
Articles were included if they were in English and included information regarding the epidemiology, diagnosis, pathophysiology, or treatment of IH or HD. [ncbi.nlm.nih.gov]
Summary Epidemiology The prevalence is unknown but has been estimated at 1/10,000 - 1/25,000 for the first form and 1/11,000 to 1/100,000 for the second one. Both forms start before the age of 25 years old and affect both sexes equally. [orpha.net]
Pathophysiology
Articles were included if they were in English and included information regarding the epidemiology, diagnosis, pathophysiology, or treatment of IH or HD. [ncbi.nlm.nih.gov]
Canine narcolepsy : history and pathophysiology / Emmanuel Mignot -- 24. Vigilance tests in narcolepsy / Johannes Mathis and Christian W. Hess -- 25. Lessons from sleepy mice : narcolepsy-cataplexy and the orexin neuropeptide system / Jon T. [worldcat.org]
Prevention
Thus, this case suggests that vitamin B12 may be effective for preventing recurrent hypersomnia. [ncbi.nlm.nih.gov]
If all these treatments are not helpful then the last resort is surgery to prevent blockage of airways while sleeping. [epainassist.com]
Physicians should give an attention to the sleep symptoms to prevent the delay in the diagnosis and effective intervention. [e-jsm.org]
Primary hypersomnias such as idiopathic hypersomnia and narcolepsy may not be preventable. [sleepopolis.com]