Presentation
Abstract Hypertrichosis lanuginosa congenita is a rare, autosomal dominant cutaneous disorder with sporadic presentations reported. [ncbi.nlm.nih.gov]
Abstract Abstract: Hypertrichosis lanuginosa congenita is a rare, autosomal dominant cutaneous disorder with sporadic presentations reported. [doi.org]
Entire Body System
- Fever
Selleks saadab esimees vastuvõetava teksti tehnilise komisjoni liikmetele en In children, the side effects seen in more than # % of patients were urinary tract infections, hypertrichosis (excess body hair), rhinitis (stuffy and runny nose), pyrexia (fever [et.glosbe.com]
English Common side effects (seen in more than 1, but less than 10 in 100 people taking Vectibix) were: • infusion type reactions (which may include signs and symptoms such as chills; and/ or pyrexia (fever or high temperature); • hypomagnesaemia (low [mymemory.translated.net]
Symptoms of causative disorders should be sought, including polyuria (diabetes), bingeing and purging (eating disorders), and weight loss and fevers (cancer). [merckmanuals.com]
- Asymptomatic
Here, we present images of distinct hypertrichosis in an otherwise asymptomatic one-year-old patient with pathogenic SURF1 gene mutations. [ncbi.nlm.nih.gov]
Otherwise, patients with CHL are typically asymptomatic. CHL has an unknown pathogenesis. It is thought to be inherited in an autosomal dominant manner; however, the specific genetic abnormality has not been discovered. [medicalbag.com]
Case Presentation We report the case of a Caucasian 80-year-old male referred to the Dermatology Department due to progressive asymptomatic hair growth on both forearms for three months. [hindawi.com]
- Sepsis
English The most commonly reported (> 20%) events following dual therapy in both (< 35 kg vs. 35 kg weight) cohorts were urinary tract infection, hypertrichosis, rhinitis, pyrexia, hypertension, upper respiratory tract infection, viral infection, sepsis [mymemory.translated.net]
# kg weight) cohorts were urinary tract infection, hypertrichosis, rhinitis, pyrexia, hypertension, upper respiratory tract infection, viral infection, sepsis and constipation en Common side effects (seen in more than #, but less than # in # people [et.glosbe.com]
- Turkish
Look up "hypertrichosis" at Merriam-Webster Look up "hypertrichosis" at dictionary.com In other languages: Spanish | French | Italian | Portuguese | Romanian | German | Dutch | Swedish | Russian | Polish | Czech | Greek | Turkish | Chinese | Japanese [wordreference.com]
A Turkish study involving 117 patients showed that post-cast hypertrichosis might occur in up to one third of patients.4 The study showed that there was no sex predisposition, but the frequency peaked in the adolescent age-group.4 Post-cast ALH has been [hkmj.org]
- Crying
This congenital disorder features marked hypertrichosis; cutis marmorata; hypoplastic genitalia, nipples, and umbilicus; growth and skeletal abnormalities; mental retardation; and a characteristic low-pitched and growling cry. [en.tzermias.gr]
Respiratoric
- Rhinitis
# kg weight) cohorts were urinary tract infection, hypertrichosis, rhinitis, pyrexia, hypertension, upper respiratory tract infection, viral infection, sepsis and constipation en Common side effects (seen in more than #, but less than # in # people [et.glosbe.com]
35 kg weight) cohorts were urinary tract infection, hypertrichosis, rhinitis, pyrexia, hypertension, upper respiratory tract infection, viral infection, sepsis and constipation. [mymemory.translated.net]
Gastrointestinal
- Constipation
# kg weight) cohorts were urinary tract infection, hypertrichosis, rhinitis, pyrexia, hypertension, upper respiratory tract infection, viral infection, sepsis and constipation en Common side effects (seen in more than #, but less than # in # people [et.glosbe.com]
35 kg weight) cohorts were urinary tract infection, hypertrichosis, rhinitis, pyrexia, hypertension, upper respiratory tract infection, viral infection, sepsis and constipation. [mymemory.translated.net]
- Diarrhea
Página 54 - Pedigree demonstrating a sex-linked recessive condition characterized by draining ears, eczematoid dermatitis and bloody diarrhea. Página 51 - Selective IgA deficiency: presentation of 30 cases and a review of the literature. [books.google.es]
Main side effects are gastrointestinal (anorexia, dyspepsia, nausea, vomiting, diarrhea, and abdominal pain) which are usually mild and transient, followed by neurological disorders (asthenia, headache, drowsiness, confusion, anxiety, and agitation) and [hindawi.com]
- Abdominal Distension
Hypertrophy of external genitalia, abdominal distension and slow growth may also be present. Donohue syndrome shows features similar to Berardinelli Seip syndrome but its course is more severe and insulin resistance is more precocious. [ijponline.biomedcentral.com]
Cardiovascular
- Hypertension
Sica, Minoxidil: An Underused Vasodilator for Resistant or Severe Hypertension, The Journal of Clinical Hypertension, 6, 5, (283-287), (2007). Domenic A. Sica and Todd W.B. [doi.org]
# kg weight) cohorts were urinary tract infection, hypertrichosis, rhinitis, pyrexia, hypertension, upper respiratory tract infection, viral infection, sepsis and constipation en Common side effects (seen in more than #, but less than # in # people [et.glosbe.com]
With Hypertrichosis, Hypertension, Overdevelopment of External Genitalia, Obesity, but Absence of Breast Enlargement - 24 Hours access EUR €36.00 GBP £28.00 USD $45.00 Rental This article is also available for rental through DeepDyve. [academic.oup.com]
35 kg weight) cohorts were urinary tract infection, hypertrichosis, rhinitis, pyrexia, hypertension, upper respiratory tract infection, viral infection, sepsis and constipation. [mymemory.translated.net]
Skin
- Hypertrichosis
From Wikimedia Commons, the free media repository Jump to navigation Jump to search hypertrichosis hair disease characterized by hair growth that is abnormal in quantity or location Upload media Wikipedia Instance of class of disease Subclass of hair [commons.wikimedia.org]
Hypertrichosis can develop all over the body or can be isolated to small patches. Hypertrichosis may be congenital (present at birth) or acquired (arises later in life). What causes hypertrichosis? The cause of hypertrichosis is unknown. [dermnetnz.org]
Hypertrichosis website. http://www.hypertrichosis.com/. Hypertrichosis lanuginosa congenital. Genetic and Rare Diseases Information Center (GARD). National Institutes of Health website. [medicalbag.com]
For example, terminology has included hypertrichosis universalis, hypertrichosis lanuginosa, congenital hypertrhicosis lanuginosa, and hypertrichosis universalis lanuginosa. [dermatology.cdlib.org]
- Hirsutism
hypertrichosis excessive hairiness; hirsutism. [medical-dictionary.thefreedictionary.com]
Synonyms Acquired hypertrichosis lanuginosa Androgen dependent hirsutism Androgen-dependent hirsutism Familial hirsutism Hirsutism (excess body hair) Hirsutism in female, androgen dependent Hirsutism, familial Hirsutism, idiopathic Hypertrichosis Hypertrichosis [icd9data.com]
Androgens and hirsutism Hirsutism may be a sign of a significant medical disorder. Hirsutism is caused by increased androgen action on hair follicles. [web.archive.org]
Hypertrichosis is excessive hair growth over and above the normal for the age, sex and race of an individual, in contrast to hirsutism, which is excess hair growth in women following a male distribution pattern. [dermnetnz.org]
Abrupt onset of hirsutism or hypertrichosis may indicate cancer. [merckmanuals.com]
- Dermatitis
Introduction Irritant contact dermatitis, allergic dermatitis, baboon syndrome, and cutaneous rash due to rivastigmine have been reported. [hindawi.com]
periorbitalni edem, kontaktni dermatitis, eritem, osip, sprememba barve dlak, nenavadna tekstura dlak, hipertrihoza, madaroza English dermatitis allergic, periorbital oedema, dermatitis contact, erythema, rash, hair colour changes, hair texture abnormal [mymemory.translated.net]
Duration of cast application, session of cast application, presence of lymphedema, contact dermatitis and pruritus between patients with hypertrichosis and without hypertrichosis were similar (p > 0.05). [ncbi.nlm.nih.gov]
—A Dermat develop Diagnosis.—The dilated disease disorder eczema employed epidermis eruption erythema Etiology Etiology and Pathology. [books.google.com]
- Skin Disease
[…] patients, and nutritional and metabolic diseases and the skin. [books.google.com]
Congenital hypertrichosis lanuginosa (CHL) is an extremely rare skin disease that has fascinated the public since the Middle Ages. [medicalbag.com]
Homepage Rare diseases Search Search for a rare disease X-linked congenital generalized hypertrichosis Disease definition X-linked congenital generalized hypertrichosis is an extremely rare type of hypertrichosis lanuginosa congenita, a congenital skin [orpha.net]
On DermNet NZ Excessive hair Hirsutism Hypertrichosis lanuginosa acquisita Other websites Congenital Hypertrichosis Lanuginosa – emedicine dermatology, the online textbook Books about skin diseases See the DermNet NZ bookstore . [dermnetnz.org]
- Erythema
Erythema multiforme/drug eruptions: Stevens-Johnson syndrome · Toxic epidermal necrolysis · Erythema nodosum Other erythema: Erythema annulare centrifugum · Erythema marginatum · Necrolytic migratory erythema · Erythema toxicum Radiation-related disorders [wikidoc.org]
—The dilated disease disorder eczema employed epidermis eruption erythema Etiology Etiology and Pathology. [books.google.com]
Frequency: 2 Quality: Slovenian alergijski dermatitis, periorbitalni edem, kontaktni dermatitis, eritem, osip, sprememba barve dlak, nenavadna tekstura dlak, hipertrihoza, madaroza English dermatitis allergic, periorbital oedema, dermatitis contact, erythema [mymemory.translated.net]
Psychiatrical
- Fear
It is important to remove the fear that shaving leads to increased growth of coarse hair growth or pigmentation.[17] The disadvantage of shaving, particularly for the facial hair is the need to shave daily. [e-ijd.org]
Urogenital
- Oligomenorrhea
Oligomenorrhea is defined as menstrual cycles of >35 days, with fewer than eight menstrual cycles defined as chronic anovulation. [en.tzermias.gr]
Hirsutism and oligomenorrhea suggest 21-hydroxylase deficiency (elevated 17-alpha-hydroxyprogesterone). [emedicine.medscape.com]
[…] anovulation; 6) deficient conversion of androgens into estrogens, with the consequent androgenic accumulation in the follicles; 7) excessive ovarian production of androgens; 8) the resulting increased blood levels of androgens; 9) menstrual disorders like oligomenorrhea [mum.org]
Neurologic
- Irritability
Theoretically a safe treatment but may cause skin reaction/irritation. Depilate with creams which dissolve hair at the skin level. Stubble is avoided, but skin irritation may result. Creams based on thiols may have a pungent odour. [hairscientists.org]
Introduction Irritant contact dermatitis, allergic dermatitis, baboon syndrome, and cutaneous rash due to rivastigmine have been reported. [hindawi.com]
Depilatories should not be used more often than every other day owing to the potential for irritation, and the area should be thoroughly rinsed and topical emollients or 1% hydrocortisone cream applied to minimize irritation further. [hairtx.com]
Sulfide preparations are more effective, but are more irritating to the skin and have a strong unpleasant odor.[18] Thioglycolates too have a high irritancy potential and may cause allergic contact dermatitis. [e-ijd.org]
Acquired Localized Hypertrichosis Anything that causes irritation or trauma can develop hypertrichosis on the area of the body which is being overused, abused, or exhausted. Examples were enumerated in the Causes section of this article. [emedicalhub.com]
- Confusion
Hypertrichosis may be confused with hirsutism. Hirsutism is a more common condition that causes women to grow coarse hair in areas that men typically do, such as on their chin. [medicalnewstoday.com]
However, the X-linked syndrome of hypertrichosis associated with gingival hyperplasia is often confused with congenital hypertrichosis lanuginosa. [emedicine.medscape.com]
Hypertrichosis is not to be confused with Hirsutism. Hirsutism occurs in women only. The condition presents similarly to Hypertrichosis, but is related to a congenital defect of the hormones in most cases. [babymed.com]
But sometimes this leads to confusion in diagnosis. Excess growth of body hair is normal in the following group of women. [web.archive.org]
- Poor or Absent Speech
[…] or absent speech, wide-based or absent gait, coarse facies, and cerebellar atrophy (summary by Thomas et al., 2014). [ncbi.nlm.nih.gov]
Workup
Workup of Hirsutism History Age of onset : Hirsutism, which is noticed from puberty, is indicative of idiopathic hirsutism. Hirsutism starting at middle/older age is indicative of adrenal or ovarian tumors. [lecturio.com]
Therefore, a clinical diagnostic workup to rule out these pathologies is necessary. [dovepress.com]
Treatment
Drug-induced hypertrichosis What is the treatment for hypertrichosis? Treatment of hypertrichosis is basically hair removal. Several methods are available but need to be repeated regularly as hair continues to grow back. [dermnetnz.org]
After 10 years, the areas of paradoxical hair growth were sparser compared to immediate post-treatment but remained denser compared to pre-treatment. This case illustrates improvement in the condition over time without intervention. [ncbi.nlm.nih.gov]
Summary Generalized hypertrichosis is a common side‐effect of oral minoxidil treatment for hypertension. [doi.org]
Prognosis
[…] lichen planus lotion lupus lymph-nodes majority of instances malady mercury nails nodules occasionally occur ointment oval papilla papillary papular papules particularly patches patient pediculosis pemphigus percent Phila pigmentation present probably Prognosis [books.google.com]
Because acquired hypertrichosis lanuginosa typically occurs late in the course of the malignancy, the overall prognosis is poor. However, regression of hair growth is known to occur if the tumour is treated or removed. [dermnetnz.org]
Management and prognosis The current literature focuses predominantly on diagnosis of AS cases rather than management. The first described patient, Petrus Gonzales, lived a long life and was able to procreate [ 1 ]. [dermatology.cdlib.org]
Management and prognosis The current literature focuses predominantly on diagnosis of AS cases rather than management. The first described patient, Petrus Gonzales, lived a long life and was able to procreate [1]. [escholarship.org]
Suitable technologies include 755nm Alexandrite laser, 1064nm Nd:Yag laser, diode laser, intense pulsed light (IPL) and electrolysis. [49] Prognosis The prognosis of hypertrichosis varies, depending on the type of hypertrichosis. [ncbi.nlm.nih.gov]
Etiology
—The dilated disease disorder eczema employed epidermis eruption erythema Etiology Etiology and Pathology. [books.google.com]
Despite an attempt to find etiologic factors in our patients and in the literature, none could be elicited. [ncbi.nlm.nih.gov]
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
Epidemiology
Summary Epidemiology BBS is a rare entity described in eleven patients to date. [orpha.net]
The longer wavelength Nd: YAG laser is considered safest in treating darker skin phototypes. [6] Reporting such rare syndromes not only adds to the database, but pooled data analysis may give us a better insight into patterns of inheritance, epidemiology [ijdvl.com]
Descriptive epidemiology of Cornelia de Lange syndrome in Europe. Am J Med Genet A. 2008;146A:51-59. 5. Schaffer JV, Chang MW, Kovich OI, et al. Pigmented plexiform neurofibroma: distinction from a large congenital melanocytic nevus. [consultant360.com]
Epidemiology of Hirsutism Hirsutism affects around 10 % of women in the US. Hirsutism is one of the most common health problems of women in reproductive age. The prevalence ranges from 4.3 to 10.8 % in blacks and whites respectively. [lecturio.com]
[…] localized hypertrichosis can also be iatrogenic; it has been described following PUVA therapy, topical corticosteroids, tacrolimus, creams containing mercury or iodine, anthralin, and prostaglandin F-2 alpha analogues (latanoprost, bimatoprost).[31] Epidemiology [ncbi.nlm.nih.gov]
Pathophysiology
Stimulation of the growth of hair via adrenal androgens by thyroid stimulating hormone may be the pathophysiological mechanism in our patient. [nature.com]
Aetiology and pathophysiology of hair loss. Dermatologica. 1987;175 Suppl 2:23-8. PubMed 11. Macias-Flores MA, Garcia-Cruz D, Rivera H, Escobar-Lujan M, Melendrez-Vega A, Rivas-Campos D, Rodriguez-Collazo F, Moreno-Arellano I, Cantu JM. [dermatology.cdlib.org]
Hypertrichosis of the auricle and hypertrichosis of the nasal tip, types of hereditary hypertrichosis, primarily affect males.[32][33] Pathophysiology The pathophysiology of hypertrichosis varies depending on the etiology. [ncbi.nlm.nih.gov]
Prevention
Hormonal therapy and antiandrogen therapy can help to reestablish the balance of estrogen to androgen, this reduces current hair and preventing further growth. [youtube.com]
However, this often results in hypertrichosis that can be severe enough to prevent its use. Diazoxide blocks insulin release from the pancreas by opening the SUR1/Kir6.2 channels in ß-cells. [ncbi.nlm.nih.gov]
Women should be warned not to expect improvement or at least 3–6 months after therapy is begun and lifelong therapy may be needed to prevent recurrence. [doi.org]