Hereditary disorders of purine metabolism with complete deficiency of hypoxanthine phosphoribosyl transferase (HPRT) result in the Lesch Nyhan syndrome, which consists of hyperuricemia, mental retardation, choreoathetosis, and self mutilation. [2] The [sjkdt.org]

To our knowledge, the vaginal itching and penile pain were not previously described. Family history was positive for stones and/or gout in 62.5%. [sjkdt.org]

Mean urinary uric acid decreased by over 300 mg/24 h at 3 months after entry and finally decreased to over 400 mg/24 h from baseline at 24 months post entry. [ncbi.nlm.nih.gov]