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Hypervitaminosis E


Presentation

  • None have presented with primarily neurologic or psychiatric involvement.[journals.lww.com]
  • Presenting signs Not reported in rabbits. Signs in humans include diarrhea, flatulence and bloating; this progresses to lethargy and weakness. Acute presentation No rabbit specific information recorded.[vetstream.com]
  • Hypervitaminosis E Vitamin E is present in a great many foods, particularly vegetable oils, unprocessed cereal grains, nuts and seeds. There is no evidence of any adverse effects from consuming vitamin E in food.[patient.info]
  • Because vitamin E can act as an anticoagulant and may increase the risk of bleeding problems, many agencies have set an upper tolerable intake level (UL) for vitamin E at 1,000 mg (1,500 IU) per day. [1] Symptoms and presentation See also Vitamin poisoning[wikidoc.org]
  • Foods 40 Favism x 47 Cyanogenetic Glycosides 58 58 Antivitamins in Foods 98 Natural Cholinesterase Inhibitors in Foods 112 Toxicity of the Vitamins 183 Excesses of Indispensable Amino Acids 221 Toxicity of the Essential Minerals 229 Toxic Substances Present[books.google.de]
Sepsis
  • Johnson L, Bowen FW Jr, Abbasi S, Herrmann N, Weston M, Sacks L, Porat R, Stahl G, Peckham G, Delivoria-Papadopoulos M, Quinn G, Schaffer D (1985) Relationship of prolonged pharmacologic serum levels of vitamin E incidence of sepsis and necrotizing enterocolitis[link.springer.com]
  • […] intracranial hemorrhage , hemolytic anemia and retrolental fibroplasia . [68] A 2003 Cochrane review concluded that vitamin E supplementation in preterm infants reduced the risk of intercranial hemorrhage and retinopathy, but noted an increased risk of sepsis[en.wikipedia.org]
  • […] intracraniaw hemorrhage , hemowytic anemia and retrowentaw fibropwasia . [63] A 2003 Cochrane review concwuded dat vitamin E suppwementation in preterm infants reduced de risk of intercraniaw hemorrhage and retinopady, but noted an increased risk of sepsis[wikien4.appspot.com]
Intracranial Hemorrhage
  • From 1949 onward there were trials with premature infants suggesting that oral alpha-tocopherol was protective against edema , intracranial hemorrhage , hemolytic anemia and retrolental fibroplasia . [68] A 2003 Cochrane review concluded that vitamin[en.wikipedia.org]

Workup

  • (See Prognosis, Workup , Treatment , and Medication .) Vitamin A An important fat-soluble vitamin, vitamin A’s basic molecule is a retinol, or vitamin A alcohol.[emedicine.medscape.com]

Treatment

  • Some amount of liver, kidney, nervous system damage may be observed, if the treatment is delayed.[dovemed.com]
  • Treatment : none as rare. Prognosis : depends on severity. Presenting signs Not reported in rabbits. Signs in humans include diarrhea, flatulence and bloating; this progresses to lethargy and weakness.[vetstream.com]
  • […] color to the skin Vision changes Vomiting These tests may be done if a high vitamin A level is suspected: Bone x-rays Blood calcium test Cholesterol test Liver function test Blood test to check vitamin A level Blood test to check other vitamin levels Treatment[medlineplus.gov]
  • It may also be caused by long-term use of certain acne treatments that contain high doses of vitamin A, such as isotretinoin (Sotret, Absorica). Acute vitamin A toxicity is usually the result of accidental ingestion when it occurs in children.[healthline.com]
  • Subject to testing, the hypothesis suggests that parasite vitamin A metabolism could become a new target for the treatment and prevention of malaria.[flipper.diff.org]

Prognosis

  • Prognosis Mortality is rare. Once identified, the prognosis is good. The yellow coloration of skin will reverse with time.[patient.info]
  • The prognosis is excellent, if the condition is recognized early and treated appropriately Individuals with severe conditions of Hypervitaminosis A may require hospitalization with extended treatment.[dovemed.com]
  • Prognosis : depends on severity. Presenting signs Not reported in rabbits. Signs in humans include diarrhea, flatulence and bloating; this progresses to lethargy and weakness. Acute presentation No rabbit specific information recorded.[vetstream.com]
  • Prognosis The prognosis for reversing vitamin toxicity is excellent for most patients. Side effects usually go away as soon as overdoses are stopped.[encyclopedia.com]
  • (See Prognosis, Workup , Treatment , and Medication .) Vitamin A An important fat-soluble vitamin, vitamin A’s basic molecule is a retinol, or vitamin A alcohol.[emedicine.medscape.com]

Etiology

  • (Etiology) The body requires a specific amount of vitamin A each day. The liver stores vitamin A, which gets transported to various parts of the body by a specific protein, termed as retinol-binding protein.[dovemed.com]
  • […] the United States population aged 1 year and older took a multivitamin supplement in a given month. [3] In a 2009 survey, 56% of US consumers said they take vitamins or supplements, with 44% saying they take them daily. [ 4 ] (See Pathophysiology and Etiology[emedicine.medscape.com]
  • Vitamin B 6 has been shown in at least two small-scale clinical studies to have a beneficial effect on the syndrome, particularly in cases where no trauma or overuse etiology is known.[allaboutheaven.org]

Pathophysiology

  • […] in 2003–2006 33% of the United States population aged 1 year and older took a multivitamin supplement in a given month. [3] In a 2009 survey, 56% of US consumers said they take vitamins or supplements, with 44% saying they take them daily. [ 4 ] (See Pathophysiology[emedicine.medscape.com]

Prevention

  • "Vitamin E supplementation for prevention of morbidity and mortality in preterm infants" . Cochrane Database Syst Rev (4): CD003665. doi : 10.1002/14651858.CD003665 . PMID 14583988 . External links [ edit ][en.wikipedia.org]
  • Prevention Toxicity from excess of vitamins A and D and, exceptionally, vitamin E, can occur but it is important not to exaggerate the risk .[patient.info]
  • Prevention Hypervitaminosis A can be prevented by not ingesting more than the Tolerable Upper Level of intake for Vitamin A. This level is for synthetic and natural retinol ester forms of vitamin A. Carotene forms from dietarysources are nottoxic.[flipper.diff.org]
  • As of March 2018, EFSA has not evawuated any vitamin E and cancer prevention cwaims.[wikien4.appspot.com]

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