The present report is of an adult male with this syndrome and demonstrates several interesting features. CASE REPORT Present Illness: A 25 year old Mexican drug store clerk was first seen by us on March 3, FULL TEXT [annals.org]

A careful drug history to uncover possible isotretinoin use is important in patients presenting with manifestations suggestive of vitamin A intoxication. [emedicine.medscape.com]

Usually, since the water soluble vitamins (B6, B12, Biotin, Folic Acid, Thiamin, Riboflavin, Niacin, Vitamin C, Pantothenic Acid) are not stored in our body and the extra amounts are excreted as waste, they do not present a high level of risk for our [enotes.com]

All material presented here is unclassified. C. 2009, 2014, All Rights Reserved [brooksidepress.org]

Hypervitaminosis E Vitamin E is present in a great many foods, particularly vegetable oils, unprocessed cereal grains, nuts and seeds. There is no evidence of any adverse effects from consuming vitamin E in food. [patient.info]

• Hepatosplenomegaly

  Chronic intoxication → Anorexia, dry Itchy skin, wt. loss, painful extremities, sparse hair, Hepatosplenomegaly, hypoplastic anemia and Benign I.C. Hypertension. c. Normally, vit. [gradestack.com]

  Other symptoms can be quite nonspecific: Scaly seborrhoeic eczema Patchy hair loss Stomatitis Loss of appetite Nausea Vomiting Malaise Hepatosplenomegaly Liver failure Raised intracranial pressure Children can present with craniotabes, irritability, failure [patient.info]

  […] retina) Integrity of epithelia Lysosome stability Glycoprotein synthesis Deficiency: Night blindness, perifollicular hyperkeratosis, xerophthalmia, keratomalacia, increased morbidity and mortality in young children Toxicity: Headache, peeling of skin, hepatosplenomegaly [msdmanuals.com]

  […] and promote the development of osteoporosis. [5, 44] Manifestations of chronic vitamin A toxicity also include the following: Alopecia Erythematous dermatitis Skin desquamation Brittle nails Exanthema Cheilitis Conjunctivitis Petechiae Liver cirrhosis Hepatosplenomegaly [emedicine.medscape.com]

• Sparse Hair

  Chronic intoxication → Anorexia, dry Itchy skin, wt. loss, painful extremities, sparse hair, Hepatosplenomegaly, hypoplastic anemia and Benign I.C. Hypertension. c. Normally, vit. [gradestack.com]

• Sparse Hair

  Chronic intoxication → Anorexia, dry Itchy skin, wt. loss, painful extremities, sparse hair, Hepatosplenomegaly, hypoplastic anemia and Benign I.C. Hypertension. c. Normally, vit. [gradestack.com]

Search: name, specialism, conditions, treatments, tests or services Search: name, specialism, conditions, treatments, tests or services Search: name, specialism, conditions, treatments, tests or services Royal Brompton & Harefield NHS Foundation Trust [rbht.nhs.uk]

Treatment In all cases, treatment of vitamin toxicity requires discontinuing vitamin supplements. [encyclopedia.com]

Oral doses of 2mg are adequate. treatment: 1mg SQ or IM, in conjunction with proper laboratory testing of PT. Hypoprothrombinemia in adults: 2.5-25mg. Amount and route of administration depends on severity of disease. [oacapps.med.jhmi.edu]

Total body Mg stores may not be reflected by serum Mg levels and may need prolonged treatment for complete replacement. As serum Mg rises with treatment, significant ongoing renal loss may require additional treatment. [clinicaladvisor.com]

Prognosis Mortality is rare. Once identified, the prognosis is good. The yellow coloration of skin will reverse with time. [patient.info]

Prognosis The prognosis for reversing vitamin toxicity is excellent for most patients. Side effects usually go away as soon as overdoses are stopped. [encyclopedia.com]

Vitamin A status as a marker of prognosis in cystic fibrosis. Abstract book, 11th International CF Congress, Dublin 1992. Poster MP73. Rayner RJ, Tyrell JC, Hiller EJ, et al. [cfmedicine.com]

Isotretinoin (Accutane), a drug used for the treatment of severe forms of acne, is closely related to the chemical structure of vitamin A and therefore has similar pharmacologic and toxic attributes (see Pathophysiology and Etiology). [emedicine.medscape.com]

6 hypervitaminoses are associated with side effects that usually rapidly subside with supplement reduction or cessation. [ citation needed ] Prevention [ edit ] Do not take more than the normal or recommended amount of multivitamin supplements. [3] Epidemiology [en.wikipedia.org]

Hygiene and epidemiology : selected chapters. 2. edition. Prague. 2008. ISBN 80-246-0793-X. [wikilectures.eu]

Acknowledgements Robert A Adler, MD Chief of Endocrinology and Metabolism, McGuire Veterans Affairs Medical Center; Professor, Departments of Internal Medicine and Epidemiology and Community Health, Virginia Commonwealth University Robert A Adler, MD [emedicine.medscape.com]

Isotretinoin (Accutane), a drug used for the treatment of severe forms of acne, is closely related to the chemical structure of vitamin A and therefore has similar pharmacologic and toxic attributes (see Pathophysiology and Etiology). [emedicine.medscape.com]

It is associated with significant mortality risk and its pathophysiology is usually multifactorial, chiefly reduced renal function and drugs. [clinicaladvisor.com]

[…] has been described in at least 17 infants and young children since Josephs' original article in 1944. 1, 2 Sulzberger and Lazar 3 described similar toxic symptoms which occurred in an adult female who took large amounts of vitamin A in an attempt to prevent [annals.org]

Eijkman, essence in outer coating of rice prevents illness Correlation between chemicals factors and cures for deficiencies Many discovered during the late 19th, early 20th century As they were discovered were labeled using letters (A, B, C, D, E) until [www2.highlands.edu]

Warfarin inhibits vitamin K by preventing its enzymatic reactivation. Pathological manifestations are rare. Hypovitaminosis K can lead to jaundice and anemia in the neonate. [radiopaedia.org]

Prevention Vitamin toxicity can be prevented by minimizing the use of vitamin supplements or by only taking a dose within recommended levels of the DRI or RDA. [encyclopedia.com]

In some therapeutic dose of vitamin B complex vitamins exceed the daily allowance for healthy people, these drugs can not be used as a preventive measure. [mymedinform.com]