The abdomen is enlarged, and excess fluid may build up in the body before birth (a condition called hydrops fetalis). [en.wikipedia.org]

The abdomen is enlarged, and excess fluid may build up in the body before birth (a condition called hydrops fetalis). Prognosis - Hypochondrogenesis Not supplied. Treatment - Hypochondrogenesis There is no cure or treatment for hypochondrogenesis. [checkorphan.org]

Individuals with hypochondrogenesis have an enlarged abdomen and may have a condition called hydrops fetalis in which excess fluid builds up in the body before birth. [ghr.nlm.nih.gov]

Characterized by severe micromelia, lack of vertebral ossification, and a large head with relatively normal ossification of the calvarium; also associated with polyhydramnios, cystic hygroma, and hydrops fetalis. [mhmedical.com]

fetalis Treatment and prognosis The prognosis is generally poor, with most infants being stillborn or dying soon after birth. [radiopaedia.org]

Affected infants have short arms and legs, a small chest with short ribs, and underdeveloped lungs. The spinal bones (vertebrae) in the neck and part of the pelvis (the sacrum) do not harden, or ossify, properly. [en.wikipedia.org]

Affected infants have short arms and legs, a small chest with ... 1 ... [familydiagnosis.com]

Diagnosis - Hypochondrogenesis Affected infants have short arms and legs, a small chest with short ribs, and underdeveloped lungs. The spinal bones (vertebrae) in the neck and part of the pelvis (the sacrum) do not harden, or ossify, properly. [checkorphan.org]

Affected infants have short arms and legs, a small chest with short ribs, and underdeveloped lungs. Bones in the skull appear normal, but the bones of the spine (vertebrae) and pelvic bones do not harden properly. [medic8.com]

Affected infants have short arms and legs, a small chest with short ribs, and underdeveloped lungs. Bones in the skull develop normally, but the bones of the spine (vertebrae) and pelvis do not harden (ossify) properly. [ghr.nlm.nih.gov]

Infants with hypochondrogenesis have short legs and arms and underdeveloped lungs encased in a small chest with short ribs. Their bones particularly in the spine, neck and pelvis are soft. [illnessopedia.org]

Infants with hypochondrogenesis have short legs & arms & underdeveloped lungs encased in a small chest with short ribs. Their bones particularly in the spine, neck & pelvis are soft. [signssymptoms.org]

Genetic profile Hypochondrogenesis is caused by a mutation, or change, in the COL2A1 gene located on the long arm of chromosome 12 (12q13.11-q13.2). [encyclopedia.com]

On physical examination the baby had macrocephaly, large anterior fontanelle, flat occiput, hypertelorism, depressed nasal bridge, anteverted nostrils, long philtrum, deformed low set ears, atretic ear canal, short neck, short thorax, hypertrichosis, [pediatriconcall.com]

Biochemical studies (see companion paper) suggest that this patient had a new dominant lethal disorder caused by a structural abnormality of type II collagen. [ncbi.nlm.nih.gov]