Atypical Presentation of Acquired Hypoganglionosis in a Patient Taking Clozapine. Gisi C, Munteanu A, Ku L, French S, Fleischman M, Eysselein V. Gisi C, et al. [pubmed.ncbi.nlm.nih.gov]

Thirty-eight patients presented in the neonatal period. A total of 13 (22.4%) presented with enterocolitis, 43 (74.1%) with intestinal obstruction, and 2 (3.5%) with severe constipation. [scienceopen.com]

• Pathologist

  Practical guidelines are provided to assist surgical pathologists, who are likely to encounter this condition only infrequently. [pubmed.ncbi.nlm.nih.gov]

• Constipation

  The Constipation Guideline Committee of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) has formulated a clinical practice guideline for the management of pediatric constipation. [scienceopen.com]

  Virchows Arch 426: 549–556 Article PubMed Google Scholar Meier-Ruge WA, Bruder E (2005) Pathology of chronic constipation in pediatric and adult coloproctology. [link.springer.com]

  The incidence of hypoganglionosis in chronic slow-transit constipation in the distal colon of adults was about 33% in 759 cases. [de.glosbe.com]

  Hypoganglionosis comprises 3–5% of gastrointestinal innervation defects which are connected to therapy-resistant chronic constipation in children and adults. [infona.pl]

  A history of chronic constipation was reported since childhood, but this condition had never been investigated. A preoperative CT scan showed a megasigmoid and megarectum. A Hartmann's procedure was performed. [pubmed.ncbi.nlm.nih.gov]

The guideline provides recommendations for management by the primary care provider, including evaluation, initial treatment, follow-up management, and indications for consultation by a specialist. [scienceopen.com]

A mechanograph was used to evaluate in vitro colonic responses to electrical field stimulation (EFS) of the adrenergic and cholinergic nerve before and after treatment with various autonomic nerve blockers and gastrointestinal hormones. [thieme-connect.com]

Chronic intestinal pseudo-obstruction: treatment and long term follow-up of 44 patients. Arch Dis Child 1999; 81: 21 – 7. 10. Ciftci AO, Cook RC, van Velzen D. [tidsskriftet.no]

Diagnosis and treatment of chronic intestinal pseudo-obstruction in children: report of a consensus workshop. J Pediatr Gastroenterol Nutr. 1997;24:102–112. Thapar N, Saliakellis E, Benninga MA, et al. [pubmed.ncbi.nlm.nih.gov]

Gastrointest Radiol 12: 262–264 Article PubMed Google Scholar Meier-Ruge W (1992) Epidemiology of congenital innervation defects of the distal colon. [link.springer.com]

Pathophysiology of hypoganglionosis. J Pediatr Gastroenterol Nutr. 2002;34:231–35. - PubMed Publication types MeSH terms LinkOut - more resources Full Text Sources Europe PubMed Central International Scientific Literature, Ltd. [pubmed.ncbi.nlm.nih.gov]

This article discusses the commonest pediatric anorectal disorders, emphasizing the differences between children and adults in terms of clinical presentations, pathophysiology, diagnosis, and treatment. [scienceopen.com]