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Hypophysectomy

Hypophysectomies


Presentation

  • In the present paper, the authors present the case of a 53-year-old patient with a history of transsphenoidal hypophysectomy and adjuvant radiotherapy, who underwent strabismus surgery for abducens palsy.[ncbi.nlm.nih.gov]
  • Abstract The effect of transsphenoidal hypophysectomy is presented in 60 patients with visual impairment due to a pituitary adenoma, derived from a total series of 194 patients.[ncbi.nlm.nih.gov]
  • A 42-year-old, 75-kg, ASA physical status III, white male presented 8 months after suffering a head injury in which he was knocked unconscious for approximately 3 minutes.[ncbi.nlm.nih.gov]
  • The most common symptoms included headaches and nasal discharge present for an average of 2.9 years. Medical management resulted in resolution of symptoms in 5 of 10 cases (50%).[ncbi.nlm.nih.gov]
  • The authors present the case of a 63-year-old man with metastatic prostate cancer who presented with high serum prostate-specific antigen levels (1216 microg/L) and cavernous sinus syndrome.[ncbi.nlm.nih.gov]
Asymptomatic
  • Most of the complications were asymptomatic. Thirteen percent of the patients had septal perforations, 3.5% epistaxis, and 36% complained of mild dryness of the nose. An improvement in breathing was noted in 24% of the patients.[ncbi.nlm.nih.gov]
  • Complications included 8 symptomatic anterior septal perforations and 13 asymptomatic posterior perforations.[ncbi.nlm.nih.gov]
Sepsis
  • Abstract Experimental models of lethal endotoxemia in rodents are widely used to delineate pathogenic mechanisms of inflammation, sepsis, and septic shock.[ncbi.nlm.nih.gov]
Lip Numbness
  • In our series, we found that 18% of patients had a postoperative septal perforation, 2% of which were symptomatic; 6% of patients reported nasal cosmetic deformity; 13% reported transient lip numbness; and 3% reported postoperative nasal dysfunction.[ncbi.nlm.nih.gov]
Strabismus
  • In the present paper, the authors present the case of a 53-year-old patient with a history of transsphenoidal hypophysectomy and adjuvant radiotherapy, who underwent strabismus surgery for abducens palsy.[ncbi.nlm.nih.gov]

Treatment

  • […] of hormone treatment may be beneficial in similar cases.[ncbi.nlm.nih.gov]
  • Following a well-defined gonadotropin rise with initiation of LH-RH treatment, no further response was noted. Stabilization of the LH:FSH ratio in PCOD patients was noted after 4 weeks of treatment.[ncbi.nlm.nih.gov]
  • Abstract The influence of hypophysectomy on biochemical indices of striatal dopamine target cell supersensitivity induced by prolonged haloperidol treatment was investigated in the rat.[ncbi.nlm.nih.gov]
  • In four patients replacement hormone therapy is no longer required and a further four take only partial treatment. We conclude that transphenoidal hypophysectomy is an effective treatment for Cushing's disease.[ncbi.nlm.nih.gov]
  • Chronic treatment of hypophysectomized animals with human GH also caused significant changes in gene expression patterns.[ncbi.nlm.nih.gov]

Prognosis

  • Complications Usually, this surgery has an excellent prognosis. Little risk is involved with the process. However, the operation can lead to Postoperative Hypoadrenalism if carried out improperly.[primehealthchannel.com]

Etiology

  • Diet as an etiological factor in the development of cancers of the colon and rectum. ‎ Página 71 - MC Pike, BE Henderson, RI Pfeffer. VR Gerkins, M.[books.google.es]

Prevention

  • The most important morbidity is the intraoperative cerebrospinal fluid (CSF) leakage, which is inherent to this technique and can be successfully prevented with a pedicled nasoseptal flap reconstruction.[ncbi.nlm.nih.gov]
  • As obliteration with fat is intended to prevent cerebrospinal fluid (CSF) leakage, an alternative for this technique would be techniques used for CSF rhinorrhea repair.[ncbi.nlm.nih.gov]
  • Insulin, but not hGH, prevented an increase in CYP2E1 mRNA in diabetic rats.[ncbi.nlm.nih.gov]
  • Hypocortisolism-rationale: although steroids should be given during surgery to prevent hypocortisolism, the nurse should assess the client for it. abrupt withdrawal of endogenous cortisol may lead to severe adrenal insufficiency. signs of hypocortisolism[proprofs.com]
  • The most important one is to prevent cerebral oedema caused by retraction of the frontal lobe for a long time.[link.springer.com]

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