Abstract In the present study, the prevalence of thromboembolic events in patients suffering from type I plasminogen deficiency was evaluated. [ncbi.nlm.nih.gov]

PowerPoint presentation at Hadassah Medical Center Jerusalem: Jerusalem, Israel. [plasminogen.com]

Pseudomembraneous lesions are present on affected mucous membranes, such as eye, middle ear, pharynx, duodenum, oral cavity, upper and lower respiratory tracts, and female genital tract. [xpertdox.com]

We are presenting a case of 35 years old female suffering from ligneous conjunctivitis which was removed surgically. [tjmrjournal.org]

Regarding biochemistry, there was an increase of 25% in the dosage of the patient's functional plasminogen, that is, at the onset of treatment the patient presented 20% of serum plasminogen, and three years after the onset she presented 25% in the total [scielo.br]

PLG testing should not be included in routine thrombophilia workup. Mehta R, Shapiro AD. Plasminogen deficiency. Haemophilia. 2008 Nov. 14(6):1261-8. [Medline]. Schuster V, Hügle B, Tefs K. Plasminogen deficiency. [emedicine.medscape.com]

Treatment Centers Edit Please add treatment centers available. Include contacts. Link any mentions you make to the online source if available. [wikicure.wikia.com]

Some of the commonly used treatment methods include surgical removal of the lesions, IV corticosteroid treatment, topical treatment with heparin, corticosteroids and alpha-chymotrypsin, or cyclosporine, hyaluronidase & azathioprine. [xpertdox.com]

Are you waiting for a treatment? Share your thoughts, and your hopes, with the Patient Worthy community! Related [patientworthy.com]

The nutritional treatment after three years of treatment of phases 1 and 2 showed an increase of 25% in the dosage of plasminogen. [scielo.br]

Up-to-date concepts of pathogenesis and disease management help you understand the diseases that affect oral and maxillofacial structures, formulate an accurate diagnosis, and institute proper treatment. [books.google.de]

Prognosis In milder cases were only the conjunctivae are involved the visual prognosis is moderate, however, the prognosis for severe cases with multiorgan involvement is very poor. [orpha.net]

[…] includes a brief description of each individual lesion or pathologic condition and the kind of pathologic process that it represents, followed by a discussion of its clinical and/or radiographic presentation, histopathologic features, and its treatment and prognosis [books.google.de]

Diagnosis - Congenital Plasminogen Deficiency Prognosis - Congenital Plasminogen Deficiency Not supplied. Treatment - Congenital Plasminogen Deficiency Resources - Congenital Plasminogen Deficiency Not supplied. [checkorphan.org]

The prognosis is variable, depending on the extent, location, size, and site of the lesions. [xpertdox.com]

Prognosis The prognosis of ligneous conjunctivitis depends on the ability to control the inflammation and recurrence of the pseudomembranes. [eyewiki.aao.org]

Etiology Severe HPG is caused by homozygous or compound-heterozygous mutations in the plasminogen gene ( PLG ; 6q26). [orpha.net]

It has also been linked to congenital hydrocephalus and juvenile colloid milium. [1] Etiology Ligneous conjunctivitis may be inherited in an autosomal recessive pattern due to mutations in the plasminogen (PLG) gene and a variety of other genes, associated [eyewiki.aao.org]

[…] microduplication Silver-Russell syndrome due to imprinting defect of 11p15 Synonym(s): - Plasminogen deficiency type 1 Classification (Orphanet): - Rare genetic disease - Rare systemic or rheumatologic disease Classification (ICD10): (no data available) Epidemiological [csbg.cnb.csic.es]

Summary Epidemiology Prevalence of severe HPG is in the range of 1.6/1,000,000. [orpha.net]

Genatlas disease for PLG Gene thrombosis,recurrent,dysplasminogenemic type Relevant External Links for PLG Genetic Association Database (GAD) PLG Human Genome Epidemiology (HuGE) Navigator PLG Tumor Gene Database (TGDB): PLG Atlas of Genetics and Cytogenetics [genecards.org]

Linguistic Variant - Portuguese, Brazil) 2015AB LNC-RU-RU (LOINC Linguistic Variant - Russian, Russia) 2015AB LNC-TR-TR (LOINC Linguistic Variant - Turkish, Turkey) 2015AB LNC-ZH-CN (LOINC Linguistic Variant - Chinese, China) 2015AB MCM (Glossary of Clinical Epidemiologic [doctor.am]

Venous thromboembolism: epidemiology and magnitude of the problem. Best Pract Res Clin Haematol. 2012;25(3):235-42. 3. Anderson FA Jr, Wheeler HB, Goldbeig RJ, Hosmer DW, Patwardhan NA, Jovanovic B, et al. [degruyter.com]

Nathan and Oski’s is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. [books.google.de]

General Pathology The histology shows ulcerated conjunctiva with sub-epithelial, amyloid-like, eosinophilic material containing clotted fibrinogen and immunoglobulins, accompanied by lymphocytes, granulocytes, and plasma cells (Figure 1). [1] Pathophysiology [eyewiki.aao.org]

Pathophysiology of venous thrombosis, thrombophilia, and the diagnosis of deep vein thrombosis-pulmonarycmbolism in the elderly. Clin Geriatr Med. 2006;22:75-92. [degruyter.com]

Two of six patients with hypoplasminogenemia showed thrombotic events, and in one of these symptomatic cases the coexistence of factor V deficiency did not prevent the occurrence of thrombosis. [ncbi.nlm.nih.gov]

Collaborative Meta-Analysis of Randomised Trials of Antiplatelet Therapy for Prevention of Death, Myocardial Infarction, and Stroke in High Risk Patients. ‎ [books.google.ro]

[…] or diagnosis of a disease or condition for which no drug is currently marketed in Canada; or A significant increase in efficacy and/or significant decrease in risk such that the overall benefit/risk profile is improved over existing therapies, preventatives [biospace.com]

Priority review status is granted by Health Canada to a NDS for serious, life-threatening or severely debilitating diseases or conditions for which there is substantial evidence of clinical effectiveness that the drug provides: An effective treatment, prevention [markets.businessinsider.com]

Prevention - Congenital Plasminogen Deficiency Not supplied. Diagnosis - Congenital Plasminogen Deficiency Prognosis - Congenital Plasminogen Deficiency Not supplied. [checkorphan.org]