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Hypoplastic Kidney

Renal Hypoplasia


Presentation

  • The early detection of hemochromatosis in the presented case may delay organ damage and failure due to iron overload.[ncbi.nlm.nih.gov]
  • To report a case of 18-year-old girl presented with urinary leakage occurring between normal voids that at 11-year-old was found to have, at cistoscopy and vaginoscopy, an left ureteral ectopy into the vagina with a non demonstrable corresponding kidney[ncbi.nlm.nih.gov]
  • […] and Diagnosis 256 Double Urethra and Accessory Urethra 257 Incomplete Dorsal Accessory Urethrablind 258 Incomplete Dorsal Accessory UrethraCommunicating with the Urethra 259 Etiology and Pathology 261 Clinical Presentation 268 Diagnosis 270 Treatment[books.google.com]
  • Leading experts from Latin America, Africa, Near and Middle East, Indian Subcontinent, Far East, Oceania and Australia present their expert insights into specific conditions, as well as progress and challenges in the development of the specialty.[books.google.com]
  • Written by leading pathologists, this second edition presents an up-to-date , concise presentation of major pathological, clinical, pathophysiological, and genetic information for over 240 diagnoses .[books.google.com]

Workup

  • Topics include: Non-neoplastic diseases in kidney cancer; Nephrectomy for non-neoplastic causes; Autopsy renal pathology; Practical approach to kidney donation workup; Kidney allograft pathology; Renal infections; Amyloidosis - all subtypes; Histologic[books.google.com]
  • The thrombophilic workup was negative. Patients were treated with conservative therapy: low molecular weight heparin anticoagulants converted later to oral anticoagulant with resolution of symptoms and disappearance of the thrombus.[actamedicamarisiensis.ro]
Small Kidney
  • […] re·nal hy·po·pla·si·a an abnormally small kidney that is morphologically normal but has either a reduced number of nephrons or smaller nephrons. re·nal hy·po·pla·si·a ( rē'năl hī'pō-plā'zē-ă ) An abnormally small kidney that is morphologically normal[medical-dictionary.thefreedictionary.com]
  • Renal hypoplasia refers to a congenitally small kidney where there is essentially normal residual parenchyma but smaller calyces, lobules and papillae.[radiopaedia.org]
  • Definition of Renal Hypoplasia Renal hypoplasia is a congenital small kidney with diminished renal function, which has a normal tissue architecture. Epidemiology of Renal Hypoplasia 2.5% is the risk for unilateral renal hypoplasia.[urology-textbook.com]
  • In many cases, the small kidney also shows signs of dysplasia on ultrasound, leading to the diagnosis of renal hypodysplasia.[oxfordmedicine.com]

Treatment

  • Positive PET scan areas should be biopsied to confirm the presence of metastatic disease before excluding patients from surgical treatment.[ncbi.nlm.nih.gov]
  • When the corresponding kidney has a good function, the treatment of choice is the ureter reimplantation, otherwise the alternative is partial or total nephrectomy.[ncbi.nlm.nih.gov]
  • 271 Prognosis 278 References 281 Anomalies of the Male Genitalia By RoBERT J PRENTIss With 15 Figures 287 Method of Examination 288 Surgical Treatment 289 Surgical Principles 292[books.google.com]
  • Treatment In most cases, there is no treatment needed before birth. Options Very rarely, there is concern that the problems with the baby’s kidneys and/or lungs are very severe, and may mean that he or she will not be able to live a normal life.[infokid.org.uk]

Prognosis

  • Diagnosis 256 Double Urethra and Accessory Urethra 257 Incomplete Dorsal Accessory Urethrablind 258 Incomplete Dorsal Accessory UrethraCommunicating with the Urethra 259 Etiology and Pathology 261 Clinical Presentation 268 Diagnosis 270 Treatment 271 Prognosis[books.google.com]
  • Furthermore. the natural history and long-term renal prognosis of these diseases are poorly defined, thus making it difficult to predict renal outcomes of any individual patient with dysplastic or hypoplastic kidney [ 5 - 8 ].[wjnu.org]
  • Prognosis is directly related to the presence and severity of chronic kidney disease.[clinicaladvisor.com]
  • If the blood pressure can be satisfactorily controlled, the prognosis in unilateral renal hypoplasia seems to be rather good.[link.springer.com]
  • […] decompression or excision of cysts do not improve renal function There is no higher incidence of renal cell carcinoma in these patients 50% of the children of affected adults will have the disease When the disease affects children, it has a very poor prognosis[clevelandurology.net]

Etiology

  • […] and Pathology 254 Clinical Presentation and Diagnosis 256 Double Urethra and Accessory Urethra 257 Incomplete Dorsal Accessory Urethrablind 258 Incomplete Dorsal Accessory UrethraCommunicating with the Urethra 259 Etiology and Pathology 261 Clinical[books.google.com]
  • Hypothyroidism, usually of autoimmune etiology and only occasionally of nonautoimmune etiology, has been reported to be associated with dRTA.[thetrp.net]
  • Review paper about unilateral renal agenesis Ongoing controversies regarding etiology, diagnosis, treatment Long-term follow-up studies of patients with renal hypoplasia/dysplasia/agenesis are needed to provide insight into prognostic factors identified[clinicaladvisor.com]
  • The classification, etiology and significance of bilateral small kidneys in 11 children. Amer. J. Dis. Child. 109 , 130 (1965). PubMed Google Scholar 36.[link.springer.com]
  • ., Husmann, D.A. et al. (1994) Hydronephrosis in renal ectopia: Incidence, etiology and significance. J. Urol. 151, 1660–1661. PubMed Google Scholar Gray, S.W., Skandalakis, J.E. (eds) (1972) Embriology for Surgeons .[link.springer.com]

Epidemiology

  • Epidemiology of Renal Hypoplasia 2.5% is the risk for unilateral renal hypoplasia. Signs and Symptoms of Renal Hypoplasia Unilateral renal hypoplasia causes no symptoms. Bilateral renal hypoplasia can be the cause of renal insufficiency.[urology-textbook.com]
  • Epidemiology Frequency United States Exact frequency of oligomeganephronia is difficult to determine.[emedicine.medscape.com]
  • Epidemiology Incidence BRA is thought to occur in 1 in 5,000 births whilst unilateral renal agenesis (URA) is more common and occurs in about 1 in 1,000. [ 4 ] An Italian study showed a 5:2 male:female ratio. [ 5 ] Potter's original series similarly showed[patient.info]
Sex distribution
Age distribution

Pathophysiology

  • Written by leading pathologists, this second edition presents an up-to-date , concise presentation of major pathological, clinical, pathophysiological, and genetic information for over 240 diagnoses .[books.google.com]
  • Brenner/Rector remains the go-to resource for practicing and training nephrologists and internists who wish to master basic science, pathophysiology, and clinical best practices.[books.google.com]
  • View Article PubMed PubMed Central Google Scholar Hoyer JR, Seiler MW: Pathophysiology of Tamm-Horsfall protein. Kidney Int. 1979, 16: 279-289. 10.1038/ki.1979.130.[bmcnephrol.biomedcentral.com]
  • Pathophysiology Oligomeganephronia results from arrested development of the metanephric blastema at 14-20 weeks' gestation, with subsequent hypertrophy of glomeruli and tubules in the kidney.[emedicine.medscape.com]
  • CrossRef PubMed Google Scholar Koff, S.A. (1990) Pathophysiology of ureteropelvic junction obstructions. Urol. Clin. North. Am. 17, 263–272.[link.springer.com]

Prevention

  • […] urogenital anomalies, tongue cysts, limb shortness, eye abnormalities, defects of the heart, gallbladder agenesis, and ear malformations. 1953) observed that maternal vitamin A deficiency resulted in renal hypoplasia in rats which was reported to have been prevented[medical-dictionary.thefreedictionary.com]
  • Treatment is focused on preventing progression to stage 5, end-stage renal disease.[clinicaladvisor.com]
  • Some types of VUR may be treated with antibiotics to prevent infections, while others may require surgery to prevent the backflow of urine to occur.[nationwidechildrens.org]
  • Is chronic lung disease in low birth weight infants preventable? A survey of eight centers. ‎ Página 84 - Tanner JM, Whitehouse RH, Marubini E, Resele LF. The adolescent growth spurt of boys and girls of the Harpenden growth study. ‎[books.google.es]
  • OUTCOME Aggressive medical and surgical intervention should be able to prevent or treat most complications of these abnormalities.[chargesyndrome.org]

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