Hypospadias is a developmental anomaly characterized by an abnormally placed urinary meatus.
The diagnosis of hypospadias can be made using both prenatal fetal ultrasonography and MRI, but the diagnosis is generally made on examination of newborn infants . Some of the common presentations are as follows:
Physical examination is enough to demonstrate hypospadias . In cases where there is severe hypospadias like the absence of testicles in the scrotum, sex determination evaluation may be performed.
Upper urinary tract anomalies are rarely associated with hypospadias and thus there is no need for routine imaging in patients unless other organ system disorders are present. Some associated findings common with hypospadias include enlarged prostatic utricle and low-grade vesicouretreal reflux. However, none of these are of clinical importance except where the other symptoms fully merit evaluation.
The main goals in treating hypospadias are as follows :
The resulting penis should be able to achieve the following:
The treatment is often a surgical procedure and the best time for surgery is between 3 and 18 months of age . Generally, surgery is less traumatic when it is done early enough.
The main cause of this birth defect is not completely understood in majority of cases . However, treatment with progesterone during pregnancy may increase the risk of developing hypospadias. When there is hormonal fluctuation such as inability of the fetal testes to produce enough testosterone or the failure of the body to respond to produced testosterone this brings about an increase in the risk of hypospadias and other such genetic problems. Hypospadias may also be inherited.
The risk of infant males born to older women presenting hypospadias is high. The same is also the case with people who were conceived with in vitro fertilization (IVF). The connection to IVF may be due to the fact that such mothers are exposed to progesterone, a natural hormone or to progestin, which is a synthetic form of progesterone that is often administered during the IVF process.
In the United States, hypospadias is seen in 1 out of every 250 male births . The incidence in several countries is on the increase but figures are pegged at 0.26 per 1000 live births in Mexico and Scandinavia and 2.11 per 1000 live births in Hungary. The incidence of hypospadias is much higher in whites than in blacks and is seen mostly in people with Jewish or Italian heritage.
Even though the increase in incidence in many countries is believed to be as a result of increased reportage of minor grades of hypospadias, increases in severe hypospadias have equally been noted.
This condition cannot be prevented.
Hypospadias is a birth defect which affects anterior urethral and penile formation.  The condition is characterized by an opening of the urethra located ectopically on the penile ventrum. The glans penis in this condition is often split open. In some cases, the urethral opening may be located as far as the scrotum or perineum.
The penis in this case is more likely to have a chordee characterized by ventral shortening and curvature as well as other proximal urethral defects .
This condition was described as far back as the second century AD following the work of Galen who was also the first to use this term. Amputation of the penis, distal to the meatus was the primary treatment for the disease in the first millennium. All of this has changed with better diagnostic and therapeutic procedures obtainable today.
Hypospadias is a condition where the opening of the penis is under the penis or any other location instead of the tip as seen in normal people. The opening of the tip leads to the urethra which is responsible for conveying urine and seminal fluid.
The condition is often seen in newly born males and it is common. It doesn’t affect the child in other ways medically and doesn’t stop them from growing up normal except in serious cases with complications. Parents who do not want their child to grow up with this condition agree to surgical correction of the condition which is successful in most cases allowing the child to have a penis that is normal and allows general sexual function.