Symptoma

Hypothalamo-Pituitary Disorder

Hypothalamo Pituitary Disorder

At present, it is not clear whether the abnormalities are related to the affective episodes only or to the disorder itself. [ncbi.nlm.nih.gov]

(For microprolactinomas, the serum prolactin is not that high) Men present later, so usually have macroadenomas and present with non specific symptoms of low testosterone (depression, low libido) and may present with mass symptoms (e.g. [brainscape.com]

N Engl J Med 2011; 365:e46 A 23-year-old man presented with a 1-year history of diabetes mellitus, hypertension, and hypogonadism and a weight gain of 22 kg. Abdominal striae were present on physical examination (Panel A). [nejm.org]

Oxytocin is present in men but has no proven function. Click here for Patient Education NOTE: This is the Professional Version. [merckmanuals.com]

Hypertension is present in 40 % of patients with acromegaly, although its cause is unknown. [intranet.tdmu.edu.ua]

  • Short Stature in Children

    GH deficiency - short stature in children and reduced QoL in adults. Gonadotropin deficiency - loss of secondary sexual characteristics in adults and loss of periods is an early sign for women. [brainscape.com]

    stature in children When to see a doctor See your doctor if you develop signs and symptoms associated with hypopituitarism. [mayoclinic.org]

    stature (in children) Weakness Call your provider if you have: Headaches Symptoms of hormone excess or deficiency Vision problems If you have symptoms of a hormonal deficiency, discuss replacement therapy with your provider. [medlineplus.gov]

  • Thyroid Nodule

    nodule 3.5.4 Pathogenesis of thyroid cancer 3.5.5 Pathology of thyroid cancer 3.5.6 Papillary, follicular, and anaplastic thyroid carcinoma and lymphoma 3.5.7 Medullary thyroid carcinoma Part 4 Parathyroid, calcium, and bone metabolism 4.1 Parathyroid [oxfordmedicine.com]

  • Easy Bruising

    Round, pink face, round abdomen, skinny and weak limbs, thin skin and easy bruising, striae on abdomen. Other than features affecting appearance, what symptoms are there of Cushing's disease? High BP, diabetes and osteoporosis, 50% 5 year mortality. [brainscape.com]

  • Slow Pulse

    TSH and ACTH deficiency is a late feature of pituitary tumours - low thyroid hormones mean cold, weight gain, tiredness, slow pulse (low T4 for unraised TSH) and low cortisol means tired, dizzy, low BP, low Na . [brainscape.com]

  • Thin Skin

    Round, pink face, round abdomen, skinny and weak limbs, thin skin and easy bruising, striae on abdomen. Other than features affecting appearance, what symptoms are there of Cushing's disease? High BP, diabetes and osteoporosis, 50% 5 year mortality. [brainscape.com]

  • Large Hand

    Large hands and feet and increased subcutaneous tissue are evident on examination. Carpal tunnel syndrome occurs in as many as 44 % of the patients. [intranet.tdmu.edu.ua]

  • Neglect

    – Part 1: Strength – Chapter 5: The 5 Essential Elements of An Endurance Training Program That Most Athletes Neglect – Part 2: Power & Speed – Chapter 5: The 5 Essential Elements of An Endurance Training Program That Most Athletes Neglect – Part 3: Mobility [bengreenfieldfitness.com]

Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS). ‎ Seite 169 - Lepor H, Williford WO, Barry MJ, et al. [books.google.de]

Prolactinomas in men: Clinical characteristics and the effect of bromocriptine treatment. Acta Med. Scand. 217: 101–109. PubMed Google Scholar Lundberg, P. O., Drettner, B., Hemmingsson, A., Stenkvist, B., and Wide, L. (1977). [link.springer.com]

Tumours in the cavernous sinus need additional treatment. Medical treatment: reduce GH secretion - dopamine agonist and somatostatin analogues (octreotide, lanreotide etc) and block GH receptor - pegviosomant. [brainscape.com]

Continued Hypopituitary Treatment - Medical Treatment Medical treatment consists of hormone replacement therapy and treatment of the underlying cause. Medications Drugs used to treat hypopituitarism replace the deficient hormone. [webmd.com]

Some patients may receive treatment with GnRH, the hypothalamic hormone. In most cases, treatment will be based on the specific deficiency demonstrated. [medical-dictionary.thefreedictionary.com]

Prognosis The prognosis for most patients with hypopituitarism is excellent. As long as therapy is continued, many experience normal life spans. [medical-dictionary.thefreedictionary.com]

Outlook If hormone replacement therapy is adequate, the prognosis is good. Complications are often related to the underlying disease. For More Information Visit the Pituitary Network Association web site. [webmd.com]

The prognosis for obesity is poor, particularly for obese children, and the course tends to progress throughout the life. Obesity is a chronic condition resistant to treatment and prone to relapse. [intranet.tdmu.edu.ua]

Polycystic ovary syndrome: etiology and pathogenesis. Arch Gynecol Obstet. 274, 187 (2006) S. Jonard et al., The ovarian markers of the FSH insufficiency in functional hypothalamic amenorrhoea. Hum Reprod. 20, 101 (2005) C. [charite.de]

Etiology Children with pituitary dwarfism most commonly have either a craniopharyngioma or no demonstratable etiology (idiopathic hypopituitarism). The latter is more frequent in males than in females. [intranet.tdmu.edu.ua]

Serum levels of pituitary hormones are lower than normal. hypopituitarism Endocrinology A condition characterized by secretion of one or more anterior pituitary or adenohypophyseal hormones Etiology Idiopathic, pituitary tumor, hypothalamic or infundibular [medical-dictionary.thefreedictionary.com]

System Humans Huntington Disease Hydrocortisone Vasopressins Adult Aged Middle Aged Female Male General Science & Technology MD Multidisciplinary Publication Status: Published Article Number: ARTN e0138848 Appears in Collections: Faculty of Medicine Epidemiology [spiral.imperial.ac.uk]

[…] thyroid hormones 3.1.3 Clinical assessment of the thyroid patient 3.1.4 Thyroid function tests and the effects of drugs 3.1.5 Nonthyroidal illness 3.1.6 Thyroid imaging: nuclear medicine techniques 3.1.6.1 Thyroid imaging: nonisotopic techniques 3.1.7 Epidemiology [oxfordmedicine.com]

[…] biochemistry of nutrition 180 Nutritional disorders and their management 200 Clinical biochemistry of the gastrointestinal tract 214 Assessment of hepatic function and investigation of jaundice 231 Acute and chronic liver disease 250 Glucose metabolism and the pathophysiology [books.google.com]

The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders. Psychoneuroendocrinology, 25(1), 1-35. ‎ Pagina 52 - In: Wall PD, Melzack R (eds), Textbook of pain. Churchill Livingstone, Edinburgh... ‎ [books.google.it]

Hypothalamic dysfunction (hypothalamic syndromes) 2.4.2 Craniopharyngiomas 2.4.3 Perisellar tumours including cysts, hamartomas, and vascular tumours 2.4.4 Lymphocytic hypophysitis and other inflammatory conditions of the pituitary 2.5 Pineal physiology and pathophysiology [oxfordmedicine.com]

Indian J Endocr Metab 2 A clinical and pathophysiological approach to traumatic brain injury-induced pituitary dysfunction Sule Temizkan,Fahrettin Kelestimur Pituitary. 2019; 3 Traumatic brain injury induced neuroendocrine changes: acute hormonal changes [ijem.in]

"Neuroendocrinology and pathophysiology of the stress system." Annals of the New York Academy of Sciences 771.1 (1995): 1-18. Charmandari, Evangelia, Constantine Tsigos, and George Chrousos. "Endocrinology of the stress response 1." Annu. Rev. [mind-body-health.net]

Prevention of bone loss with alendronate in postmenopausal women under 60 years of age. ‎ Pagina 74 - Heim, C".., Ehlert, U., & Hellhammer, DH (2000). The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders. [books.google.it]

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Hormone blood tests can be taken randomly for some hormones, but others may require specialised testing with substances that should provoke the release or prevent release in certain conditions. [patient.info]

These hormones have an inhibitory effect on the pituitary and the hypothalamus, thereby preventing uncontrolled release of the pituitary hormones. This system is known as the parvicellular system. [endocrinesurgeon.co.uk]

Prevention There is no known prevention of hypopituitarism, except for prevention of damage to the pituitary/hypothalamic area from injury. Key terms Adenoma — A benign (not threatening or cancerous) tumor that originates in a gland. [medical-dictionary.thefreedictionary.com]