Symptoma

Hypotrichosis 8

Wooly Hair

Structural hair defects may be presented with a genetic disorder affecting hair growth or part of a congenital syndrome or may indicate underlying metabolic disorders, or may be associated with other diseases. [e-ijd.org]

Improve your interpretation of presenting symptoms with 38 new topics and 40 new images in the Differential Diagnosis section, and optimize patient care with more than 250 new figures and tables. [books.google.com]

The nine affected adults presented with sparse, thin and short hair. Somewhat less sparse and longer hair was observed in the two affected young children in the third generation. [doi.org]

We report two patients, mother and daughter, presenting a Marie Unna's syndrome and belonging to a family in which the disease appeared in seven members in a period of four generations. [moh-it.pure.elsevier.com]

EEM Syndrome Clinical Characteristics Ocular Features: Granular pigmentation and a grayish coloration of the retina may be present. [disorders.eyes.arizona.edu]

  • Turkish

    Novel mutations in the P2RY5 gene in one Turkish and two Indian patients presenting with hypotrichosis and woolly hair. Arch Dermatol Res 301, 621–4 (2009). 7. Jelani, M., Wasif, N., Ali, G., Chishti, M. & Ahmad, W. [nature.com]

    Pasternack SM, Murugusundram S, Eigelshoven S, Müller M, Kruse R, Lehmann P, Betz RC. (2009) Novel mutations in the P2RY5 gene in one Turkish and two Indian patients presenting with hypotrichosis and woolly hair. Arch. Dermatol. [guidetopharmacology.org]

  • Sparse Eyebrows

    In most cases body hair, axillary hair, and public hair were also sparse. Eyebrows, eyelashes, and beard hairs were not affected. Under light microscopy, the bulb portion of the plucked hair showed dystrophic features and was miniaturized. [omim.org]

    Ptosis, microcornea, congenital cataracts, sparse eyebrows, and strabismus are usually present. Epicanthal folds are often seen. Systemic Features: Psychomotor development is severely delayed and with delay or absence of milestones. [disorders.eyes.arizona.edu]

    Clinical features of affected individuals with this form of alopecia include: shedding of normal scalp hair several months after birth with failure to regrow; appearance of skin papules within the first year of life; sparse eyebrows and eyelashes; lack [jpma.org.pk]

    (E–G) Affected members III-2 and IV-6 (family A) and IV-13 (family C) showed woolly scalp hair/sparse scalp hair, sparse eyebrows and eyelashes. [journals.plos.org]

  • Sparse Eyelashes

    Sparse eyelashes MedGen UID: 375151 • Concept ID: C1843300 • Finding Decreased density/number of eyelashes. Sparse scalp hair MedGen UID: 346499 • Concept ID: C1857042 • Finding Decreased number of head hairs per unit area. [ncbi.nlm.nih.gov]

  • Dry Hair

    Dry hair MedGen UID: 75809 • Concept ID: C0277960 • Finding Hair that lacks the lustre (shine or gleam) of normal hair. [ncbi.nlm.nih.gov]

  • Thin Eyebrows

    Sparse and thin eyebrow MedGen UID: 371332 • Concept ID: C1832446 • Finding Decreased density/number and/or decreased diameter of eyebrow hairs. [ncbi.nlm.nih.gov]

  • Sparse Eyelashes

    Sparse eyelashes MedGen UID: 375151 • Concept ID: C1843300 • Finding Decreased density/number of eyelashes. Sparse scalp hair MedGen UID: 346499 • Concept ID: C1857042 • Finding Decreased number of head hairs per unit area. [ncbi.nlm.nih.gov]

  • Suggestibility

    Access full-color images and more than 90 online-only topics at Expert Consult, as well as EBMs, Suggested Reading, Patient Teaching Guides, and additional algorithms. [books.google.com]

    A phenotypic variation was observed amongst the family members and is suggestive of a reduced penetrance of the trait or the effect of a modifying factor. [doi.org]

    It may affect normal hair following excessive or repeated trauma, or may occur after minimal trauma if there is an inherent defect in keratin synthesis causing abnormally brittle hair. [5], [6] Blume-Peytavi U, et al. suggested the triad of hypotrichosis [e-ijd.org]

    Participating optometrists “volunteer their time […] Continue Reading March 9, 2009 Vigorous exercise may help prevent AMD, cataracts, studies suggest. [visionsource-drjack.com]

    Ultrasound of sacral region suggested a blind sinus. 2D Echo, brainstem enhanced response audiometry and MRI brain of child was normal. [casereports.in]

A consistent format makes it easy to locate information on each skin disorder, including a clinical description, its cause and pathogenesis, clinical features, clinical management, diagnosis, treatment, and any zoonotic aspects. [books.google.com]

[…] across all treatment groups. [journals.lww.com]

Treatment Treatment Options: No known treatment has been reported. [disorders.eyes.arizona.edu]

Treatment Unfortunately, there really is no treatment for most forms of hypotrichosis as they are genetic or congenital issues, which are often hard or impossible to treat. Some exceptions exist, however. [study.com]

LATISSE is a solution treatment for inadequate or not enough lashes and requires a prescription from a doctor. However, mascara can be used on your eyelashes in addition to LATISSE . 7. [theeyespecialists.com]

Further reading Lipase member H is a novel secreted protein associated with a poor prognosis for breast cancer patients Meizi Cui, Haofan Jin, Xiumin Shi, Ge Qu, Lidi Liu, Xiaobo Ding, Yanbo Wang & Chao Niu Tumor Biology (2014) A splice variant in KRT71 [nature.com]

We are reporting this case to focus on wide range of associated manifestations, early detection, optimum management and genetic counselling in view poor prognosis. [casereports.in]

Etiology Br J Dermatol 2017 Jan;176(1):138-144. Epub 2016 Dec 19 doi: 10.1111/bjd.14836. PMID: 27375176 Raykova D, Klar J, Azhar A, Khan TN, Malik NA, Iqbal M, Tariq M, Baig SM, Dahl N PLoS One 2014;9(4):e93607. [ncbi.nlm.nih.gov]

The etiology suggests that there could be poor absorption of other nutrients as well. [omicsonline.org]

Relevant External Links for LPAR6 Human Genome Epidemiology (HuGE) Navigator LPAR6 Atlas of Genetics and Cytogenetics in Oncology and Haematology: LPAR6 No data available for Genatlas for LPAR6 Gene Expression of purinergic receptors (ionotropic P2X1- [genecards.org]

Epidemiology [ edit ] It is estimated to affect less than one in a million people. [1] Only 50 to 100 cases have so far been described. [1] History [ edit ] The disease was first described in 1935 by Hans Wagner, a German physician. [2] References [ edit [en.wikipedia.org]

A powerful approach to advance our understanding of the pathophysiology of hair loss is to identify the genes underlying isolated and syndromic forms of hair loss. [jpma.org.pk]

Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.com]

Participating optometrists “volunteer their time […] Continue Reading March 9, 2009 Vigorous exercise may help prevent AMD, cataracts, studies suggest. [visionsource-drjack.com]

Lens opacification may be severe even early in life and requires prompt surgical intervention to prevent amblyopia. [disorders.eyes.arizona.edu]

Subjects with systemic diseases, including all types of alopecia areata, which could prevent hair growth or produce abnormal growth were excluded, along with subjects with substantial permanent eyebrow loss due to overgrooming; any skin pigmentation/depigmentation [journals.lww.com]