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Idiopathic Basal Ganglia Calcification Type 1
Primary Familial Brain Calcification Type 1

Presentation

Fahr's syndrome presenting with pure and progressive presenile dementia. Neurol Sci. 2005;26:367–9. [PubMed: 16388376] Morita M, Tsuge I, Matsuoka H, Ito Y, Itosu T, Yamamoto M, Morishima T. [ncbi.nlm.nih.gov]

Treatment

Treatment Treatment There is no standard course of treatment for PFBC. Treatment typically addresses symptoms on an individual basis. Medications may be used to improve anxiety, depression, obsessive-compulsive behaviors, and dystonia. [rarediseases.info.nih.gov]

Prognosis

Surveillance typically includes yearly neurologic and neuropsychiatric assessments.[1] Last updated: 9/4/2015 Prognosis Prognosis The prognosis for any individual with PFBC is variable and hard to predict. [rarediseases.info.nih.gov]

Prevention

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation. Nature. 2015;517:89–93. [PMC free article: PMC4303590] [PubMed: 25307056] [ncbi.nlm.nih.gov]

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