Moreover, dialysis was associated with features of immune senescence, including: CD4+ T cell lymphopenia, reduced thymic output, terminally differentiated CD8+ T cell expansion driven by CMV and telomere length shortening. [theses.fr]

Criteria for the case definition are: 1) CD4 cell count less than 300/mm3 or a CD4 percent less than 20% on two or more measurements; 2) lack of laboratory evidence of HIV infection; and 3) absence of alternative explanation for the CD4 cell lymphopenia [btb.termiumplus.gc.ca]