Idiopathic hypersomnia and Kleine–Levin syndrome have attracted much interest in recent years, and an overview of recent progresses is presented in this chapter. [oxfordmedicine.com]

S...Sforza E 2011 40 Presentations of primary hypersomnia in Chinese children. ( 21532956 ) Han F...Mignot E 2011 41 Effect of levothyroxine on prolonged nocturnal sleep time and excessive daytime somnolence in patients with idiopathic hypersomnia. [malacards.org]

However, the influence of exogenous factors on the observations of the present study can be ruled out due to identical incubation conditions. [frontiersin.org]

Bruxism is present frequently during sleep. Men and women are affected equally. Obesity is uncommon in this condition. [beatcfsandfms.org]

• Fatigue

  'Excessive daytime sleepiness', 'hypersomnia' in the sense of prolonged sleep need, 'tiredness' or 'fatigue' are frequent complaints in primary care, requiring a careful separation in view of a correct diagnostic. [ncbi.nlm.nih.gov]

  […] is characterized by persistent or relapsing fatigue that does not resolve with bed rest. [beatcfsandfms.org]

Getting Closer to Certainty in Idiopathic Hypersomnia Diagnosis. ( 30952230 ) Trotti LM 2019 4 Update on treatment for idiopathic hypersomnia. ( 29250981 ) Evangelista E...Dauvilliers Y 2018 5 Alternative diagnostic criteria for idiopathic hypersomnia [malacards.org]

Similar to that of narcolepsy Treatment of idiopathic hyperinsomnia is similar to that of narcolepsy (eg, modafinil), except that anticataplectic drugs are unnecessary. Click here for Patient Education NOTE: This is the Professional Version. [msdmanuals.com]

Similar to that of narcolepsy Treatment of idiopathic hyperinsomnia is similar to that of narcolepsy (eg, modafinil), except that anticataplectic drugs are unnecessary. [merckmanuals.com]

[…] day -- even while at work, or during a meal or conversation Increased sleep time -- up to 14 to 18 hours a day Other symptoms may include: Anxiety Feeling irritated Loss of appetite Low energy Restlessness Slow thinking or speech Trouble remembering Treatment [account.allinahealth.org]

Google Scholar | Medline Ali M., Auger RR, Slocumb NL, Morgenthaler TI Idiopathic hypersomnia: clinical features and response to treatment. J Clin Sleep Med. 2009 ;15: 562 - 568. Google Scholar Nevšímalová S., Blažejová K., Illnerová H., et al. [journals.sagepub.com]

IH is a primary sleep disorder of not yet finally resolved etiology characterized by a high and disabling amount of sleep required during the day, despite normal or even prolonged sleep times at night. [frontiersin.org]

No current reliable epidemiological data are available due to a lack of any clinical observational studies. [frontiersin.org]

A contribution to pathophysiology of idiopathic hypersomnia. Clin Neurophysiol. 2000 ;53(suppl): 366 - 370. Google Scholar Sforza E., Gaudreau H., Petit D., Montplaisir J. Homeostatic sleep regulation in patients with idiopathic hypersomnia. [journals.sagepub.com]

Apart from genetic factors, an enhanced activity of a GABA A -receptor stimulating-factor could be detected in vitro in the CSF of IH patients that could also contribute to the pathophysiological mechanism of these patients ( 10 ). [frontiersin.org]

PATHOPHYSIOLOGY In contrast with narcolepsy, no animal model of idiopathic hypersomnia is available; thus, experimental approaches are limited. [beatcfsandfms.org]

Lifestyle changes that can help ease symptoms and prevent injury include: Avoid alcohol and medicines that can make the condition worse Avoid operating motor vehicles or using dangerous equipment Avoid working at night or social activities that delay [account.allinahealth.org]