Presentation
The majority of children with IH are asymptomatic; however, the most common clinical presentation is that of isolated hematuria (gross or microscopic). The prevalence, presentation and clinical course of IH is less well established in infants. [ncbi.nlm.nih.gov]
Entire Body System
- Asymptomatic
Hypercalciuria and reduced BMD were uncovered in a substantial number of their otherwise healthy asymptomatic mothers. [ncbi.nlm.nih.gov]
Cardiovascular
- Hypertension
Seven low calcium intake participants withdrew because of hypertension ‐ a possible adverse effect of low calcium intake. [cochranelibrary.com]
Urogenital
- Kidney Failure
Although kidney stones are not a significant cause of kidney failure, epidemiological data suggest that most people who develop kidney stones have mildly compromised kidney function (Gillen 2005). [cochranelibrary.com]
Workup
X-Ray
- Nephrolithiasis
METHODS: Seventy patients with calcium nephrolithiasis and idiopathic hypercalciuria, 19 to 64 years old, were assessed for spine and femur mineral metabolism and bone density using a Dexa evaluation system. [ncbi.nlm.nih.gov]
Treatment
The BMD z-score of the patients improved with treatment, suggesting a beneficial effect and potential need for treatment. However, the lack of a control group points to the need for future studies to corroborate this outcome. [ncbi.nlm.nih.gov]
Prognosis
No association was found between IHC and the recurrence of UTI, presence of vesicoureteral reflux, renal scar formation, and the prognosis. [ncbi.nlm.nih.gov]
Etiology
The aim of this review is to delineate our current understanding of idiopathic hypercalciuria in the context of bone health, specifically its definition, etiology, epidemiology, laboratory evaluation, and potential therapeutic management. [ncbi.nlm.nih.gov]
Language French Keyword (fr) LITHIASE REIN CALCUL CALCIQUE HYPERCALCIURIE IDIOPATHIQUE ETIOLOGIE METABOLISME PATHOLOGIE ELEMENT MINERAL HOMME PATHOLOGIE URINAIRE MALADIES METABOLIQUES Keyword (en) LITHIASIS KIDNEY CALCIUM CALCULUS HYPERCALCIURIA IDIOPATHIC ETIOLOGY [pascal-francis.inist.fr]
Epidemiology
The aim of this review is to delineate our current understanding of idiopathic hypercalciuria in the context of bone health, specifically its definition, causes, epidemiology, laboratory evaluation, and potential treatments. [ncbi.nlm.nih.gov]
Although kidney stones are not a significant cause of kidney failure, epidemiological data suggest that most people who develop kidney stones have mildly compromised kidney function (Gillen 2005). [cochranelibrary.com]
Pathophysiology
The potential pathogenic mechanisms are discussed, and the limits of the classical Pak's pathophysiological classification are recalled. [ncbi.nlm.nih.gov]
Although hypercalciuria is thought to be related to osteopenia and osteoporosis, the pathophysiological mechanisms of bone loss are unknown. [cochranelibrary.com]
Prevention
CONCLUSION: On the basis of these results, we reject the hypothesis that treating hypercalciuria is beneficial in preventing repeated UTIs. [ncbi.nlm.nih.gov]