Presentation
UCTD was considered present when serum autoantibodies were present and symptoms or signs suggested CTD. The relationship between UCTD and NSIP histology was evaluated. [ncbi.nlm.nih.gov]
Workup
Studies have shown that cryobiopsy can provide a definitive diagnosis in many patients undergoing workup for IIP, eliminating the need for surgical lung biopsy. [clinicaladvisor.com]
It is possible that bronchiolocentric interstitial pneumonia represents a form of chronic hypersensitivity pneumonitis for which the inhalational stimulus has not been identified despite our extensive workup for this condition. [nature.com]
See Workup for more detail. Management The optimal medical therapy for the treatment of idiopathic pulmonary fibrosis has yet to be identified. [emedicine.medscape.com]
Microbiology
- Human Herpesvirus 6
In all four patients, (1) the conditioning regimen induced total body irradiation, (2) serological reactivation of cytomegalovirus and/or human herpesvirus-6 preceded the onset of IIP, (3) their human leucocyte antigen types were among those suspected [ncbi.nlm.nih.gov]
Other Pathologies
- Lymphocytic Infiltrate
Desai SR, Nicholson AG, Stewart S et al. (1997) Benign pulmonary lymphocytic infiltration and amyloidosis: computed tomographic and pathologic features in three cases. J Thorac Imag 12: 215–220 Google Scholar 10. [link.springer.com]
Histopathology of RB-ILD RB-ILD is characterized by pigmented macrophages within respiratory bronchioles accompanied by submucosal and peribronchial cellular infiltrates (lymphocytes and histiocytes). [clinicaladvisor.com]
An increase in either or both lymphocytes and granulocytes can be seen [ 75 – 78 ]. Overall, lymphocytes appear to be a more prominent feature in rheumatoid arthritis than in systemic sclerosis. [err.ersjournals.com]
Treatment
Although pulmonary (67)Ga uptake significantly decreased after treatment (P = 0.001), there was no correlation between either initial (67)Ga uptake or change in (67)Ga uptake on treatment and 1-y prognosis. [ncbi.nlm.nih.gov]
steroids Associations: Sjögren, AIDS Treatment: smoking cessation Mortality 30% at 10 yearsTreatment: ventilation/steroids Multiple basal predominant Treatment: steroids Upper lung predominant faint Treatment: smoking cessationDiffuse symmetric basal [slideshare.net]
Novel treatments (pirfenidone and nintedanib) are available but choice of treatment, duration and impact on a real life scale are unknown. 6 Classification of IIPs (ATS/ERS 2013) 3 References: Travis WD, Costabel U, Hansell DM, King TE, Lynch DA. [swissiip.ch]
There are several treatment options for idiopathic interstitial pneumonia and sometimes the treatment depends on which type the patient has. Steroid treatment is often used. [myvmc.com]
Prognosis
In patients with IPF or fibrotic NSIP, pulmonary (67)Ga scintigraphy may be useful for predicting response to therapy and prognosis. [ncbi.nlm.nih.gov]
Predicting prognosis in the individual patient is challenging but various clinical and radiologic variables have been identified. [doi.org]
Etiology
As the name implies, the etiology is unknown. In the more severe forms of IIP, such as idiopathic pulmonary fibrosis and acute interstitial pneumonia, no effective therapies have been identified. [ncbi.nlm.nih.gov]
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
[…] such as connective tissue diseases and hypersensitivity pneumonia IPF was previously called chronic interstitial pneumonitis or cryptogenic fibrosing alveolitis Sites Bottom of lower lobes of bilateral (or "bibasilar") lung Pathophysiology / etiology [pathologyoutlines.com]
Epidemiology
SETTING: Although the incidence and prevalence of idiopathic interstitial pneumonia (IIP) and idiopathic pulmonary fibrosis (IPF) have been assessed in Western countries, their epidemiology has not been analysed in Asian countries, including the Republic [ncbi.nlm.nih.gov]
Jump to: navigation, search Idiopathic Interstitial Pneumonia Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Idiopathic interstitial pneumonia from other Diseases Epidemiology [wikidoc.org]
COP: Epidemiology and outcomes The initial name of COP was bronchiolitis obliterans with organizing pneumonia (“BOOP”). [clinicaladvisor.com]
Idiopathic Interstitial Pneumonia Aka: Idiopathic Pulmonary Fibrosis, Usual Interstitial Pneumonia, Desquamative Interstitial Pneumonia, Respiratory Bronchiolitis, RB-ILD, Acute Interstitial Pneumonia, Hamman-Rich Disease, Nonspecific Interstitial Pneumonia Epidemiology [66.199.228.237]
Contents Complications and Discontinuation 339 Oxygen Therapy and Toxicity 345 ProtocolDriven Care in Respiratory Therapy 351 Epidemiology Natural History 357 Prophylaxis 364 Chronic Thromboembolic Pulmonary Hypertension 375 Unusual Forms of Embolism [books.google.com]
Pathophysiology
New insight into the pathophysiology of idiopathic pulmonary fibrosis suggests a distinctly fibroproliferative process, and antifibrotic therapies show promise. [ncbi.nlm.nih.gov]
Jump to: navigation, search Idiopathic Interstitial Pneumonia Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Idiopathic interstitial pneumonia from other Diseases Epidemiology [wikidoc.org]
Prevention
Since IP itself is likely a risk factor for PP, prevention of BPF is important for patients with IP, as it can lead to PP. [ncbi.nlm.nih.gov]
Prevention of bacterial endocarditis. Page 303 - American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. [books.google.com]
Prevention The following measures may help you prevent hyponatremia: Treat associated conditions. Getting treatment for conditions that contribute to hyponatremia, such as adrenal gland insufficiency, can help prevent low blood sodium. [mayoclinic.org]
Can interstitial lung disease be prevented? Interstitial lung disease can be prevented only to the extent that its individual causes may be prevented. [medicinenet.com]