Knee and ankle pain, kyphosis, loss of height and a sunken chest may also be present. Low bone mineral density, vertebral collapse and metaphyseal compression fractures of the long bones are common. [orpha.net]

Here, the authors present a representative case of this rare disorder in an otherwise healthy male, along with the clinical history, physical presentation, and review of the available literature. [ncbi.nlm.nih.gov]

The present paper reports two cases of this condition and reviews the literature. [experts.umich.edu]

• Aspiration

  Bone marrow aspirate revealed normal cellularity, bone biopsy showed diminished number and thickness of bone trabeculae. [bone-abstracts.org]

• Osteoporosis

  juvenile osteoporosis Idiopathic osteoporosis OSTEOPOROSIS, JUVENILE Idiopathic Juvenile Osteoporosis IJO edit English idiopathic juvenile osteoporosis osteoporosis with no known cause that is characterized by pain in the back and extremities, walking [wikidata.org]

  Juvenile osteoporosis is osteoporosis in children and adolescents. Osteoporosis is rare in children and adolescents. [en.wikipedia.org]

  Secondary osteoporosis Idiopathic juvenile osteoporosis Distinguishing juvenile Osteoporosis from osteogenesis imperfecta For your information Secondary osteoporosis Secondary osteoporosis, which can affect both adults and children, results from another [niams.nih.gov]

  A MEDLINE search was performed of the following terms: idiopathic juvenile osteoporosis, pediatric osteoporosis, adolescent osteoporosis, bisphosphonates pediatric adolescent, and pregnancy osteoporosis, and references from bibliographies of selected [ncbi.nlm.nih.gov]

Gynecologists, Family Physicians After completion of this article, the reader will be able to describe the condition idiopathic juvenile osteoporosis, compare the clinical features of this condition to other similar conditions, outline the diagnostic workup [ncbi.nlm.nih.gov]

A case report is presented and current methods of diagnosis and treatment of IJO are discussed as well as the differential diagnosis. [ncbi.nlm.nih.gov]

There is no established treatment strategy. Treatments with calcium and/or vitamin D, fluoride, calcitonin, and bisphosphonates (in severe, long-lasting cases) have been reported with unequivocal efficacy. [orpha.net]

The results of treatment with a Milwaukee brace in one case have been particularly gratifying and would indicate that brace treatment should be considered when this condition is encountered. [experts.umich.edu]

Treatment for pediatric osteoporosis Specific treatment for pediatric osteoporosis will be determined by your child's doctor based on: Your child's age, overall health, and medical history Extent of the disease Your child's tolerance for specific medications [stanfordchildrens.org]

Prognosis The disease is self-limiting with spontaneous resolution after the onset of puberty. Rarely, in more severe cases, permanent disability (kyphoscoliosis and rib deformity) can develop. [orpha.net]

Diagnosis - Juvenile osteoporosis Prognosis - Juvenile osteoporosis Most children with IJO experience a complete recovery of bone tissue. [checkorphan.org]

Key words Osteoporosis Idiopathic Prepubertal Self-limiting Variable prognosis This is a preview of subscription content, log in to check access. Preview Unable to display preview. Download preview PDF. References 1. [link.springer.com]

Etiology The etiology of idiopathic juvenile osteoporosis remains unknown. [orpha.net]

Diagnostic studies are usually oriented to rule out neuromuscular etiologies or, once organic causes have been reasonably discarded, conversion disorders. [ncbi.nlm.nih.gov]

Summary Epidemiology The exact prevalence is unknown but several hundreds of cases have been reported in the literature so far. Clinical description Onset usually occurs in the prepubertal period, between 8 and 12 years of age. [orpha.net]

Epidemiology Osteoporosis generally has been considered an adult disease, but there is increasing evidence that its roots lie in childhood. [pedsinreview.aappublications.org]

Oen KG, Cheang M (1996) Epidemiology of chronic arthritis in childhood. Semin Arthritis Rheum 26(3):575–591 CrossRef PubMed 5. [springermedizin.at]

Its etiology and pathophysiology are not well understood and its diagnosis remains one of exclusion. [ped-rheum.biomedcentral.com]

It is also important to note that BMD is derived from an areal measure, defined as the bone mineral content (BMC) in grams per selected bone area measured in centimeters squared (see Pathophysiology below). [emedicine.medscape.com]

Chapurlat RD, Gensburger D, Jimenez-Andrade JM, Ghilardi JR, Kelly M, Mantyh P: Pathophysiology and medical treatment of pain in fibrous dysplasia of bone. Orphanet J Rare Dis 201;7(suppl 1):S3-S9. [karger.com]

Cooper, MD, AAOS Springer Publishing Company, ١٩‏/١٠‏/٢٠٠٧ - 280 من الصفحات Osteoporosis is a preventable disease. [books.google.com]

Some treatments that may be effective include physical therapy, medications to manage symptoms of the disease, and protective measures to help prevent fracture. [reliawire.com]

Is osteoporosis preventable? My mother had osteoporosis and I already have osteopenia which may lead to it. How can I prevent it?? A. [medical-dictionary.thefreedictionary.com]

Prevent falls Learn ways to prevent falls that might result in broken bones. Have your vision and hearing checked regularly. Wear slippers or shoes that have non-skid soles. [healthlinkbc.ca]

RANK ligand (RANKL) inhibitor A substance which prevents key proteins in the body from breaking down bone cells. When this happens, osteoclast activity is prevented which reduces bone resorption. This results in increased bone density. [nof.org]