Assessment of these factors thus allows the pathologist to make a relevant statement concerning the probable course and prognosis of the disease at the time of the diagnostic biopsy. [ncbi.nlm.nih.gov]

The fact that both brothers had identical HLA antigens suggests a genetic predisposing background. [ncbi.nlm.nih.gov]

Symptoms and Signs Patients typically present with edema and nephrotic-range proteinuria and occasionally with microscopic hematuria and hypertension. Symptoms and signs of a disorder causing MN (eg, a cancer) may be present initially. [merckmanuals.com]

Moreover, adults show an increased incidence of atypical clinical features such as hypertension, renal function impairment, non-selective proteinuria and microscopic hematuria 2, 3. [revistanefrologia.com]

Mild microscopic hematuria may be present in MN (both primary and secondary). A 24 hour urine collection should be obtained to quantify the amount of proteinuria. [renalandurologynews.com]

Severe hypoproteinemia (albumin 3.5 g/l) in 30 (41.1%), microscopic hematuria in 15 (20.5%), accompanying hypertension in 23 (31.5%), and eGFR 2 at the time of renal biopsy in 26 (35.6%) patients. [spandidos-publications.com]

The presence of microscopic hematuria is common (30 to 40%), but macroscopic hematuria and red cell casts are rare and suggest a different diagnosis ( 13 ). [cjasn.asnjournals.org]

For this study biopsies containing less than 10 nonsclerotic glomeruli were neglected. Immunofluorescence microscopy Tissue was snap frozen, sectioned at 5 µ and fixed in 95% alcohol for 10 min. [revistanefrologia.com]

The patients (six male, four female, mean age 50 years) were monitored over 9-30 months during which time creatinine clearance reduced from (mean /- SEM) 83 /- 10 to 29 /- 6 ml/min, and plasma creatinine increased from 135 /- 22 to 297 /- 35 mumol/l. [ncbi.nlm.nih.gov]