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Idiopathic Recurrent and Disabling Cutaneous Herpes

Presentation

Many patients present with café au lait spots, which, in most individuals, are present at birth. [emedicine.medscape.com]

A 35 year old white woman presented in March 2000 to a genitourinary medicine (GUM) clinic with 5 year history of recurrent lesions typical of genital herpes simplex virus (HSV) infection occurring almost every month. [sti.bmj.com]

Respiratoric

  • Pneumonia

    Anti-I antibodies primarily occur with idiopathic disease, with some lymphomas, and with mycoplasmal pneumonia. Anti-I–specific antibodies are associated with infectious mononucleosis and with some lymphomas. [emedicine.medscape.com]

Cardiovascular

  • Hypertension

    The most common causes of splenomegaly include portal hypertension caused by liver disease or splenic infiltration either with tumor cells (eg, in lymphoma) or by macrophages in storage diseases (eg, Gaucher disease). [emedicine.medscape.com]

  • Thrombosis

    venous thrombosis, recurrent fetal loss, and thrombocytopenia. [emedicine.medscape.com]

Skin

  • Papule

    The cutaneous eruption consists of erythematous-to-violaceous tender papules, which enlarge to form plaques with an irregular pseudovesicular surface. [51] The skin lesions are usually edematous, beefy, red papules or plaques. [emedicine.medscape.com]

Treatment

Excluding the infection by using cultures is critical before treatment is instituted. Corticosteroids remain the treatment of choice. In patients with underlying hematologic malignancies, topical treatment is generally not effective. [emedicine.medscape.com]

This case demonstrates the importance of early recognition of urticaria associated with HSV infections in order to avoid delay in instituting antiviral treatment in GUM clinics or other settings for this disabling skin condition. [sti.bmj.com]

Given the rarity of these diseases, the treatments outlined in the abstracts are not always evidence based. The information in the abstracts isnot intended to replace existing local, regional or country specific recommendations and guidelines. [orpha.net]

Also, in recent years, effective forms of treatment for several peripheral neuropathies have been introduced, making accurate diagnosis imperative. [accessmedicine.mhmedical.com]

Prognosis

The prognosis for leukemia cutis is related directly to the prognosis for the systemic disease. Therapy is usually directed at the underlying leukemia. [emedicine.medscape.com]

PATOLOGIA NEOPLASTICA min. max. fisso 9322 NEOPLASIE A PROGNOSI FAVOREVOLE CON MODESTA COMPROMISSIONE FUNZIONALE / / 11 9323 NEOPLASIE A PROGNOSI FAVOREVOLE CON GRAVE COMPROMISSIONE FUNZIONALE / / 70 9325 NEOPLASIE A PROGNOSI INFAUSTA O PROBABILMENTE [medisoc.it]

Etiology

They are organised into groups, and further divided into clinical, etiological or histopathological sub-types. [orpha.net]

Warfarin also has been implicated in the etiology of calciphylaxis in patients with end-stage renal disease. It is a poorly understood disorder associated with high morbidity and mortality (60-80%). [emedicine.medscape.com]

Epidemiology

Based on clinical experience and epidemiologic studies, the causes of leg ulceration can be divided into 3 categories: reduction in blood supply to the skin (infarction being the primary cause), local edema, and minor trauma. [emedicine.medscape.com]

Prevention

The goal of treatment in idiopathic thrombocytopenic purpura is to elevate the platelet count to a level adequate to prevent major bleeding. [emedicine.medscape.com]

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