Many patients present with café au lait spots, which, in most individuals, are present at birth. [emedicine.medscape.com]

A 35 year old white woman presented in March 2000 to a genitourinary medicine (GUM) clinic with 5 year history of recurrent lesions typical of genital herpes simplex virus (HSV) infection occurring almost every month. [sti.bmj.com]

• Arthritis

  AA-type amyloidosis (secondary systemic amyloidosis) is usually associated with a chronic inflammatory process, such as rheumatoid arthritis, chronic osteomyelitis, tuberculosis, or leprosy. [emedicine.medscape.com]

• Alopecia

  Several nonspecific lesions, including amyloidosis, cold urticaria, alopecia, pigmentation, and Raynaud phenomenon, are associated with multiple myeloma. [emedicine.medscape.com]

Excluding the infection by using cultures is critical before treatment is instituted. Corticosteroids remain the treatment of choice. In patients with underlying hematologic malignancies, topical treatment is generally not effective. [emedicine.medscape.com]

This case demonstrates the importance of early recognition of urticaria associated with HSV infections in order to avoid delay in instituting antiviral treatment in GUM clinics or other settings for this disabling skin condition. [sti.bmj.com]

Given the rarity of these diseases, the treatments outlined in the abstracts are not always evidence based. The information in the abstracts isnot intended to replace existing local, regional or country specific recommendations and guidelines. [orpha.net]

Also, in recent years, effective forms of treatment for several peripheral neuropathies have been introduced, making accurate diagnosis imperative. [accessmedicine.mhmedical.com]

The prognosis for leukemia cutis is related directly to the prognosis for the systemic disease. Therapy is usually directed at the underlying leukemia. [emedicine.medscape.com]

They are organised into groups, and further divided into clinical, etiological or histopathological sub-types. [orpha.net]

Warfarin also has been implicated in the etiology of calciphylaxis in patients with end-stage renal disease. It is a poorly understood disorder associated with high morbidity and mortality (60-80%). [emedicine.medscape.com]

Based on clinical experience and epidemiologic studies, the causes of leg ulceration can be divided into 3 categories: reduction in blood supply to the skin (infarction being the primary cause), local edema, and minor trauma. [emedicine.medscape.com]

The goal of treatment in idiopathic thrombocytopenic purpura is to elevate the platelet count to a level adequate to prevent major bleeding. [emedicine.medscape.com]