Presentation
Recurrence was documented in patients who presented typical chest pain and 1 or more of the following signs: fever, rubs, electrocardiographic changes, pericardial effusion, increase of acute phase reactants. [ped-rheum.biomedcentral.com]
Case Presentation: Here, we describe a 34 year-old female admitted with five days of worsening left sided pleuritic chest pain and shortness of breath. [shmabstracts.com]
Introduction Case Presentation: A 56-year-old previously healthy man presented with 2 days of pleuritic left anterior chest pain, lessened by sitting forward. [ahajournals.org]
[…] receptor antagonist, has been successfully used in small series of paediatric patients 8, 9 while we have recently first reported its efficacy and safety in three adult patients. 10 In this report, we extend our follow-up on these three patients, and present [ard.bmj.com]
Entire Body System
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Recurrent Inflammation
inflammation in these patients. [acc.org]
Respiratoric
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Recurrent Chest Pain
Launbjerg J, Fruergaard P, Hesse B, Jørgensen F, Elsborg L, Petri A (1996) Long-term risk of death, cardiac events and recurrent chest pain in patients with acute chest pain of different origin. Cardiology 87:235–240 CrossRef 2. [springermedizin.de]
Launbjerg J, Fruergaard P, Hesse B, Jørgensen F, Elsborg L, Petri A (1996) Long-term risk of death, cardiac events and recurrent chest pain in patients with acute chest pain of different origin. Cardiology 87:235–240 CrossRef Google Scholar 2. [link.springer.com]
Proposed diagnostic criteria for recurrent pericarditis include recurrent chest pain and 1 or more of the following signs: fever, pericardial friction rubs, electrocardiographic changes, echocardiographic evidence of new or worsening pericardial effusion [revespcardiol.org]
Cardiovascular
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Left Ventricular Dysfunction
After a mean follow-up of 61 months, the complication rate was 3.5% cardiac tamponade and 0% constrictive pericarditis and left ventricular dysfunction. [ncbi.nlm.nih.gov]
Eyes
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Dry Eyes
Possible noninvasive clues for autoimmunity are antinuclear (3) or antiheart (4) antibodies (50% of adults), dry eyes, arthralgias, and a subacute course. [onlinejacc.org]
Workup
Similar negative workup occurs in approximately 80% of all cases. [shmabstracts.com]
The objective of this article is to review the etiology, workup, and treatment for this disease, especially new, emerging therapeutic options. [dovepress.com]
Treatment
Colchicine is the standard treatment for FMF, while patients with TRAPS do not respond to colchicine therapy, but are responsive to corticosteroids. [ncbi.nlm.nih.gov]
Prognosis
The overall life prognosis is excellent in idiopathic recurrent pericarditis and complications are uncommon. [ncbi.nlm.nih.gov]
( 19116906 ) Picco P....Martini A. 2009 25 Idiopathic recurrent pericarditis refractory to colchicine treatment can reveal tumor necrosis factor receptor-associated periodic syndrome. ( 20074469 ) Cantarini L....Galeazzi M. 2009 26 Prognosis of idiopathic [malacards.org]
Prevalence of C-reactive protein elevation and time course of normalization in acute pericarditis: implications for the diagnosis, therapy, and prognosis of pericarditis. Circulation, 2011. 123(10): p. 1092-7. [acc.org]
Indicators of poor prognosis of acute pericarditis. Circulation. 2007 ; 115 :2739–2744. Link Google Scholar 7. Schifferdecker B, Spodick DH. Nonsteroidal anti-inflammatory drugs in the treatment of pericarditis. Cardiol Rev. 2003 ; 11 :211–217. [ahajournals.org]
Etiology
In developed countries, the idiopathic form is the most frequent, and the search for an infectious etiology is almost invariably negative. [ncbi.nlm.nih.gov]
Conclusions: The underlying etiology of idiopathic recurrent acute pericarditis remains controversial, as it may be a cross of infectious, autoimmune, or autoinflammatory etiologies. [shmabstracts.com]
Epidemiology
[…] antibiotics to treat tuberculosis or other bacterial causes. steroids are used in acute pericarditis but are not favored because they increase the chance of recurrent pericarditis. in rare cases, surgery in cases of constrictive pericarditis, pericardiectomy Epidemiology [en.wikipedia.org]
“Hypoparathyroidism in the adult: epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research.” J Bone Miner Res, 2011, 26: 2317-2337. [pubs.sciepub.com]
Pathophysiology
We herein review the current available reports regarding the evidence regarding the pathophysiology and reported cases and case series of IRP cases managed with immunomodulation therapy. Copyright 2016 Elsevier Inc. All rights reserved. [ncbi.nlm.nih.gov]
Masters SL, Simon A, Aksentijevich I, Kastner DL (2009) Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease. Annu Rev Immunol 27:621–668 PubMed CrossRef 29. [springermedizin.de]
We herein review the current available reports regarding the evidence regarding the pathophysiology and reported cases and case series of IRP cases managed with immunomodulation therapy. [thoracickey.com]
Masters SL, Simon A, Aksentijevich I, Kastner DL (2009) Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease. Annu Rev Immunol 27:621–668 PubMed CrossRef Google Scholar 29. [link.springer.com]
Prevention
Therapeutic strategies are not standardised, non-steroidal anti-inflammatory drugs at high dosages being the mainstay of therapy with the possible addition of low dose colchicine to prevent recurrences. [ncbi.nlm.nih.gov]
With prolonged corticosteroid use, osteoporosis prevention (eg, calcium, vitamin D, and bisphosphonates) should be considered. [ahajournals.org]