Symptomatic voiding dysfunction was present in 27 of the 30 patients (90 %). [ncbi.nlm.nih.gov]

• Nightmare

  See physician always: chest pain, difficulty urinating, nightmares, ringing in the ears, rapid heart rate excessive sedation or uncoordinated movements while taking this medication. [psyweb.com]

  Central nervous system: dizziness, drowsiness, confusion, seizures, headache, anxiety, tremors, stimulation, weakness, insomnia, nightmares, extrapyramidal symptoms in geriatric patients, increased psychiatric symptoms, paresthesia Cardiovascular: orthostatic [en.wikipedia.org]

  Tell your doctor if any of these symptoms are severe or do not go away: nausea drowsiness weakness or tiredness excitement or anxiety nightmares dry mouth skin more sensitive to sunlight than usual changes in appetite or weight constipation difficulty [medlineplus.gov]

  Less frequent side effects include: Seizures Ringing in the ears Abnormal movements and muscle rigidity Confusion Hallucinations Disorientation, delusions Anxiety Agitation Nightmares Memory loss Aggressiveness Heart rhythm problems, palpitations, fainting [anti-depressants.com]

  Side Effects of Imipramine Common side effects include: nausea drowsiness weakness or tiredness excitement or anxiety confusion nightmares dry mouth sun sensitivity weight loss or gain constipation difficulty urinating frequent urination blurred vision [rxwiki.com]

• Unconsciousness

  After a short period of time, she became unconscious and experienced hypotension and refractory arrhythmia, finally being diagnosed with imipramine poisoning. [ncbi.nlm.nih.gov]

• Nausea

  Other symptoms include stiff muscles, seizures, nausea, vomiting, diarrhea, and tremors (uncontrollable movements in one part of your body). If you have any of these symptoms, call your doctor right away. [healthline.com]

  If you have nausea, eye pain, changes in vision, such as seeing colored rings around lights, and swelling or redness in or around the eye, call your doctor or get emergency medical treatment right away. [medlineplus.gov]

  Common side effects include nausea, weakness and dry mouth. Imipramine can cause drowsiness and dizziness. Do not drive or operate heavy machinery until you know how it affects you. [rxwiki.com]

  Secondary Outcome Measures : Individual dyspeptic symptom scores [ Time Frame: 12 weeks ] 8-item dyspepsia symptom score questionnaire assessing epigastric pain, epigastric burning, postprandial fullness, early satiety, belching, bloating, nausea, and [clinicaltrials.gov]

• Abdominal Pain

  Improvements in bowel symptom severity rating for interference (P = 0.05) and distress (P = 0.02) were greater with imipramine versus placebo, but improvements in abdominal pain were not. [ncbi.nlm.nih.gov]

  TCAs have been shown to improve abdominal pain in patients with IBS; however, there is insufficient evidence of global symptom relief. The search for an optimal treatment to improve symptoms and quality of life in IBS remains ongoing. [news-medical.net]

  Irritable Bowel Syndrome (IBS) Irritable bowel syndrome (IBS) is a GI (gastrointestinal) disorder with signs and symptoms that include abdominal pain, bloating,... [medicinenet.com]

  Too much colchicine in the body leads to toxicity such as fever, vomiting, diarrhea, abdominal pain and muscle pains. [worstpills.org]

• Tachycardia

  Electrocardiography (ECG) showed tachycardia and widened QRS. He was immediately treated with bicarbonate infusion and made an uneventful recovery. This is the youngest and only reported case of symptomatic imipramine ingestion in our locality. [ncbi.nlm.nih.gov]

  CV: orthostatic hypotension, tachycardia, ECG changes, hypertension, MI, arrhythmias, heart block, precipitation of heart failure. EENT: blurred vision, tinnitus, mydriasis. [glowm.com]

  Cardiac abnormalities may include arrhythmia, tachycardia (fast or irregular heartbeat), ECG evidence of impaired conduction, and signs of congestive failure. [healthyplace.com]

  […] drowsiness, confusion, seizures, headache, anxiety, tremors, stimulation, weakness, insomnia, nightmares, extrapyramidal symptoms in geriatric patients, increased psychiatric symptoms, paresthesia Cardiovascular: orthostatic hypotension, ECG changes, tachycardia [en.wikipedia.org]

• Tinnitus

  A chart review of 475 patients treated with tricyclic antidepressants indicated that tinnitus occurred in about 1% of the patients. The case vignettes of 5 patients who developed tinnitus in the course of imipramine therapy are presented. [ncbi.nlm.nih.gov]

  […] nightmares, extrapyramidal symptoms in geriatric patients, increased psychiatric symptoms, paresthesia Cardiovascular: orthostatic hypotension, ECG changes, tachycardia, hypertension, palpitations, dysrhythmias Eyes, ears, nose and throat: blurred vision, tinnitus [en.wikipedia.org]

  EENT: blurred vision, tinnitus, mydriasis. GI: dry mouth, constipation, nausea, vomiting, anorexia, paralytic ileus, abdominal cramps. GU: urine retention, testicular swelling, impotence. [glowm.com]

  Neurological: Numbness, tingling, paresthesias of extremities; incoordination, ataxia, tremors; peripheral neuropathy; extrapyramidal symptoms; seizures, alterations in EEG patterns; tinnitus. [healthyplace.com]

• Sweating

  I sweat ALOT and VERY easily since I started this as well. Report [everydayhealth.com]

  […] difficulty breathing, dilated pupils, drowsiness, heart failure, high fever, involuntary writhing or jerky movements, irregular or rapid heartbeat, lack of coordination, low blood pressure, overactive reflexes, restlessness, rigid muscles, shock, stupor, sweating [generalhlthnews.org]

  Anticholinergic effects, increased sensitivity to the sun, postural hypotension, weight gain, sleepiness, sweating. Dosages Recommended by Investigators. [anxieties.com]

  Sweating a lot. Flushing. Feeling tired or weak. Headache. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. [drugs.com]

• Pruritus

  […] increased appetite, cramps, epigastric distress, jaundice, hepatitis, stomatitis, constipation, taste change Genitourinary: urinary retention Hematological: agranulocytosis, thrombocytopenia, eosinophilia, leukopenia Skin: rash, urticaria, diaphoresis, pruritus [en.wikipedia.org]

  Skin: diaphoresis, rash, urticaria, photosensitivity, pruritus. Other: gynecomastia, galactorrhea and breast enlargement, altered libido, SIADH, hypersensitivity reaction. [glowm.com]

• Aggressive Behavior

  Gilles de la Tourette's syndrome (GTS) is a chronic neuropsychiatric disorder characterized by multiple involuntary motor and phonic tics associated with behavioural disturbances including obsessive-compulsive and aggressive behavior, depression and, [ncbi.nlm.nih.gov]

  behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. [medlineplus.gov]

• Loss of Libido

  Loss of libido was assessed by both the Hamilton Rating Scale for Depression and the SCL-90. [nature.com]

• Hot Flushes

  The most commonly reported side effects when taking Tofranil tablets 25mg include: weight gain, anorexia, tremor, tachycardia (rapid heart beat), vasodilation (hot flushes), orthostatic hypotension or dizzy spell (low blood pressure when standing up), [inhousepharmacy.vu]

  Anticholinergic side effects: Dry mouth, blurred vision or double vision, constipation, sweating, hot flushes, difficulty urinating or urinary retention, pupil dilation, glaucoma and intestinal paralysis. [medizzine.com]

• Insomnia

  In addition, this child experienced initial insomnia and nocturnal enuresis, problems not previously reported with fragile X. [ncbi.nlm.nih.gov]

  A tricyclic drug, C 19 H 24 N 2, used in the form of its salts to treat depression and enuresis. imipramine Neuropharmacology A dibenzazepine class tricyclic antidepressant used for depression, enuresis Adverse effects Insomnia, numbness, tingling, tremors [medical-dictionary.thefreedictionary.com]

  Physical Symptoms of Depression in Pictures Depression can cause physical problems such as insomnia, chest pain, fatigue, headaches, and more. Learn the signs of depression... [medicinenet.com]

  The most common side effects are headaches, drowsiness, dry mouth, constipation and insomnia. [anxieties.com]

• Paresthesia

  Central nervous system: dizziness, drowsiness, confusion, seizures, headache, anxiety, tremors, stimulation, weakness, insomnia, nightmares, extrapyramidal symptoms in geriatric patients, increased psychiatric symptoms, paresthesia Cardiovascular: orthostatic [en.wikipedia.org]

  Adverse reactions CNS: drowsiness, dizziness, excitation, tremor, confusion, hallucinations, anxiety, ataxia, paresthesia, nervousness, EEG changes, seizures, extrapyramidal reactions, CVA. [glowm.com]

  Neurological: Numbness, tingling, paresthesias of extremities; incoordination, ataxia, tremors; peripheral neuropathy; extrapyramidal symptoms; seizures, alterations in EEG patterns; tinnitus. [healthyplace.com]

• Vertigo

  Nervous side effects: disorientation, vertigo, tiredness, weakness, headache, difficulty concentrating, confusion, agitation, mood changes, aggressiveness, difficulty sleeping, hallucinations, anxiety, restlessness, pricking sensation, tremor, muscle [medizzine.com]

• Torsades De Pointes

  Certain circumstances may increase risk of torsade de pointes and/or sudden death in association with drugs that prolong the QTc interval (eg, bradycardia, hypokalemia or hypomagnesemia, coadministration with other drugs that prolong QTc interval, presence [reference.medscape.com]

• Electrocardiogram Change

  Common side effects of imipramine include dry mouth, drowsiness, dizziness, low blood pressure, rapid heart rate, urinary retention, and electrocardiogram changes. Overdose can result in death. [en.wikipedia.org]

The wide use of imipramine (Tofranil) for the treatment of nocturnal enuresis continues in spite of the unique dangers associated with this drug. [ncbi.nlm.nih.gov]

Despite a good prognosis and the beneficial effect of reassurance for many patients, most continue to have chest pain that may result in visits to the emergency room, admission to the coronary care unit, and even repeat cardiac catheterization 1-5,7-9 [nejm.org]

The rapid resolution of intraventricular conduction delay and normalization of the QRS-T complexes after gastric lavage, installation of activated charcoal and alkalinization of the blood strongly implicates imipramine intoxication in the etiology of [ncbi.nlm.nih.gov]

Within the group of depressions, few etiologic principles have been substantiated and little agreement exists on subgroups. Consequently, differential drug responses are not clearly understood. [pharmrev.aspetjournals.org]

Genitourinary: urinary retention Hematological: agranulocytosis, thrombocytopenia, eosinophilia, leukopenia Skin: rash, urticaria, diaphoresis, pruritus, photosensitivity Imipramine affects numerous neurotransmitter systems known to be involved in the etiology [en.wikipedia.org]

The literature pertaining to etiology, epidemiology, pathophysiology and management of TCA-induced lung injury has been reviewed. In one series of severe TCA overdose, an ARDS rate of 9% was reported. [ncbi.nlm.nih.gov]

Both the clinical features and the pathophysiology of the serotonin syndrome are discussed. [ncbi.nlm.nih.gov]

The pathophysiology of functional dyspepsia is not fully understood and the correlation of those proposed mechanisms with the clinical characteristics and treatment response is poor. [clinicaltrials.gov]

Pathophysiological dilemma of syndrome X. Circulation 1992 ;85: 883 - 892 23. Clouse RE, Lustman PJ. Psychiatric illness and contraction abnormalities of the esophagus. N Engl J Med 1983 ;309: 1337 - 1342 24. [nejm.org]

To try to prevent this complication, early intubation should be considered to avoid aspiration, and cautious volume loading, plus judicious use of alpha-adrenergic agonists, is indicated to prevent protracted hypotension. [ncbi.nlm.nih.gov]

There is not enough information to explain how imipramine prevents bedwetting. Imipramine comes as a tablet and a capsule to take by mouth. [medlineplus.gov]

Imipramine Overview Reviewed: September 18, 2013 Updated: July 21, 2016 Imipramine is a prescription medication used to treat the symptoms of depression and to prevent bedwetting in children. [rxwiki.com]