Prophylactic treatment with danazol, an androgen, has been shown to stimulate the synthesis of C1-INH, but prolonged treatment may result in unpleasant side effects, such as virilization in women and suppression of testosterone production in men. [brainkart.com]

Patients with a defect in formation of the MAC (late complement components) are at high risk for recurrent infection with Neisseria gonorrhoeae or Neisseria meningitidis. [immunopaedia.org.za]

Terminal pathway (C5-C9): The lack of MAC formation results in severe recurrent infection by Neisseria gonorrhoeae or Neisseria meningitidis. C1INH: Primary and secondary deficiency of C1INH leads to uninhibited cleavage of C4 by C1s. [emedicine.medscape.com]