The patient may have other features, best remembered with the SOAPBRAINMD mnemonic: serositis, oral ulcers, arthritis, photosensitivity, blood dyscrasias, renal involvement, ANA positive, immunologic phenomena [anti-dsDNA, antiphospholipid antibodies) [lecturio.com]

In another 25 % of cases, patients present with an acute nephritic syndrome with hypertension, proteinuria, hematuria, and periorbital edema. The variability of the clinical presentation of MPGN mirrors the disease process. [lecturio.com]

edema and later pitting edema Weight gain Possibly frothy urine Hypertension Hypercoagulable state with increased risk of thrombosis and embolic events ; (e.g., pulmonary embolism, renal vein thrombosis ) Increased susceptibility to infection Symptoms [amboss.com]

Imaging tests may also be done if a certain secondary cause of MPGN is suspected, such as a chronic abscess, in which case CT imaging may be useful, or endocarditis, using an echocardiogram for diagnostic confirmation. [lecturio.com]

The patient may have other features, best remembered with the SOAPBRAINMD mnemonic: serositis, oral ulcers, arthritis, photosensitivity, blood dyscrasias, renal involvement, ANA positive, immunologic phenomena [anti-dsDNA, antiphospholipid antibodies) [lecturio.com]

[…] immunofluorescence, aims to capture the pathogenesis behind the MPGN lesion A C3 glomerulopathy is a proliferative glomerulonephritis, usually (but not exclusively) with a MPGN pattern on light microscopy, with C3 staining alone on immunofluorescence, implicating hyperactivity [nature.com]

[…] glomerulopathies, best represented by dense deposit disease and C3 GN. [15] A C3 glomerulopathy is a proliferative GN, usually (but not exclusively) with an MPGN pattern on light microscopy, with C3 staining alone on immunofluorescence, implicating hyperactivity [mjdrdypu.org]

We report a case in which a patient presented with hypertension, seizures, proteinuria, renal impairment and immune complex-mediated MPGN on kidney biopsy. Months later, she presented with classical TMA. [casereports.bmj.com]

Urine microscopy will often show dysmorphic red blood cells (acanthocytes), leukocytes and RBC casts, indicative of glomerulonephritis. 24-hour urinary protein can be measured to quantify the proteinuria or a spot urine protein-to-creatinine ratio. [lecturio.com]