Due to continual pathological signals in liver and lungs, persistent fever, and an M-component in peripheral blood, a new course of four rituximab doses was given, after which the fever settled, the PET scan normalized, and the M-component disappeared [ncbi.nlm.nih.gov]

Adverse reactions: The main adverse reactions affect the gastrointestinal tract (nausea, vomiting, colic, diarrhea) and are dose-dependant with a tendency to improve with time, and the genitourinary system (urinary urgency, polyuria, dysuria, sterile [scielo.br]

In fact, microscopic-hematuria was resolved in only 16 and 42 % of two-assigned groups in STOP-IgAN, respectively. Okabayashi et al. provided a timely message regarding the significance of immunosuppressive treatment of IgAN. [ncbi.nlm.nih.gov]