I present a case of 23 year old female gravida 4 para 3 with recurrent impetigo herpetiformis at 26 weeks gestation. She presented with a one month history of pustular lesions which responded to treatment with prednisone. [ncbi.nlm.nih.gov]

• Fever

  Unlike other pregnancy dermatoses, it can be associated with constitutional symptoms including fever, rigors, arthralgia and complications of secondary infection and sepsis. There is an increased risk of fetal anomalies and stillbirths. [ncbi.nlm.nih.gov]

• Goiter

  Keywords Psoriasis Goiter Hypoparathyroidism Nodular Goiter Calcium Gluconate Case presentation A 38-year-old Egyptian woman was admitted to Cairo University Hospital with extensive exfoliation of her skin. [casesjournal.biomedcentral.com]

• Galactorrhea

  […] distress - Vasa praevia - Uterine rupture - hemorrhage - Placenta accreta - Umbilical cord prolapse - Amniotic fluid embolism Maternal complications in the weeks after childbirth Puerperal fever - Peripartum cardiomyopathy - Postpartum thyroiditis - Galactorrhea [wikidoc.org]

• Palpitations

  General situation worsens and systemic symptoms including lassitude, headache, fever, palpitation, nausea, diarrhea, tetani as well as eruption.(7) In our case, lesions started from pubical zone and expanded to the body. [perinataljournal.com]

• Prolapse

  Placental abruption Complications of labour and delivery Premature birth - Postmature birth - Cephalopelvic disproportion - Dystocia ( Shoulder dystocia ) - Fetal distress - Vasa praevia - Uterine rupture - hemorrhage - Placenta accreta - Umbilical cord prolapse [wikidoc.org]

• Carpopedal Spasm

  Carpopedal spasm may be positive before other manifestations of hypocalcemia. [8] If carpopedal spasm appears, treatment with intravenous Ca ++ is indicated until the signs and symptoms of hypocalcaemia subside without waiting for serum calcium levels [joacc.com]

• Skin Rash

  Several skin rashes that occur during pregnancy are abnormal and potentially harmful to the fetus. Whenever an unusual rash occurs in pregnancy, medical attention should be sought as soon as possible. [livestrong.com]

• Pustular Rash

  At 35 weeks' gestation, the patient developed a severely pruritic pustular rash with fever and leukocytosis. The skin of the affected areas was biopsied and showed intraepidermal pustules with a neutrophilic infiltrate. [ncbi.nlm.nih.gov]

  Henson TH, Tuli M, Bushore D, Talanin NY: Recurrent pustular rash in a pregnant woman. Arch Dermatol 2000;136:1055-1060. Baker H, Ryan TJ: Generalized pustular psoriasis. A clinical and epidemiological study of 104 cases. [karger.com]

  Recurrent pustular rash in a pregnant woman. Arch Dermatol 2000;136: 1055-60. 8. Sauer GC, Geha BJ. Impetigo herpetiformis: report of a case treated with corticosteroid-review of the literature. Arch Dermatol 1961;83: 119-26. 9. Baker H, Ryan TJ. [jsms.sch.ac.kr]

  In addition to the typical pustular rash with associated systemic symptoms, PPP can present with other cutaneous manifestations and variations. [dovepress.com]

• Vaginal Bleeding

  She had no history of per vaginal bleeding or drainage of liquor. On obstetric evaluation, she had a fundal height corresponding with gestational age. Obstetric ultrasound yielded normal findings. The patient was admitted for inpatient management. [panafrican-med-journal.com]

  She had no history of The condition was first reported by Ferdinand Ritter von Hebra in per vaginal bleeding or drainage of liquor. On obstetric evaluation, 1872. [docksci.com]

• Neglect

  Even though the case is not new per se, it reveals the natural course of this rare disease because the condition was neglected and given no oral treatment throughout the entire pregnancy. [ncbi.nlm.nih.gov]

After six weeks of oral prednisolone treatment, the lesions improved, but there were still new pustule formations and narrowband ultraviolet B treatment was added. [ncbi.nlm.nih.gov]

It was previously associated with high maternal and fetal mortality and morbidity, but now has a better prognosis. [ncbi.nlm.nih.gov]

Early diagnosis and proper treatment is important in order to get a better prognosis for both the mother and baby. [e-sciencecentral.org]

This similarity has led authors to name the disease "pustular psoriasis of pregnancy".2 The maternal-fetal prognosis is uneven. [scielo.br]

The etiology of the disease is unclear and it is not known if genetic factors play a role. We present two sisters (twins) with impetigo herpetiformis supporting an inheritance pattern. [ncbi.nlm.nih.gov]

Abstract Impetigo Herpetiformis is a rare pustular dermatosis that typically occurs in pregnant women with unknown etiology. [unboundmedicine.com]

Since the patient had no recurrence while on progesterone-containing contraceptive pills, the suggestion of progesterone's role in the etiology is unlikely. Further case studies and reports could clarify more on the etiology of this rare disease. [the-medical-dictionary.com]

Baker H, Ryan TJ: Generalized pustular psoriasis: a clinical and epidemiological study of 104 cases. Brit J Dermatol 1968;80:77. [karger.com]

A clinical and epidemiological study of 104 cases. Br J Dermatol 80:771–793 PubMed CrossRef Google Scholar 4. Beveridge G W, Harkness RA, Livingstone JR (1966) Impetigo herpetiformis in two successive pregnancies. [link.springer.com]

A better understanding of the pathophysiology of AIKD is likely to lead to innovative, targeted therapies that benefit patients. [kclpure.kcl.ac.uk]

Impetigo herpetiformis is a rare dermatosis of pregnancy that requires early recognition and treatment to prevent maternal and fetal morbidity. Combination therapy using oral corticosteroids and short-term methotrexate is effective. [ncbi.nlm.nih.gov]

Your skin Holds body fluids in, preventing dehydration Keeps harmful microbes out, preventing infections Helps you feel things like heat, cold, and pain Keeps your body temperature even Makes vitamin D when the sun shines on it Anything that irritates [icdlist.com]

Good handwashing prevents spread. ...Read more [healthtap.com]