Blood tests may include the following: Hemoglobin—will be lower than normal if any type of anemia is present Mean corpuscular volume (MCV)—measures the size of the red blood cell and will be larger than normal if folic acid deficiency is present Color [empowher.com]

A higher risk of presenting OW/OB was found for participants with FA intake less than the RDI of 400 µg/day and for those with VB12 intake less than the RDI of 2.4 µg/day. [dspace.lboro.ac.uk]

Assessment of serum copper levels may be beneficial when clinical signs of overload or deficiency are present. [www2.kidney.org]

With a lower UL, the percentage of persons exceeding the UL would be higher than presented in this study. [link.springer.com]

An important unanswered question about folate is whether the present RDA is enough to normalize MTHFR enzyme levels in individuals with the genetic variation. Authored by Dr Peter Engel in 2010, reviewed and revised by Angelika Friedel on 29.06.2017 [nutri-facts.org]

The presentation typically consists of macrocytosis and hypersegmented polymorphonuclear leukocytes (PMNs). [23] More detailed laboratory findings are discussed in the Workup section. [emedicine.medscape.com]

It is important to confirm a diagnosis before treatment begins. Treatment A folic acid supplement is often the first step. It can increase the folic acid in the body. Related conditions may also need treatment. [cancercarewny.com]

It is especially important to confirm a diagnosis of folic acid deficiency before treatment with supplemental folic acid begins. [empowher.com]

The relationship of vitamin C and folic acid has been reported in dermatological literature, most extensively by Montes, a world-renowned expert on the role of vitamins and nutrition in the treatment of vitiligo. [blog.recouleur.com]

Accepted Folic acid deficiency (prophylaxis and treatment)—Folic acid is indicated for prevention and treatment of folic acid deficiency states, including megaloblastic anemia and in anemias of nutritional origin, pregnancy, infancy, or childhood. {01 [drugs.com]

Neural tube defects: Prevalence, etiology and prevention. Int J Urol 2009;16(1):49-57. Bassuk AG, Kibar Z. Genetic basis of neural tube defects. Semin Pediatr Neurol 2009;16(3):101-10. Beaudin AE, Stover PJ. [cps.ca]

Also, a genetic component in NTD etiology is evidenced by the increased risk in women with a family history of an NTD and also by variations in risk among ethnicities (37). [lpi.oregonstate.edu]

Based on this epidemiologic evidence, several randomized controlled trials were initiated investigating the effect of the B vitamins (including folic acid) on cancer risk. [sciencebasedmedicine.org]

Journal of Epidemiology and Community Health, Vol. 69, Issue. 9, p. 826. CrossRef Google Scholar Ramage, Stephanie McCargar, Linda Berglund, Casey Harber, Vicki Bell, Rhonda and Team, the 2015. [cambridge.org]

Cancer Epidemiology Biomarkers & Prevention 16(7): 1325–1329. [els.net]

Epidemiologic and genetic aspects of spina bifida and other neural tube defects. Dev Disabil Res Rev 2010;16(1):6-15. Blencowe H, Cousens S, Modell B, Lawn J. Folic acid to reduce neonatal mortality from neural tube disorders. [cps.ca]

[…] supplementation and child Asperger syndrome or pervasive developmental disorder-not otherwise specified. [6] Effects on carcinogens Diminished folate status has historically been associated with enhanced carcinogenesis. [16] As recently as 2002, authors cited epidemiologic [emedicine.medscape.com]

Understanding Pathophysiology (3rd ed.). Mosby. p. 543. ISBN 978-0-323-02368-9. ^ Tamparo C (2011). Diseases of the Human Body (Fifth ed.). Philadelphia, PA. p. 337. ISBN 978-0-8036-2505-1. ^ Haslam N, Probert CS (February 1998). [en.wikipedia.org]

Prevention for Other High-Risk Persons. No intervention or observational studies address prevention for other high-risk persons. [pediatrics.aappublications.org]

Cancer Epidemiology Biomarkers & Prevention 16(7): 1325–1329. [els.net]

“Updated Estimates of Neural Tube Defects Prevented by Mandatory Folic Acid Fortification — United States, 1995–2011.” Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 16, Jan 2015. Web. [blog.insidetracker.com]

A further study suggests that an extra 200 mg/day or possibly 100 µg/day if taken habitually in fortified food would prevent most if not all of folate-preventable NTDs ( 26 ). [fao.org]

Proper nutrition prior to conception and during pregnancy can help prevent birth defects. Learn about the different nutrients to include in your diet. [everydayhealth.com]