Presentation
Materials And Methods : We performed a retrospective review of head sonography of infants (admitted between November 1, 2014, and March 31, 2015) who presented with encephalopathy. [pubfacts.com]
We noticed 3 patterns: 1- to 2-month-old infants (16/41) presented with lactic acidosis. Infants older than 5 months of age (11/41) presented with Wernicke encephalopathy. [ajnr.org]
Most of the patients presented with severe respiratory irregularities. [academic.oup.com]
"Early Vitamin History," presented in a humorous way, is his most favorite topic. [books.google.it]
Entire Body System
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Pediatric Disease
Succinct, targeted coverage of normal childhood growth and development, as well as the diagnosis, management, and prevention of common pediatric diseases and disorders, make this an ideal medical reference book for students, pediatric residents, nurse [books.google.ro]
Respiratoric
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Sighing
Common clinical manifestations included altered sensorium, external ophthalmoplegia, seizures, hypotonia, characteristic irregular sighing or sobbing respiration along with a history of fever and vomiting ( Table 1 ). [academic.oup.com]
On the other hand, sit all day in a moping posture, sigh, and reply to everything with a dismal voice, and your melancholy lingers. [books.google.it]
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Respiratory Abnormalities
Within 24 h the first signs of improvement were noted in the level of consciousness, respiratory abnormalities and ptosis whereas head control, tone, involuntary movements and milestones recovered partially over next few weeks. [academic.oup.com]
Cardiovascular
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Tachycardia
The clinical features are: anorexia oedema tachycardia tachypnoea There is a fatal outcome unless treatment is initiated rapidly. Links: treatment of infantile beriberi beriberi [gpnotebook.co.uk]
Abstract An infant, 5½ months of age, died after a brief acute illness characterized by irritability and somnolence leading terminally to coma, and by excessive sweating, abdominal distension, tachypnea and tachycardia. [pediatrics.aappublications.org]
Neurologic
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Delayed Milestone
In patients with developmental delay, milestones and tone were slow to recover during 4–14 weeks. Normal breastfeeding was achieved in a mean of 6 hours. The mean duration of the hospital stay was 3.25 days. [ajnr.org]
All 15 patients who were re-examined within 3–6 months of initial illness, were clinically normal except two who still had hypotonia, delayed milestones and persistence of brain lesions on imaging. [academic.oup.com]
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Dystonia
Klinische Padiatrie 201(2): 86-92, 1989 Dystonia as a presenting sign of subacute necrotizing encephalomyelopathy in infancy. European Journal of Pediatrics 144(6): 589-591, 1986 Subacute necrotizing encephalomyelopathy. [eurekamag.com]
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Grunting
Additional admission information was collected for infants with clinical beriberi-these infants had lethargy (74%), poor feeding (72%), vomiting (60%), dyspnoea (81%), grunting (82%, n 45), palpable liver (96%, n 27), peripheral oedema (25%, n 44 [journals.plos.org]
Workup
EEG
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Hypsarrhythmia
Journal of the Medical Association of Thailand 70(10): 596-603, 1987 Leigh's subacute necrotizing encephalomyelopathy in a child with infantile spasms and hypsarrhythmia. [eurekamag.com]
Small numbers of virus enter the blood and go to other sites where the virus multiplies more […] Infantile spasms A seizure disorder of infancy and early childhood with the onset predominantly in the first year of life of myoclonic seizures, hypsarrhythmia [definithing.com]
Treatment
The clinical features are: anorexia oedema tachycardia tachypnoea There is a fatal outcome unless treatment is initiated rapidly. Links: treatment of infantile beriberi beriberi [gpnotebook.co.uk]
Unapparent vitamin B1 deficiency may complicate the illness of infants presenting with other diseases and supplementary treatment with vitamin B1 could potentially improve their outcome and reduce infant mortality. [apamedcentral.org]
Expand your knowledge concerning rare and neglected tropical diseases, as well as how diagnosis and treatment takes place in resource-poor settings. [books.google.it]
Prognosis
Although, untreated Beriberi can eventually lead to death Commencing thiamine supplementation can cause an improvement in the symptoms If congestive heart failure occurs, the prognosis is poor. [dovemed.com]
Prognosis The prognosis for beriberi is usually good, unless patients have established Korsakoff syndrome. When patients have progressed to this stage, the degree of damage is only minimally reversible. [namrata.co]
Prognosis of Beriberi The prognosis for beriberi is usually good, unless patients have established Korsakoff syndrome. When patients have progressed to this stage, the degree of damage is only minimally reversible. 39Biochemistry for medics 40. [slideshare.net]
Prognosis Mortality is rare and is usually associated with the wet form due to cardiac failure. [ 26 ] Morbidity is also rare and usually presents in the dry form with neurological symptoms. [patient.info]
Etiology
"The cure of infantile beriberi by the administration to the infant of an extract of rice polishing, and the bearing thereof on the etiology of beriberi" Bull Manila Med Soc 6(2): 26-29, 1912 14. [herdin.ph]
The cure of infantile beriberi by the administration to the infant of an extract of rice polishing, and the bearing thereof on the etiology of beriberi. Bull Manila Med Soc 1912;6:26-33. Disclosure: Dr. [n.neurology.org]
The etiology of " moist beri-beri" has not yet been fully investigated, but there seems to be some suggestion that a relationship exists between this malady and the poor quality of the milk yielded by Filipino mothers. [kundoc.com]
vitamin B 12 deficiency in patients with diseases affecting the terminal ileum ) Etiology Maldigestion Impaired breakdown of food in the intestinal lumen Exocrine pancreatic insufficiency ; lack of enzymes reduced hydrolysis of carbohydrates, proteins [amboss.com]
Epidemiology
Although this is almost the exact epidemiology of modern SIDS, this well researched truth is ignored. [hormonesmatter.com]
[…] concurrently, including Wernicke's encephalopathy (mainly affecting the central nervous system), Korsakoff's syndrome (amnesia with additional psychiatric manifestations), and Wernicke-Korsakoff syndrome (with both neurologic and psychiatric symptoms) Epidemiology [flipper.diff.org]
In the early 20 th century there was an enormous international effort to understand the causes, epidemiology and prevention of this devastating and common disease in the rice consuming societies of Asia [1] – [9]. [journals.plos.org]
Detailed epidemiologic, dietary, clinical, laboratory, and treatment data of these children had been obtained. [ajnr.org]
Another translation is 'I cannot, I cannot'. [ 2 ] Epidemiology Beriberi was endemic in some areas of the world and may be related to the consumption of milled rice. [patient.info]
Pathophysiology
Pathophysiology Thiamine in the human body has a half-life of 18 days and is quickly exhausted, particularly when metabolic demands exceed intake. [flipper.diff.org]
The pathophysiology of cardiac dysfunction in infantile beriberi is not understood and, as far as we are aware, there have been no echocardiographic or cathertisation studies. [journals.plos.org]
This type of rice has its husk removed in order to extend its lifespan, but also has the unintended side-effect of removing the primary source of thiamine. [1] Pathophysiology Edit Thiamine has a half-life of 18 days and is quickly exhausted, particularly [psychology.wikia.com]
Pathophysiology of Thiamine deficiency (Beri-Beri) Deficiency causes degeneration of peripheral nerves, thalamus, mammillary bodies, and cerebellum. Cerebral blood flow is markedly reduced, and vascular resistance is increased. [namrata.co]
The data provide important insights on the nutritional pathophysiology of thiamine depletion, repletion, and therapeutics and a sobering reminder that nutritional deficiency disease, including beriberi, persists as an important cause of morbidity and [ajcn.nutrition.org]
Prevention
“Through fortification (adding vitamins to foods eaten every day) we can prevent beriberi without asking [Cambonian women] to change a thing. [lfs-lc-collabtm.sites.olt.ubc.ca]
Rickets was common in northern cities and was more rampant in industrial cities as industrial pollution prevented children from sunlight exposure. [books.google.it]
Thiamine deficiency and its prevention and control in major emergencies. WHO/NHD/99.13. pages 9 and 47. [meducator3.net]