Presentation
The aims of this review are to present recent research investigating the connection between infantile colic and migraine. [ncbi.nlm.nih.gov]
Entire Body System
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Irritable Infant
Rabbitt, Irritable Infant, Nelson Pediatric Symptom-Based Diagnosis, 10.1016/B978-0-323-39956-2.00026-1, (411-420.e2), (2018). [doi.org]
Do not discharge an irritable infant if "extreme fussiness" has not resolved, particularly if a "red flag" is present. Questions 1. Which of these are NOT a feature of the infant colic syndrome?. [hawaii.edu]
Double-blind placebo-controlled trial of omeprazole in irritable infants with gastroesophageal reflux. J Pediatr. 2003;143(2):219–223. 27. Iacovou M, Ralston RA, Muir J, et al. Dietary management of infantile colic: a systematic review. [web.archive.org]
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Edema of the Finger
[…] of toes, fingers, or penis; hair found curled up near infant Hair wrapped around finger, toe, or penis None Inadequate bottle feeding Aggressive feeding Clinical dehydration, loss of fat from cheeks, weight loss or poor weight gain Weight increase with [web.archive.org]
Gastrointestinal
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Colic
At this stage, the probiotic cannot be recommended for treating infantile colic in formula-fed infants, nor can it be routinely used to prevent infantile colic. [ncbi.nlm.nih.gov]
Family life 1 year after infantile colic. Arch Pediatr Adolesc Med. 1996;150:1032–6. 13. Reust CE, Blake RL Jr. Diagnostic workup before diagnosing colic. Arch Fam Med. 2000;9:282–3. 14. Weissbluth M. Colic. In: Burg FD, Gellis SS, Kagan BM. [web.archive.org]
Infantile colic, prolonged crying and maternal postnatal depression. Acta Paediatrica, 98, 1344–1348. PubMed CrossRef Google Scholar 11. Barr, R. G. (2002). Changing our understanding of infant colic. [dx.doi.org]
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Abdominal Pain
The population studied was matched with healthy control without history of recurrent abdominal pain, enrolled among pediatricians practicing primary health care. [ncbi.nlm.nih.gov]
Symptoms: Paroxysms (sudden attacks) of crying Apparent abdominal pain Irritability Suggestions: Some doctors believe that colic exists in order to change deeply ingrained relationship habits. Colic demands attention. [himalayawellness.com]
[…] in·fan·tile col·ic episodes of abdominal pain due to abnormal muscular contraction of the intestine in infants. infantile colic Etymology: L, infans, unable to speak; Gk, kolikos, pain in the colon a descriptive term for a suggested intestinal cause of [medical-dictionary.thefreedictionary.com]
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Nausea
[…] abdominal tenderness R10.825 Periumbilic rebound abdominal tenderness R10.826 Epigastric rebound abdominal tenderness R10.827 Generalized rebound abdominal tenderness R10.83 Colic R10.84 Generalized abdominal pain R10.9 Unspecified abdominal pain R11 Nausea [icd10data.com]
Rhinoconjunctivitis Bronchial asthma T cell-mediated (with or without involvement of IgE) Delayed type reaction 24 hours after food ingestion In infants and adults Baker’s asthma in adults Gastrointestinal tract Colitis Diarrhea Gastroenteritis Anorexia Nausea [ncbi.nlm.nih.gov]
Fang Ruida more than once stressed that his ideas, theories and doctrines from all over the world, rather than his personal nausea. [flickr.com]
Liver, Gall & Pancreas
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Hepatosplenomegaly
Red Flags in the Evaluation of the Crying Infant Finding Possible cause Distended abdomen Abdominal mass, hepatosplenomegaly, Hirschsprung disease, intestinal malrotation with volvulus, necrotizing enterocolitis Fever Acute otitis media, appendicitis, [web.archive.org]
Neurologic
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Hyperalgesia
[…] the available data fail to provide insight into the exact triggers of infantile colic, these do allow for the hypothesis that certain infants are predisposed to dietary protein intolerance and disturbed gut motility, such as visceral hypersensitivity/ hyperalgesia [ncbi.nlm.nih.gov]
Alternatively, strategies to improve gut microflora and reduce hyperperistalsis and hyperalgesia may be more appropriate. These will be considered in turn below. [jfhc.co.uk]
Neonatal gastric suctioning results in chronic visceral and somatic hyperalgesia: role of corticotropin releasing factor. Neurogastroenterol Motil. 2007;19(8):692-699. PubMed Google Scholar Crossref 16. Lin HC. [doi.org]
Electro-acupuncture relieves chronic visceral hyperalgesia in rats. Neurosci. Lett. 376, 20–23 (2005). 258. Liao, J. M. et al. Electroacupuncture at Hoku elicits dual effect on autonomic nervous system in anesthetized rats. Neurosci. [nature.com]
Workup
[…] may be worthwhile; positive results may indicate an underlying GI problem Stool may be tested for occult blood to rule out cow’s milk allergy Irritability and crying may be associated with GERD because of the pain associated with esophagitis See Workup [emedicine.com]
However, the presence of fever may necessitate a workup for sepsis and involve blood and urine cultures, imaging and even lumbar puncture. [statpearls.com]
Diagnostic workup before diagnosing colic. Arch Fam Med. 2000;9:282–3. 14. Weissbluth M. Colic. In: Burg FD, Gellis SS, Kagan BM. Gellis & Kagan’s Current pediatric therapy. 16th ed. Philadelphia: Saunders, 1999:674–8. 15. Levitzky S, Cooper R. [web.archive.org]
Treatment
Primary end-points were crying time at mid-treatment, at the end of treatment and at a 1-month follow-up. A 30-min mean difference (MD) in crying time between acupuncture and control was predefined as a clinically important difference. [ncbi.nlm.nih.gov]
Neither concomitant treatments nor side effects were reported. [doi.org]
Prognosis
Prognosis The prognosis is excellent. Most infants with colic recover spontaneously by 3-4 months of age. [patient.info]
This app have lot of information of symptoms, Diagnosis, Prognosis, Treatment & etc. Note: All information about the application is for educational purposes only. For specific advice, diagnoses, and medical care, consult your doctor. [play.google.com]
Causes Unknown[1] Diagnostic method Based on symptoms after ruling out other possible causes[1] Differential diagnosis Corneal abrasion, hair tourniquet, hernia, testicular torsion[2] Treatment Conservative treatment, extra support for the parents[1][3] Prognosis [en.wikipedia.org]
The prognosis is good for the majority who suffer with transient problems over the first 2 years of life. References 1. Clinical Knowledge Summaries (CKS). Colic- infantile [online]. 2011. Available at: [Accessed March 2013] 2. [jfhc.co.uk]
Etiology
The etiology of infantile colic has yet to be definitively elucidated, but there is increasing research to support its relationship to migraine. [ncbi.nlm.nih.gov]
The etiology of infantile colic remains unclear. Many risk factors assessed but no one is certain. We invastigate ethiology, risk factors and treatment methods of infantile colic. Key words: Infantile colic, ethiology, treatment [scopemed.org]
Results: At present, infantile colic is an area of clinical research both in terms of etiology and treatment. Various etiological theories have been proposed but none of them are strong enough to completely describe the condition. [indianpediatrics.net]
The term is derived from “kolikos”,the Greek word for colon Various etiologies have been proposed, with gastrointestinal etiologies being a leading thought Classic definitions of colic: Wessel criteria : episodes of crying 3 hours/day, 3 days/week, for [nuemblog.com]
Epidemiology
REVIEW ARTICLE Corresponding Author E-mail address: [email protected] Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.), Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic College [doi.org]
Celiac disease and non-celiac gluten sensitivity Clinical Review State of the Art Review BMJ 2015 ; 351 doi: (Published 05 October 2015) Cite this as: BMJ 2015;351:h4347 Benjamin Lebwohl, assistant professor of medicine and epidemiology 1 2, Jonas F Ludvigsson [dx.doi.org]
At that time little evidence regarding epidemiology, pathophysiology, diagnostic work-up, treatment strategies and follow-up was available. Consequently the criteria for the clinical entities were more experience than evidence based. [ncbi.nlm.nih.gov]
Epidemiology Baby colic is very common, occurring in round 10-30% of infants[1]. It affects males and females equally. Breast-fed and formula-fed infants are equally affected. [patient.info]
Pathophysiology
However, the pathophysiological clues indicate that infantile colic is a shared pathology between the mother and the baby, especially in the case of breastfeeding mothers. [ncbi.nlm.nih.gov]
Pathophysiology has been described in various ways in different studies and yet not conclusive. [banglajol.info]
The pathophysiology of this clinical phenotype is poorly understood, but it is a cause of increasing interest in gluten-free diets in the general population. [dx.doi.org]
Laboratory of Experimental Pathophysiology IRCCS Bari Italy [link.springer.com]
Prevention
Meanwhile, L. reuteri DSM 17938 has been suggested, for the first time, to be possibly effective in preventing infantile colic. [ncbi.nlm.nih.gov]
Shel SC Banks, Megan R Thomas, Morris Gordon, Chris Wallace and Anthony K Akobeng, Probiotics to prevent infantile colic, Cochrane Database of Systematic Reviews, (2016). [doi.org]