Laboratory evidence of influenza A(H1N1) virus infection was present. Two children died as a result of their illness. The association of virus and gastrointestinal haemorrhage is explored. [ncbi.nlm.nih.gov]

The age distribution seen in the present study is compatible with the results of these serological studies. [doi.org]

• Fever

  Fever (frequency, 90.0%), cough (frequency, 74.1%), and rhinorrhea (frequency, 61.8%) were the most frequent symptoms. The mean duration of fever was 2.88 days (standard deviation, 1.66 days). [ncbi.nlm.nih.gov]

  The flu is often characterized by running a high fever--typically 102 degrees or higher, says the AAFP. That fever is generally accompanied by sweating and the chills, and aches and pains all over the body. [livestrong.com]

• High Fever

  A 26-year-old man was admitted to our hospital because of high fever, drowsiness, memory disturbance, and disorientation due to H1N1 influenza virus-associated encephalitis/encephalopathy. [ncbi.nlm.nih.gov]

• Inflammation

  Agency, Gimcheon, Gyeongsangbukdo, 39660, Republic of Korea. 5 Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA. [ncbi.nlm.nih.gov]

• Fatigue

  Infected individuals usually experience a rapid onset of flu symptoms which typically include: muscle aches, high fever, head ache, chills, fatigue, dry cough and runny/stuffy nose. [3dscience.com]

  Orthomyxoviridae USMLE® Step 1 style questions 1 questions Orthomyxoviridae USMLE® Step 2 style questions 1 questions Preview A 10-year-old girl comes to her general practitioner because of fever, shortness of breath, cough, fatigue, muscle aches, and [osmosis.org]

  I think that I don't really have to list the symptoms most people get from the flu since you've almost certainly had it yourself, but just in case you somehow lucked out, the flu typically causes a fever, muscle aches, fatigue, coughing, sneezing, congestion [study.com]

  Six of seven cases of influenza-like illness were mild, with patients reporting subjective (unrecorded) fever ( n = 7), cough ( n = 4), runny nose ( n = 3), headache ( n = 3), muscle pain ( n = 3), sore throat ( n = 2), and fatigue ( n = 1). [doi.org]

• Malaise

  Incidentally, he was found to have some non-specific symptoms, including malaise and myalgias. These findings were attributed to killed-virus H1N1 vaccine given 48 hours earlier. [ncbi.nlm.nih.gov]

  Clinical manifestations (cough, fever, and malaise) are typically mild, but infants are susceptible to serious lower respiratory tract infections [3]. [doi.org]

• Pneumonia

  The purpose of this study was to perform clinicopathological evaluations of patients with pure influenza A virus pneumonia. We performed clinicopathological analyses of four cases of pure influenza A virus pneumonia. [ncbi.nlm.nih.gov]

• Cough

  Yet differing symptoms of the cold are: sore throat; productive, phlegmy coughs; and sneezing. [3dscience.com]

  The illness was acute, with rapid onset, high fever, nonproductive cough, dyspnea, cyanosis, crepitations and rales over both lung bases, and associated arterial hypoxemia, leukopenia, and thrombocytopenia. [ncbi.nlm.nih.gov]

• Respiratory Distress

  These 3 children shared common clinical and radiologic features: rapid and progressive respiratory distress with whole lung atelectasis on chest radiograph. [ncbi.nlm.nih.gov]

• Common Cold

  More severe than the common cold, flu symptoms can cause serious complications like pneumonia and other infections in some people -- especially those with a weakened immune system, including the elderly, the very young and pregnant women. [livestrong.com]

  Cold doesn't affect the "common cold" in study of rhinovirus infections. Douglas RC Jr, Couch RB, Lindgren KM. JAMA. 1967 Feb 13;199(7):29-30. 9. Douglas RG.Jr, Lindgren KM, Couché RB. Exposure to cold environment and rhinovirus common cold. [passeportsante.net]

  The common cold (acute viral nasopharyngitis) is not caused by the Influenza virus, but it is often confused with the flu because it does share similar symptoms such as: fatigue, cough, head ache and runny nose. [3dscience.com]

  Vol 1 4th ed Philadelphia Lippincott Williams & Wilkins (pg. 1533 - 79 ) 28 Production of common colds in human volunteers by influenza C virus, Br Med J, 1968, vol. 4 (pg. 153 - 4 ) Potential conflicts of interest: none reported The nucleotide sequences [doi.org]

• Dyspnea

  The illness was acute, with rapid onset, high fever, nonproductive cough, dyspnea, cyanosis, crepitations and rales over both lung bases, and associated arterial hypoxemia, leukopenia, and thrombocytopenia. [ncbi.nlm.nih.gov]

  Of these 5 children, 4 were hospitalized, and 1 of these 4, a prematurely born 1-year-old boy, had dyspnea due to croup and was receiving oxygen therapy without ventilatory assistance We found cases of multiple infection within 4 families, which suggested [doi.org]

• Severe Clinical Course

  The pathologic change induced by the direct viral invasion cannot be responsible for all of the symptoms, especially for the rapid and severe clinical course of the disease within 24-48 h after the initial respiratory symptoms. [ncbi.nlm.nih.gov]

• Headache

  A headache may also commonly occur along with these symptoms. The flu virus may also cause gastrointestinal symptoms, like vomiting, nausea or diarrhea. [livestrong.com]

  Orthomyxoviridae USMLE® Step 1 style questions 1 questions Orthomyxoviridae USMLE® Step 2 style questions 1 questions Preview A 10-year-old girl comes to her general practitioner because of fever, shortness of breath, cough, fatigue, muscle aches, and headache [osmosis.org]

  The affected person may also have headache, fever, and abdominal cramps (“stomach ache”). [sfcdcp.org]

  On April 4, the veterinarian suffered from high fever and severe headache. [doi.org]

• Pericardial Effusion

  Abstract We report, to our knowledge, the first successful treatment of novel Influenza A (H1N1)/2009 chronic pericardial effusion in an adult. [ncbi.nlm.nih.gov]

• Pseudomonas

  Description of the case of an 8-year-old boy with cystic fibrosis and Pseudomonas aeruginosa infection in whom an oseltamivir-resistant pandemic A/H1N1 influenza virus was demonstrated. [ncbi.nlm.nih.gov]

  Božena Kubíčková, Jana Hadrabová, Lucie Vašková, Václav Mandys, Marie Stiborová and Petr Hodek, Susceptibility of airways to Pseudomonas aeruginosa infection: mouse neuraminidase model, Monatshefte für Chemie - Chemical Monthly, 148, 11, (1993), (2017 [doi.org]

• Streptococcus Pneumoniae

  Topics addressed include the bacteriological, virological and immunological mechanisms impacting invasion upon superinfection on top of underlying influenza virus infection by GAS and other bacteria (i.e., Streptococcus pneumoniae and Staphylococcus aureus [ncbi.nlm.nih.gov]

  McCullers JA, Bartmess KC (2003) Role of neuraminidase in lethal synergism between influenza virus and Streptococcus pneumoniae. J Infect Dis 187(6):1000–1009. https://doi.org/10.1086/368163 PubMed CrossRef Google Scholar 19. [doi.org]

Abstract We report, to our knowledge, the first successful treatment of novel Influenza A (H1N1)/2009 chronic pericardial effusion in an adult. [ncbi.nlm.nih.gov]

Focal reversible encephalopathy has rarely been reported in association with influenza virus infection, although it often provokes diffuse encephalopathies, with a poor prognosis. [ncbi.nlm.nih.gov]

Li Deng, Peng Pang, Ke Zheng, Jiao Nie, Huachong Xu, Sizhi Wu, Jia Chen and Xiaoyin Chen, Forsythoside A Controls Influenza A Virus Infection and Improves the Prognosis by Inhibiting Virus Replication in Mice, Molecules, 10.3390/molecules21050524, 21, [doi.org]

The H1N1 influenza virus is an etiological agent associated with acute myocarditis, but there are few reported cases of fulminant myocarditis caused by the H1N1 virus. [ncbi.nlm.nih.gov]

Petersburg, Russia. 7 Pasteur Institute of Epidemiology and Microbiology, 14 Mira str, 197101, St. Petersburg, Russia. [email protected]. 8 School of Pharmacy, University of Nottingham, Malaysia Campus, 43500, Semenyih, Malaysia. [ncbi.nlm.nih.gov]

To establish a treatment strategy for acute encephalopathy and encephalitis associated with influenza virus infection, the pathophysiology of the disease was investigated through manifestations and laboratory findings of patients. [ncbi.nlm.nih.gov]

Minodier L, Charrel RN, Ceccaldi PE, van der Werf S, Blanchon T, Hanslik T, Falchi A (2015) Prevalence of gastrointestinal symptoms in patients with influenza, clinical significance, and pathophysiology of human influenza viruses in faecal samples: what [doi.org]

Author information 1 Changsha Center for Disease Control and Prevention, Changsha, Hunan, 410001, China. 2 Hunan Provincial Center for Disease Control and Prevention, Changsha, Hunan, China. 3 Changsha Center for Disease Control and Prevention, Changsha [ncbi.nlm.nih.gov]