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Intermittent Explosive Disorder


Presentation

Turkish
  • ) Coskun F...Akca OF 2018 8 Cognitive-behavioral group therapy for intermittent explosive disorder: description and preliminary analysis. ( 29590263 ) Costa AM...Seger L 2018 9 Prevalence and clinical correlates of intermittent explosive disorder in Turkish[malacards.org]
Impulsivity
  • Potenza Show Summary Details Abstract and Keywords Intermittent explosive disorder (IED) is characterized by recurrent episodes of impulsive, uncontrollable aggression out of proportion to the severity of provoking agents.[oxfordhandbooks.com]
  • Explosive Disorder and Aggression. ( 29560894 ) Coccaro EF...Phan KL 2016 32 Self-harm behavior among individuals with intermittent explosive disorder and personality disorders. ( 25300440 ) Jenkins AL...Coccaro EF 2015 33 Emotional intelligence and impulsive[malacards.org]
  • More specifically, studies that were conducted on twins shows that impulsive aggression possesses a powerful genetic influence.[crestwynbehavioral.com]
Anger
  • However, only a minority of people with IED obtain treatment for their uncontrollable anger.[oxfordhandbooks.com]
  • Alvarez-Alonso MJ...Jurado-Barba R 2016 25 White Matter Integrity Reductions in Intermittent Explosive Disorder. ( 27206265 ) Lee R...Coccaro EF 2016 26 Substance use disorders: Relationship with intermittent explosive disorder and with aggression, anger[malacards.org]
  • Intermittent explosive disorder (sometimes abbreviated as IED ) is a behavioral disorder characterized by explosive outbursts of anger and violence, often to the point of rage, that are disproportionate to the situation at hand (e.g., impulsive screaming[en.wikipedia.org]
  • Physical aggression towards animals and/or other individuals Unprovoked violent outbursts that may or may not result in physical harm or injury Frequent verbal arguments and fights Cognitive symptoms: Lack of impulse control Psychosocial symptoms: Rage Anger[crestwynbehavioral.com]
Anxiety Disorder
  • 2 Aggression directed towards others vs. aggression directed towards the self: clinical differences between intermittent explosive disorder and nonsuicidal self-injury. ( 30843959 ) Medeiros GC...Tavares H 2019 3 The co-occurrence and correlates of anxiety[malacards.org]
  • Individuals with IED are, on average, four times more likely to develop depressive or anxiety disorders, and three times more likely to develop substance use disorders. [9] Bipolar disorder has been linked to increased agitation and aggressive behavior[en.wikipedia.org]
  • Some examples of these disorders can include: Antisocial personality disorder Borderline personality disorder Anxiety disorders Substance use disorders Oppositional defiant disorder (ODD) Depressive disorders Attention-deficit/hyperactivity disorder ([crestwynbehavioral.com]
Compulsive Disorder
  • Disorder, Intermittent Explosive Disorder and Sexual Paraphilias. ( 25035563 ) Hebbar S 2014 40 Validity of the new A1 and A2 criteria for DSM-5 intermittent explosive disorder. ( 24321204 ) Coccaro EF...McCloskey MS 2014 41 Elevated plasma inflammatory[malacards.org]
  • Fluvoxamine in the Treatment of Obsessive-Compulsive Disorder and Related Conditions. J Clin Psychiatry, 58(suppl 5), 32-49. a b c Boyd, Mary Ann (2008). Psychiatric nursing: contemporary practice.[en.wikipedia.org]
Suggestibility
  • A suggested explanation for IED is a polymorphism of the gene for tryptophan hydroxylase, which produces a serotonin precursor ; this genotype is found more commonly in individuals with impulsive behavior. [4] IED may also be associated with lesions in[en.wikipedia.org]
Agitation
  • Individuals with IED are, on average, four times more likely to develop depressive or anxiety disorders, and three times more likely to develop substance use disorders. [9] Bipolar disorder has been linked to increased agitation and aggressive behavior[en.wikipedia.org]
Screaming
  • ., impulsive screaming triggered by relatively inconsequential events). Impulsive aggression is not premeditated, and is defined by a disproportionate reaction to any provocation, real or perceived.[en.wikipedia.org]
Excitement
  • This construct was characterized by a "persistent reaction to frustration are "generally excitable, aggressive, and over-responsive to environmental pressures" with "gross outbursts of rage or of verbal or physical aggressiveness different from their[en.wikipedia.org]

Workup

Toxoplasma Gondii
  • Coccaro EF, Lee R, Groer MW, Can A, Coussons-Read M, Postolache TT (March 2016). " Toxoplasma gondii Infection: Relationship With Aggression in Psychiatric Subjects" Archived 2016-03-24 at the Wayback Machine. J Clin Psychiatry 77 (3): 334–341.[en.wikipedia.org]

Treatment

  • However, only a minority of people with IED obtain treatment for their uncontrollable anger.[oxfordhandbooks.com]
  • Medeiros GC...Tavares H 2019 3 The co-occurrence and correlates of anxiety disorders among adolescents with intermittent explosive disorder. ( 30040122 ) Galbraith T...Heimberg RG 2018 4 A wait-list controlled study of a trauma-focused cognitive behavioral treatment[malacards.org]
  • ., motivated by tangible rewards), whereas IED is more of an impulsive, unpremeditated reaction to situational stress. [11] Treatment [ edit ] Treatment is attempted through both cognitive behavioral therapy and psychotropic medication regimens, though[en.wikipedia.org]
  • Thankfully, there are treatment options available that can help individuals learn how to control their impulses, implement appropriate and healthy responses to stressors, and overcome their symptoms from IED.[crestwynbehavioral.com]

Epidemiology

  • The Phenomenology and Epidemiology of Intermittent Explosive Disorder Edited by Jon E. Grant and Marc N.[oxfordhandbooks.com]
  • Epidemiology of psychiatric and alcohol disorders in Ukraine: Findings from the Ukraine World Mental Health survey. Soc Psychiatry Psychiatr Epidemiol 40:681–690, 2005. Coccaro EF, Posternak MA, Zimmerman M (October 2005).[en.wikipedia.org]
  • Intermittent Explosive Disorder. ( 27206265 ) Lee R...Coccaro EF 2016 26 Substance use disorders: Relationship with intermittent explosive disorder and with aggression, anger, and impulsivity. ( 27442963 ) Coccaro EF...Lee R 2016 27 The cross-national epidemiology[malacards.org]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology [ edit ] Impulsive behavior, and especially impulsive violence predisposition has been correlated to a low brain serotonin turnover rate, indicated by a low concentration of 5-hydroxyindoleacetic acid (5-HIAA) in the cerebrospinal fluid[en.wikipedia.org]

Prevention

  • This combination of features makes IED an ideal target for early detection and intervention aimed at secondary prevention of anger attacks as well as primary prevention of secondary disorders.[oxfordhandbooks.com]
  • The final sessions focus on resisting aggressive impulses and other preventative measures. [12] Tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRIs, including fluoxetine, fluvoxamine, and sertraline ) appear to alleviate some[en.wikipedia.org]

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