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Intermittent Hydrarthrosis


Presentation

  • A 49-year-old female presented with intermittent hydrarthrosis affecting the right knee. Numerous calcium pyrophosphate crystals were demonstrated in synovial fluid aspirated from the knee.[ncbi.nlm.nih.gov]
  • Dictionary;2005, p1018 A definition of the medical term "hydrarthrosis" is presented, which means joint effusion.[connection.ebscohost.com]
  • It usually begins in adolescence but can present up to the fifth decade [ 1 , 2 ]. Our two cases are remarkable because both began later than the normally expected age.[academic.oup.com]
  • On the basis that IH is periodic in its presentation, early researchers proposed links with malaria where symptoms are also cyclical, even though the two have different duration cycles.[en.wikipedia.org]
  • This reference guide will be the must-have of any internist or medical professional, as it takes a vast quantity of data across a sweeping grid of disorders, diseases, and presentations, and boils them down to individual parts, facilely indexed, and located[books.google.de]
Arthritis
  • The symptomatic state was associated with existing disease such as rheumatoid arthritis, ankylosing spondylitis, other arthritis, or infection e.g. Brucellosis.[en.wikipedia.org]
  • OTHER TYPES OF ARTHRITIS AND ARTHRITIC SYNDROMES. // Annals of Internal Medicine;May62 Part 2, Vol. 56 Issue 5, p89 Enumerates several types of arthritis and arthritic syndromes.[connection.ebscohost.com]
  • For arthritis, injuries, or other diseases, you may need joint replacement surgery to remove the damaged joint and put in a new one.[icdlist.com]
  • These effusions occur periodically, with recurrent self-remitting episodes of acute arthritis often monthly at or around the menses. Pathophysiology The pathogenesis of Intermittent hydrarthrosis is unknown.[wikidoc.org]
  • For management of the disease, non-steroidal anti-inflammatory drugs, corticosteroids and colchicine are used, generally with good results, but some patients persist with recurrent episodes of arthritis.[ard.bmj.com]
Joint Effusion
  • […] of the medical term "hydrarthrosis" is presented, which means joint effusion.[connection.ebscohost.com]
  • ., M.D. [1] Synonyms and keywords: Overview Intermittent hydrarthrosis [1] is an rare syndrome affecting women that is characterized by symmetric joint effusions, predominantly involving the knees, without joint destruction.[wikidoc.org]
  • effusions which recur at regular intervals; one or both knee-joints are usually affected, but occasionally other joints such as the hip, ankle, or elbow are involved Intermittent hydrarthrosis.[orthopaedicweblinks.com]
  • Get Social Submit your Twitter account related to Intermittent Joint Effusion to be featured! Blogs Submit your blog on Intermittent Joint Effusion to be featured! Events Submit your event on Intermittent Joint Effusion to be featured![novusbio.com]
  • Signs and symptoms [ edit ] Repeated, periodic joint effusions of the knee. Usually one knee is affected but sometimes both knees. Other joints may also be involved along with the knee.[en.wikipedia.org]
Joint Swelling
  • ) may be useful to relieve joint swelling and improve range of motion.[en.wikipedia.org]
  • NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases Hypermobile joints (Medical Encyclopedia) Joint pain (Medical Encyclopedia) Joint swelling (Medical Encyclopedia) Joint x-ray (Medical Encyclopedia) Limited range of motion (Medical[icdlist.com]
Knee Effusion
  • Other joints may also be involved along with the knee. Effusions are large, restricting range of motion but significant pain is not a feature. There is usually stiffness.[en.wikipedia.org]
  • Treatment of persistent knee effusions with intra‐articular radioactive gold. Can Med Assoc J 1975 ; 112 : 1085 –9. 7 Wallace SL. Colchicine. Semin Arthritis Rheum 1974 ; 3 : 369 –81. British Society for Rheumatology[academic.oup.com]
Knee Pain
  • The objective here was to compare MRI findings with radiological findings in patients with knee pain and to identify factors that influence the... EFFECTS OF INTRA-ARTICULARINJECTION OF HYALURONAN ON PAPAIN-INDUCED HYDRARTHROSIS OF KNEE IN RABBITS.[connection.ebscohost.com]

Treatment

  • Clear treatment options have yet to be established. NSAIDs and COX2-inhibitors are generally not effective.[en.wikipedia.org]
  • When expressed and frequent exacerbations of the disease after failure of other treatment methods may use radiation therapy. In some cases, surgical treatment - synovectomy.[medicalformat.com]
  • Other possible treatments include pain relievers, keeping the injured area from moving, rehabilitation, and sometimes surgery.[icdlist.com]
  • We report here that low doses of colchicine may be a good option in the treatment of IH.[academic.oup.com]
  • Radiation therapy is used after failure of other treatments. Surgical treatment (synovectomy) is indicated for strong and frequent attacks, but does not guarantee a cure (relapses).[vitamedd.com]

Prognosis

  • The overall prognosis is good and radiographs show no evidence of bony erosions or cartilage loss over time [ 1 , 2 ]. Except in rare cases [ 3 ], no crystals have been documented in samples of synovial fluid from these patients [ 2 ].[academic.oup.com]
  • All 3 patients with IH responded well to treatment at one-year follow-up. [13] Prognosis [ edit ] Once established, periods of remissions and relapse can persist indefinitely.[en.wikipedia.org]
  • The presence of large numbers of “ragocytes,” which are granulocytes that have phagocytized immune complexes, is associated with active RA, and their presence may indicate an unfavorable prognosis in this disease. 4 Reiter’s cells represent cytophagocytic[musculoskeletalkey.com]
  • The prognosis is good with treatment.[basicmedicalkey.com]
  • Today’s Rounds will hopefully help to shed some light on it by discussing: The epidemiology of palindromic rheumatism; The clinical, pathological, and laboratory aspects of the disease; Its genetics; Prognosis and treatment; and Its progression to other[hopkinsarthritis.org]

Etiology

  • Two typical cases of intermittent hydrarthrosis of the knee joint, of diverse etiology, are reported in which apparent cure was obtained following the operative removal of the synovial membrane.[journals.lww.com]
  • They are organised into groups, and further divided into clinical, etiological or histopathological sub-types.[orpha.net]
  • Adam, Mehmet; Yildiz, Zafer; Mete, Gül; Leblebici, Berrin // Turkish Journal of Rheumatology;Mar2009, Vol. 24 Issue 1, p58 Intermittent hydrarthrosis (IH) is a monoarticular disease of unknown etiology, characterized by episodic effusions, and it usually[connection.ebscohost.com]
  • Mehmet Adam, Zafer Yıldız, Gül Mete, Berrin Leblebici Keywords: Intermittent hydrarthrosis, treatment, colchicine Abstract Intermittent hydrarthrosis (IH) is a monoarticular disease of unknown etiology, characterized by episodic effusions, and it usually[archivesofrheumatology.org]
  • Com] They are organised into groups, and further divided into clinical, etiological or histopathological sub- types.[favebafa.cf]

Epidemiology

  • […] sclerosis Heritable pulmonary arterial hypertension Limited cutaneous systemic sclerosis Synonym(s): (no synonyms) Classification (Orphanet): - Rare genetic disease - Rare systemic or rheumatologic disease Classification (ICD10): (no data available) Epidemiological[csbg.cnb.csic.es]
  • Epidemiology [ edit ] Intermittent hydrarthrosis is uncommon and its prevalence is not known.[en.wikipedia.org]
  • Epidemiology see specific rheumatologic disease see ref [3] Genetics see specific rheumatologic disease see ref [5] Clinical-manifestations see specific rheumatologic disease see ref [6,8] Laboratory see specific rheumatologic disease see ref [7] Management[anvita.info]
  • Today’s Rounds will hopefully help to shed some light on it by discussing: The epidemiology of palindromic rheumatism; The clinical, pathological, and laboratory aspects of the disease; Its genetics; Prognosis and treatment; and Its progression to other[hopkinsarthritis.org]
  • Medicine, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, Rotterdam, 3015, CE, The Netherlands (2) Department of Rheumatology, Erasmus MC, University Medical Center, 's-Gravendijkwal 230, Rotterdam, 3015, CE, The Netherlands (3) Department of Epidemiology[arthritis-research.biomedcentral.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology The pathogenesis of Intermittent hydrarthrosis is unknown. An involvement of mastocytes has been reported.[wikidoc.org]
  • Pathophysiology [ edit ] Involvement of mast cells has been reported [7] [8] reflecting a possible immunoallergic aspect to IH. Mattingly suggests that IH may be an unusual variant of rheumatoid arthritis, and some patients may go on to develop RA.[en.wikipedia.org]
  • This started a controversy as to exactly what palindromic rheumatism is and what its pathophysiology represents.[hopkinsarthritis.org]
  • Disseminated gonococcal infection: a prospective analysis of 49 patients and a review of pathophysiology and immune mechanisms. Medicine [Baltimore] . 1983;62:395–406. 5. Cucurull E, Espinoza LR. Gonococcal arthritis.[aafp.org]

Prevention

  • No successful treatment for preventing or aborting the attacks has been documented [ 2 ]. Here we report two cases of IH which responded favourably to low doses of colchicine.[academic.oup.com]
  • Local steroid injections can also reduce fluid accumulation short-term, but do not prevent onset of episodes.[en.wikipedia.org]
  • COPING WITH IMMOBILITY Immobilized patients require meticulous care to prevent complications.[basicmedicalkey.com]
  • Thus, the rapid and accurate diagnosis of a crystal-induced process can serve to prevent a costly and unnecessary sequence of events.[musculoskeletalkey.com]
  • If infection is suspected, urgent consultation and culture should be obtained, and intravenous antibiotics should be administered to prevent rapid joint destruction.[aafp.org]

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