We present the case of a 65-year-old man who presented with symptoms of fever, shortness of breath and a non-productive cough, 2 weeks after initiation of therapy with mesalamine. [ncbi.nlm.nih.gov]

• Guillain-Barré Syndrome

  Our report describes a case of life-threatening interstitial pneumonitis associated with Guillain-Barré syndrome that occurred during the administration of adjuvant trastuzumab. [ncbi.nlm.nih.gov]

The results of an extensive workup for other causes including infections were negative and the final diagnosis was lenalidomide-induced interstitial pneumonitis. [ncbi.nlm.nih.gov]

(eg, HIV, toxoplasmosis), depending on the presentation See Workup for more detail. [emedicine.medscape.com]

A proper and detailed history looking for the occupational exposures, and for signs of conditions listed above is the first and probably the most important part of the workup in patients with interstitial lung disease. [en.wikipedia.org]

• Bilateral Pulmonary Opacities

  This is characterized by acute worsening of dyspnea within 1 month, accompanied by new bilateral pulmonary opacities at imaging without an identifiable cause [ 5, 6 ]. [ajronline.org]

• Lymphopenia

  The features included acute respiratory distress with severe inflammatory reaction; ground-glass opacities and/or consolidations in the upper, anterior and central lung fields on XP/CT; peripheral blood lymphopenia; and diffuse alveolar damage confirmed [ncbi.nlm.nih.gov]

• Abnormal Renal Function

  However, patients with abnormal renal function and those with previous calcineurin inhibitor treatment display a higher incidence. The relationship between pneumonitis and mTOR inhibitor plasma concentrations is not well defined. [ncbi.nlm.nih.gov]

The symptoms and imaging study findings improved after initiating steroid treatment. [ncbi.nlm.nih.gov]

They are classified by their distinct clinical-radiological-pathological features and prognosis. They include idiopathic pulmonary fibrosis; cryptogenic organizing pneumonia; and others [icd9data.com]

OBJECTIVE: Multidisciplinary discussion is essential in establishing the diagnosis of idiopathic pulmonary fibrosis (IPF) and in determining prognosis. CONCLUSION: The CT and histopathologic correlate for IPF is usual interstitial pneumonitis (UIP). [ncbi.nlm.nih.gov]

Prognosis of fibrotic interstitial pneumonia: idiopathic versus collagen vascular disease related subtypes. Am J Respir Crit Care Med, 175 (2007), pp. 705-711 [4] R. Vij, M.E. Strek. [archbronconeumol.org]

Prognosis The prognosis is severe and early mortality is high. The documents contained in this web site are presented for information purposes only. [orpha.net]

Those with less than 5% honeycombing may pose diagnostic difficulty as differentiation from NSIP on imaging can be impossible; however, these still follow similar prognosis as other UIP patients 2 reticular opacities : in the immediate subpleural lung [radiopaedia.org]

Diagnosis can be challenging and is usually made by exclusion of other etiologies. In this report we present two cases of sirolimus-associated pulmonary toxicity with a review of the literature. [ncbi.nlm.nih.gov]

Clinical Information A group of interstitial lung diseases with no known etiology. There are several entities with varying patterns of inflammation and fibrosis. [icd9data.com]

Author information 1 Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark. [email protected] Abstract Chemotherapy and radiation therapy may increase risk for interstitial pneumonitis (IP) in breast cancer patients, but there are [ncbi.nlm.nih.gov]

Summary Epidemiology Prevalence of Acute interstitial pneumonia (AIP) is estimated at 1 in 25,000. Clinical description AIP occurs over a wide age range, with a mean age of approximately 50 years. [orpha.net]

Population-based studies and registries are urgently needed in order to properly understand the epidemiology of ILD in Portugal. [journalpulmonology.org]

[…] acute respiratory distress syndrome (ARDS) attributable to an identifiable cause, as well as patients with underlying fibrotic lung disease or systemic disorders known to be associated with lung involvement such as connective tissue disease. [1, 2] Epidemiology [emedicine.medscape.com]

We either mock-infected or infected the mice with MCMV by intranasal administration and monitored pathophysiological behavior and body weight. [ncbi.nlm.nih.gov]

New insight into the pathophysiology of idiopathic pulmonary fibrosis suggests a distinctly fibroproliferative process, and antifibrotic therapies show promise. [jamanetwork.com]

[…] seen in other etiologies such as connective tissue diseases and hypersensitivity pneumonia IPF was previously called chronic interstitial pneumonitis or cryptogenic fibrosing alveolitis Sites Bottom of lower lobes of bilateral (or "bibasilar") lung Pathophysiology [pathologyoutlines.com]

Simmons Pathophysiology Week 8Respiratory Cases For Discussion Case 8. Fibrosis of lungs results in coughing and shortness of breath, two characteristic features of the disease. [cscsoftware.com]

[…] completion of this activity, participants should be better able to: Recognize the signs and symptoms of systemic sclerosis (SSc) to facilitate earlier diagnosis and treatment to help prevent disease progression, Assess the relationship between disease pathophysiology [player.fm]

Early recognition is important to prevent unnecessary investigations and prolonged morbidity. [ncbi.nlm.nih.gov]

Can interstitial lung disease be prevented? Interstitial lung disease can be prevented only to the extent that its individual causes may be prevented. [medicinenet.com]

Can iritis be prevented? There is not much you can do to prevent iritis. If you have an autoimmune condition, taking your medicines as prescribed may help prevent iritis. [cedars-sinai.org]

The lack of clear uniformity has prevented this group from being categorically accepted as an entity and from being considered as a uniform cohort for resolving key issues regarding these patients. 2 Identifying CTD in a patient under study for an ILD [archbronconeumol.org]