We present a case of a newborn with apple-peel intestinal atresia managed by enteroplasty for intestinal lengthening and primary anastomosis. [ncbi.nlm.nih.gov]

The most common associated conditions are cystic fibrosis, malrotation, and gastroschisis, all of which are present in about 10% of cases. [msdmanuals.com]

• Neonatal Intestinal Obstruction

  Recent reports in the literature have suggested a possible connection between fetal ascites, anemia and dilated bowel with neonatal intestinal obstruction. [ncbi.nlm.nih.gov]

• Eating Problem

  If not diagnosed in utero, infants with intestinal atresia are typically diagnosed at day 1 or day 2 after presenting with eating problems, vomiting, and/or failure to have a bowel movement. [en.wikipedia.org]

• Short Arm

  It is due to a mutation in the gene TTC7A on short arm of chromosome 2 (2p16). It is inherited as an autosomal recessive gene and is usually fatal in infancy. [en.wikipedia.org]

• Vaginal Bleeding

  bleeding frequently complicates the pregnancies. [thehealthscience.com]

  In addition, the atresia is associated with twinning, the parents are more often consanguineous compared with parents of healthy neonates, and vaginal bleeding frequently complicates the pregnancies. [emedicine.medscape.com]

Resection of the affected intestine is the treatment for segmental mesenteric defects. Intestinal mesenteric abnormalities as a cause of intestinal atresia unifies under one etiology all the lesions observed in intestinal atresia. [ncbi.nlm.nih.gov]

Learn about this topic in these articles: Barnard’s surgical treatment In Christiaan Barnard …the first to show that intestinal atresia, a congenital gap in the small intestine, is caused by an insufficient blood supply to the fetus during pregnancy. [britannica.com]

Surgical treatment is ultimately necessary to reestablish intestinal continuity. [clinicaladvisor.com]

The prognosis for infants with jejunoileal atresia is very good with > 90% survival. Prognosis is based on the length of remaining small bowel and the presence of the ileocecal valve. [msdmanuals.com]

This classification generally guides prognosis and therapy (see the image below). Classification of jejunoileal atresias. [emedicine.medscape.com]

Treatment and prognosis Surgical treatment depends on the severity of obstruction and length of the damaged bowel but is usually curative. esophageal atresia duodenal atresia jejunoileal atresia anal atresia Promoted articles (advertising) [radiopaedia.org]

CONCLUSION: In our series the congenital malformations associated with intestinal atresia were determinant in the prognosis and mortality of these patients. [ncbi.nlm.nih.gov]

Therefore, the most likely etiology for duodenal atresia is failure of luminal recanalization after the cord stage. [accesssurgery.mhmedical.com]

BACKGROUND/PURPOSE: The aim of this study was to investigate the possible etiologic factors of small bowel atresia and to detect the prognostic role of adequate resection and tapering in postoperative morbidity and mortality. [ncbi.nlm.nih.gov]

[…] in·tes·ti·nal a·tre·si·a an obliteration of the lumen of the small intestine, with the ileum involved in 50% of cases and the jejunum and duodenum next in frequency; most frequent cause of intestinal obstruction in the newborn; etiology may be related [medical-dictionary.thefreedictionary.com]

Etiology Multiple theories regarding the etiology of jejunoileal atresia have been studied in many animal models (eg, puppies, ewes, rabbits, and chick embryos). [22, 23, 24, 25, 26] Murine studies suggest that some forms of atresia may be hereditary [emedicine.medscape.com]

Epidemiology of small intestinal atresia in Europe: a register-based study Kate E Best 1, Peter W G Tennant 1, Marie-Claude Addor 2, Fabrizio Bianchi 3, Patricia Boyd 4, Elisa Calzolari 5, Carlos Matias Dias 6, Berenice Doray 7, Elizabeth Draper 8, Ester [fn.bmj.com]

The anomalies are organized by anatomical system and presented in a consistent manner, including details of the clinical presentation, epidemiology, embryology, treatment and prevention for each anomaly. [books.google.com]

Epidemiological data and patient characteristics were analyzed and outcomes were compared with those reported in other LMICs and high-income countries (HICs). [ncbi.nlm.nih.gov]

The possible causes and pathophysiology of intestinal atresia are discussed. [ncbi.nlm.nih.gov]

Sleisenger & Fordtran's Gastrointestinal and Liver Disease Pathophysiology / Diagnosis / Management, sixth edition. 1998, Philadelphia: W. B. Saunders Company, pp. 1423-1431. 4. Wyllie R. Chapter 330 - Intestinal Atresia, Stenosis, and Malrotation. [hawaii.edu]

Pathophysiology The pathophysiology of dudoenal stenosis and atresia differs from that of obstructions located more distally in the jejunoileal area; the importance of this difference cannot be overstated. [emedicine.medscape.com]

Another report of different intestinal atresias in identical twins proposes them to be either the consequence of linkage of two genes or a pleiotropic expression of a single gene. [35] Pathophysiology As stated above, the patophysiology of dudoenal stenosis [thehealthscience.com]

Thus, multiple anastomoses may be the appropriate procedure to prevent short-gut syndrome for congenital multiple intestinal atresia, even in premature infants. [ncbi.nlm.nih.gov]

The anomalies are organized by anatomical system and presented in a consistent manner, including details of the clinical presentation, epidemiology, embryology, treatment and prevention for each anomaly. [books.google.com]

Prevention IA can’t be prevented. This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. [denverhealth.org]