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Intestinal Disease


Presentation

  • We present here the methods for a study to determine rates and aetiology of IID in the community, presenting to primary care and recorded in national surveillance statistics.[ncbi.nlm.nih.gov]
  • Herein, a male patient is presented with hypoalbuminemic ascites and a history of chronic diarrhea five years before.[ncbi.nlm.nih.gov]
  • Abstract The authors present a case of colonic monoblastic sarcoma, previously treated for other digestive abnormalities (malabsorbtion, Hirschprung's disease).[ncbi.nlm.nih.gov]
  • PARTICIPANTS: 6836 participants registered with the 88 participating practices in the community study; 991 patients with UK-acquired IID presenting to one of 37 practices taking part in the GP presentation study.[ncbi.nlm.nih.gov]
  • We present a case of vulvovaginal MCD in the setting of well-controlled intestinal disease.[ncbi.nlm.nih.gov]
Weight Loss
  • Abstract A 20-year-old male presented with low-grade fever, abdominal pain, anorexia, and weight loss of 4-month duration. On examination, he was emaciated.[ncbi.nlm.nih.gov]
  • Abstract Celiac disease is a gluten-dependent small intestinal mucosal disorder that causes malabsorption, often with diarrhea and weight loss.[ncbi.nlm.nih.gov]
  • Return to euglycemia and normal insulin levels are observed within days after surgery, suggesting that weight loss alone cannot entirely explain why surgery improves diabetes.[ncbi.nlm.nih.gov]
  • Diagnosis was based on typical clinical features [diarrhoea (7/7), weight loss (7/7), clubbing (6/7), fever (3/7), abdominal pain and lump (3/7)], biochemical evidence of malabsorption and duodenal biopsy findings.[ncbi.nlm.nih.gov]
  • It causes pain after eating and results in weight loss. It can also result in a fatal interruption of blood-flow to the intestines. Without proper flow, the intestines may begin to die and become gangrenous.[ucdmc.ucdavis.edu]
Turkish
  • Abstract We describe a 30-year-old woman of Turkish descent presenting with abdominal pain and signs of malabsorption.[ncbi.nlm.nih.gov]
  • We report on a 28 year old Turkish woman, who was admitted to our hospital with the symptoms of malabsorption and protein-loosing enteropathy.[ncbi.nlm.nih.gov]
Abdominal Pain
  • In the 45 patients with small-intestinal ulcer, 29 patients had recurrent hemorrhage, 9 had abdominal pain, 4 had abdominal distention, 2 had malnutrition, and 1 had diarrhea.[ncbi.nlm.nih.gov]
  • CONCLUSION: Abdominal pain is the most common clinical symptom in patients with primary small intestinal disease. Malignant tumors are the most common diseases. Duodenum was the most common part involved in small intestine.[ncbi.nlm.nih.gov]
  • Abstract We describe a 30-year-old woman of Turkish descent presenting with abdominal pain and signs of malabsorption.[ncbi.nlm.nih.gov]
  • Abstract A 20-year-old male presented with low-grade fever, abdominal pain, anorexia, and weight loss of 4-month duration. On examination, he was emaciated.[ncbi.nlm.nih.gov]
  • Most patients (68.8%) presented with abdominal pain and diarrhoea. In the majority (62.5%), duodenum was the primary site of involvement. Endoscopy showed polypoidal, raised or flat lesions.[ncbi.nlm.nih.gov]
Constipation
  • Constipation and irritable bowel syndrome (IBS) are two common examples.[my.clevelandclinic.org]
  • Functional constipation and chronic functional abdominal pain are other disorders of the intestine that have physiological causes, but do not have identifiable structural, chemical, or infectious pathologies.[doctors-hospitals-medical-cape-town-south-africa.blaauwberg.net]
  • Here are some other symptoms: Abdominal pain after eating Weight loss Avoidance of eating Diarrhea, constipation, or vomiting Acute If an artery to the intestines becomes acutely blocked, the primary symptom is severe and widespread abdominal pain.[ucdmc.ucdavis.edu]
Nausea
  • When the abdomen receives radiation, there is always some nausea, vomiting, and diarrhea. In most cases, the symptoms get better within 2 to 3 months after treatment ends.[nlm.nih.gov]
  • Drugs that are effective against nausea and vomiting (antiemetics) may also be used. Prokinetics are a class of drugs that are often prescribed to individuals with CIP with the intent of improving gastrointestinal motility.[rarediseases.org]
  • The standard treatment for C. diff infection, which can cause abdominal pain, severe diarrhea, dehydration, nausea and kidney failure, is actually more antibiotics.[sacbee.com]
  • Silverman, MD Nausea, Vomiting and Dyspepsia – Brian E.[patients.gi.org]
Loss of Appetite
  • Loss of appetite and weight loss also may occur. However, the disease is not always limited to the gastrointestinal tract; it can also affect the joints, eyes, skin, and liver. Fatigue is another common complaint.[rxlist.com]
  • Note : Crohn’s disease and ulcerative colitis can have similar symptoms and may include: Severe abdominal pain Diarrhea (often with blood, mucus, and/or pus) Painful bowel movements Fever Fatigue Loss of appetite and weight loss What are Conventional[lifeextension.com]
  • Symptoms generally include frequent, watery diarrhea, loss of appetite, stomach cramps, bloating and fatigue. Vomiting, body aches, headache, fever and other flu-like symptoms are possible.[mystatesman.com]
  • […] of appetite Nausea and vomiting Most of the time, these symptoms get better within 2 to 3 months after radiation treatment ends.[nlm.nih.gov]
  • Symptoms often include pain, skin rash, acid reflux, anemia, diarrhea, stomach cramps, bleeding, nausea, vomiting, loss of appetite, blood loss in stools, and choking.[rarediseases.info.nih.gov]
Chronic Diarrhea
  • Herein, a male patient is presented with hypoalbuminemic ascites and a history of chronic diarrhea five years before.[ncbi.nlm.nih.gov]
  • Collectively, these results suggest that NanI may contribute to the intestinal attachment and colonization needed for the chronic diarrhea of CPE-associated AAD and SD, but this sialidase appears to be dispensable for the acute pathogenesis of type A[ncbi.nlm.nih.gov]
  • It is characterized by inflammation of the small intestine, loss of microvilli structure, deficient nutrient absorption, and malnutrition.Human immunodeficiency virus (HIV) HIV EnteropathyCharacterized by chronic diarrhea more than one month in duration[en.wikipedia.org]
  • Chronic diarrhea and protein-losing gastroenteropathy caused by Dientamoeba fragilis. J Gastroenterol. 2004 Nov. 39(11):1117-9. [Medline]. Murali A, Narasimhan D, Krishnaveni J, Rajendiran G.[emedicine.com]
  • Symptoms of GI disorders often include cramping, abdominal pain, inflammation of the lining of the large and/or small intestine, chronic diarrhea, rectal bleeding and weight loss.[norml.org]
Periodontitis
  • While this is a relatively rare condition, it (as well as other disorders of the immune system) provides a useful insight into the role that the immune system plays in the inflammatory periodontal diseases.[ncbi.nlm.nih.gov]
  • Historically, C. concisus was associated with the human oral cavity and has been linked with periodontal lesions, including gingivitis and periodontitis, although currently its role as an oral pathogen remains contentious.[ncbi.nlm.nih.gov]
Papule
  • A variety of clinical presentations have been described, including widespread nonspecific pain and swelling, erythematous papules and plaques, and nonhealing ulcers.[ncbi.nlm.nih.gov]

Workup

  • The workup and treatment of diarrhea is similar in patients with or without diabetes.[journal.diabetes.org]
  • Coverage begins with the patient's first visit and proceeds through the diagnostic workup: endoscopy, radiologic testing, and instruments for rating and classifying inflammatory bowel disease.[libreriacortinamilano.it]
Hepatic Necrosis
  • Postmortem histopathology in F( ) indicated not only massive hepatic necrosis, but also massive hepatic fibrosis. These histopathological findings explained the clinical presentation of portal hypertension.[ncbi.nlm.nih.gov]
Lymphocytic Infiltrate
  • The first patient had a lymphocytic infiltrate of the lamina propria and lymphoid hyperplasia of the mesenteric lymph nodes and responded to oral tetracycline.[ncbi.nlm.nih.gov]

Treatment

  • Water and Na balance were assessed (weight, serum creatinine, urea, Na) at baseline and at 1 and 3 months of treatment, but also monitored carefully during the first few days of treatment. Serum Mg was measured at baseline and at 2 and 4 weeks.[ncbi.nlm.nih.gov]
  • CONCLUSION: These results suggest that long-term treatment with octreotide LAR may be a safe and effective approach for treatment of small intestinal disease in patients with SSc.[ncbi.nlm.nih.gov]
  • Stage A and B patients responded well to antibiotic treatment (tetracycline) with regression of the lesions while for stage C patients standard CHOP chemotherapy was administered.[ncbi.nlm.nih.gov]
  • Treatment with a low fat diet, supplemented with medium chain triglycerides (MCT), resulted in a disappearance of the symptoms and normal growth.[ncbi.nlm.nih.gov]
  • The patient responded well to an extended treatment with tetracycline and eradication of H. pylori.[ncbi.nlm.nih.gov]

Prognosis

  • […] research found that smoking increases the risk of Crohn’s disease by about 76%. 9 In Australia, about 36% of Crohn’s disease in men, and about 40% in women, has been attributed to smoking. 10 Patients with Crohn's disease who continue to smoke have a worse prognosis[tobaccoinaustralia.org.au]
  • Prognosis A retrospective study by John et al indicated that the survival rate has increased for patients who develop protein-losing enteropathy as a complication of the Fontan procedure, an operation for the treatment of several types of congenital heart[emedicine.com]
  • Cannabis use provides symptom relief in patients with inflammatory bowel disease but is associated with worse disease prognosis in patients with Crohn’s disease. Inflammatory Bowel Diseases 20: 472-480. [8] Weiss and Friedenberg. 2015.[norml.org]
  • Clinical manifestations, diagnosis, and prognosis of ulcerative colitis in adults. . Accessed July 7, 2017. What is colorectal cancer screening? Centers for Disease Control and Prevention. . Accessed May 12, 2017. Feldman M, et al.[mayoclinic.org]

Etiology

  • Intestinal Perforation/etiology Muscle, Smooth/pathology Practice Guidelines as Topic Risk Factors Rupture, Spontaneous[ncbi.nlm.nih.gov]
  • AIM: To evaluate the major clinical symptom, etiology, and diagnostic method in patients with primary small intestinal disease in order to improve the diagnosis.[ncbi.nlm.nih.gov]
  • To evaluate the diagnostic significance of CMV detection by PCR in fecal samples, patients were classified according to the etiology of their intestinal disease (based on results of endoscopy, histopathology and quantitative CMV DNA detection in biopsies[ncbi.nlm.nih.gov]
  • We examined changes in etiology and diagnostic yield of IID cases over 15 years.[ncbi.nlm.nih.gov]
  • […] builder options Subheadings: analysis anatomy and histology blood cerebrospinal fluid chemically induced classification complications congenital diagnosis diagnostic imaging diet therapy drug therapy economics embryology enzymology epidemiology ethnology etiology[ncbi.nlm.nih.gov]

Epidemiology

  • , Newborn Infant, Premature, Diseases/diagnosis Infant, Premature, Diseases/epidemiology* Infant, Premature, Diseases/etiology Infant, Very Low Birth Weight Intestinal Mucosa/pathology Intestinal Perforation/diagnosis Intestinal Perforation/epidemiology[ncbi.nlm.nih.gov]
  • Although there is limited epidemiologic evidence to confirm this, we suggest that a link between air pollution and intestinal disease exists and warrants further study.[ncbi.nlm.nih.gov]
  • During the initial 3-year epidemiologic collaboration, CDC laboratory workers and epidemiologists worked to improve detection tools and epidemiologic methods to study the role of infections (infectious disease epidemiology) in pediatric IBD, collaborating[rxlist.com]
  • Abstract We reviewed the epidemiological and microbiological characteristics of 89 reported outbreaks of waterborne infectious intestinal disease affecting 4321 people in England and Wales over the period 1992-2003.[ncbi.nlm.nih.gov]
  • Preliminary recent epidemiological data have shown a decrease in the incidence of this disease in endemic areas, and therefore environmental factors are suspected to play a major role in its pathogenesis.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • Detailed information describing the mechanisms by which altered cytokine signaling occurs is not available, but recent data implicate the cytoskeleton within epithelial cells as a critical regulator of the mucosal barrier under physiological and pathophysiological[ncbi.nlm.nih.gov]
  • Recent experimental studies point toward the rearrangement of gastrointestinal anatomy as a primary mediator of the surgical control of diabetes, suggesting a role of the small bowel in the pathophysiology of the disease.[ncbi.nlm.nih.gov]
  • Sleisenger & Fordtran's gastrointestinal and liver disease : pathophysiology, diagnosis, management / [edited by] Mark Feldman, Lawrence S. Friedman, Lawrence J. Brandt.—8th ed. Publisher Saunders an imprint of Elsevier, Philadelphia, PA.[rxlist.com]
  • It is not a single disease, but an atypical manifestation of other diseases. [2] Pathophysiology The pathophysiology of this disorder is directly related to the excessive leakage of plasma proteins into the lumen of the gastrointestinal tract.[emedicine.com]
  • The presenting symptoms of these two IBDs are often similar (abdominal pain, vomiting, diarrhoea), but the pathophysiology differs. Crohn's disease is thought to be an autoimmune disease (see Section 3.17 ), but ulcerative colitis is not.[tobaccoinaustralia.org.au]

Prevention

  • Glucagon-like peptide-2 (GLP-2) is a potent and specific gastrointestinal growth factor that is demonstrating therapeutic potential for the prevention or treatment of an expanding number of intestinal diseases, including short bowel syndrome (SBS), small[ncbi.nlm.nih.gov]
  • Private water suppliers need to be aware of the importance of adequate treatment and the prevention of faecal contamination of storage water.[ncbi.nlm.nih.gov]
  • Other therapeutic targets that represent strategies to prevent or reverse disease processes are also considered.[ncbi.nlm.nih.gov]
  • BACKGROUND: Infectious intestinal disease (IID), usually presenting as diarrhoea and vomiting, is frequently preventable. Though often mild and self-limiting, its commonness makes IID an important public health problem.[ncbi.nlm.nih.gov]
  • Vomiting Dangers, Complications and How To Prevent It Vomiting is the body’s natural mechanism for getting rid of harmful substances and irritants in the upper gut (esophagus, stomach and upper part of the small intestine).[healthhype.com]

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