Presentation
A predisposing factor was present in all patients in the form of corticosteroid intake, chronic liver disease and panhypogammaglobulinaemia. [ncbi.nlm.nih.gov]
Retrieved from PLOS CC BY 4.0 (https://creativecommons.org/licenses/by-sa/4.0/legalcode) Here, we present the pulmonary manifestations and radiological findings of severe strongyloidiasis. [collinsdictionary.com]
Intestinal strongyloidiasis presenting with pneumobilia and partial duodenal obstruction. Am J Gastroenterol. 2002;97(9 Suppl):S211-2.). [scielo.br]
Entire Body System
- Weakness
Four weeks after therapy was initiated, the muscle weakness and dyspnea were worse and there was progression of the pulmonary infiltrates. [nejm.org]
Our patient complained of epigastric pain associated with nausea, vomiting and general weakness. [kjim.org]
Some people may experience, nausea, vomiting, weight loss, weakness or constipation. In chronic infections skin and chest symptoms can persist. The time from infection until a person might develop symptoms is variable. [nt.gov.au]
Weight loss, anorexia, and weakness may develop. The clinical presentation may resemble peptic ulceration, giardiasis, hookworm disease, amebiasis, or sprue with loss of weight, fat, protein, and electrolytes. [isradiology.org]
As part of the hyperinfection syndrome in immunocompromised patients, central nervous system (CNS) involvement may be manifest by headache, altered mentation, meningismus, focal or generalized seizures, or motor weakness. [infectiousdiseaseadvisor.com]
Respiratoric
- Pneumonia
An S. stercoralis infection can cause the following complications: Eosinophilic pneumonia Eosinophilic pneumonia occurs when your lungs swell due to an increase in eosinophils. [healthline.com]
These can vary from an innocuous cough and mild hemoptysis to occasional frank pneumonia or asthma. [isradiology.org]
Dis., 5, Seite 488 - C., and Gibert, C., Nosocomial pneumonia in patients receiving continuous mechanical ventilation: prospective analysis of 52 episodes with use of a protected specimen brush and quantitative culture techniques, Am. Rev. [books.google.de]
Specific Code intestinal B78.0 ICD-10-CM Codes Adjacent To B78.0 B76.8 Other hookworm diseases B76.9 Hookworm disease, unspecified B77 Ascariasis B77.0 Ascariasis with intestinal complications B77.8 Ascariasis with other complications B77.81 Ascariasis pneumonia [icd10data.com]
Gastrointestinal
- Vomiting
Children with diarrhoea, who vomit or refuse fluids should see a doctor. Anyone with prolonged or severe diarrhoea, or who is concerned, should see a doctor. [nt.gov.au]
Common gastrointestinal symptoms were abdominal pain, diarrhoea, gastrointestinal bleeding, nausea, vomiting and weight loss with evidence of malabsorption. [ncbi.nlm.nih.gov]
Patient 1 – This patient complained of nausea and intermittent postprandial vomiting, for approximately two months, accompanied by mild abdominal pain, diarrhea, and weight loss. [scielo.br]
- Dyspepsia
He had complaints of dyspepsia since 2000 and was receiving intermittent treatment with H-2 blockers (ranitidine) and occasionally by proton pump inhibitor, (omiprazole). [omjournal.org]
- Intestinal Perforation
In the small intestine, the larvae mature into adult female worms (2–3 mm long) and penetrate the mucosa of the proximal small intestine, where they can lay up to 40 eggs a day. This occurs 17–28 days after the initial infection. [racgp.org.au]
- Abdominal Bloating
The large spectrum of clinical manifestation and lack of classical clinical syndrome (abdominal pain, bloating, heartburn, intermittent episodes of diarrhea and constipation) makes the final diagnosis of Strongyloidiasis difficult. [omicsonline.org]
Liver, Gall & Pancreas
- Jaundice
He had no anemia or jaundice or cyanosis. Bilateral pedal edema was present. Pulse rate was 88 beats/min, Blood pressure was 110/80 mmHg. [jscisociety.com]
Skin
- Larva Migrans
Around the anus during autoinfection the eruption is linear ( larva currens ), and the larvae moving under the skin cause a severe pruritus. The appearance may mimic the "creeping eruption" of cutaneous larva migrans. [isradiology.org]
Larva currens (creeping infection) is a form of cutaneous larva migrans specific to Strongyloides infection; it results from autoinfection. The eruption usually begins in the perianal region and is accompanied by intense pruritus. [merckmanuals.com]
The larvae may be limited to skin migration (larva migrans). [med-chem.com]
Am J Trop Med Hyg. 1977; 26: 859-865 PubMed Google Scholar Arthur RP Shelley WB Larva currens: distinctive variant of cutaneous larva migrans due to Strongyloides stercoralis. [gastrojournal.org]
"Larva currens; a distinctive variant of cutaneous larva migrans due to Strongyloides stercoralis". A.M.A. Archives of Dermatology. 78 (2): 186–90. doi : 10.1001/archderm.1958.01560080044007. [en.wikipedia.org]
- Dermatitis
Invading larvae cause transient dermatitis. Larvae migrating through the lungs may provoke cough, hemoptysis, and dyspnea, but most infections do not lead to pulmonary symptoms. [histopathology-india.net]
Neurologic
- Headache
Clinical signs and symptoms of severe strongyloidiasis can occur suddenly and involves severe abdominal pain, nausea and vomiting, bloody diarrhoea, coughing up blood, shortness of breath, stiff neck, headache, confusion, fever, chills and skin rash. [dermnetnz.org]
As part of the hyperinfection syndrome in immunocompromised patients, central nervous system (CNS) involvement may be manifest by headache, altered mentation, meningismus, focal or generalized seizures, or motor weakness. [infectiousdiseaseadvisor.com]
He denied having fevers, chills, night sweats, headaches, visual changes, dysphagia, odynophagia, cough, chest pain, dyspnea, orthopnea, edema, bleeding, or recent exposure to antibiotics. A review of systems was otherwise normal. [gastroenterologyandhepatology.net]
Albendazole and thiabendazole have an increased incidence of hepatitis and transaminitis as well as abdominal symptoms and headache compared with ivermectin. [antimicrobe.org]
Treatment
Because the auto-infective larvae are difficult to eradicate, one regimen dose may be in-sufficient and re-treatment of patients on two occasions, at 1 and 2 months after the initial treatment dose was recommended. [ncbi.nlm.nih.gov]
Follow up Serology is currently the best measure of treatment efficacy available as there is a decline in antibody titre after treatment. [refugeehealthguide.org.au]
Management and treatment The treatment of choice is ivermectin. Prophylactic measures revolve around preventing contamination through faeces and wearing shoes. The documents contained in this web site are presented for information purposes only. [orpha.net]
Outlook (Prognosis) With proper treatment, the worms can be killed and full recovery is expected. Sometimes, treatment needs to be repeated. [pennstatehershey.adam.com]
Prognosis
Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Strongyloidiasis from other Diseases Epidemiology and Demographics Risk Factors Screening Natural History, Complications and Prognosis [wikidoc.org]
Clinical observations, with special reference to factors influencing prognosis, Rev. Infect. [books.google.de]
[…] count, the worse the prognosis. [infectiousdiseaseadvisor.com]
Outlook (Prognosis) With proper treatment, the worms can be killed and full recovery is expected. Sometimes, treatment needs to be repeated. [ufhealth.org]
Etiology
Etiology The female nematodes, which measure 2.5 mm in length, live in the small intestine of humans. Eggs laid in the small intestine hatch to release larvae that are normally excreted in the faeces. [orpha.net]
S., Kuo, C., Berger, K., Shuster, JR, Overby, LR, Bradley, DW, and Houghton, M., An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis, Science, 244, 362, 1989. [books.google.de]
The initial step in the evaluation of the patient with hypoproteinemia is to exclude other more common etiologies such as malnutrition, liver, and renal diseases. [jdeonline.in]
Stercoralis is an uncommon etiology for proximal bowel obstruction, high index of suspicion should be exercised in patients presenting as above and recent travel to areas endemic for S. Stercoralis. [omicsonline.org]
Diagnostic and Statistical Manual of Mental Disorders.Official Full-Text Publication: [Etiology and clinical course of urticaria in hospitalized children.] on ResearchGate, the professional network for scientists.Parasite antigenic determinants of antibody [anyvileq.webcindario.com]
Epidemiology
Overview Historical Perspective Classification Pathophysiology Causes Differentiating Strongyloidiasis from other Diseases Epidemiology and Demographics Risk Factors Screening Natural History, Complications and Prognosis Diagnosis History and Symptoms [wikidoc.org]
This review summarizes what is understood about infection by S. stercoralis; its focus will be on the epidemiology, diagnosis, clinical presentation patterns in the immunocompetent and immunocompromised human hosts, and recommended treatment regimens. [ncbi.nlm.nih.gov]
This review summarizes what is understood about infection by S. stercoralis ; its focus will be on the epidemiology, diagnosis, clinical presentation patterns in the immunocompetent and immunocompromised human hosts, and recommended treatment regimens [insights.ovid.com]
Step 1: Define risk category for disseminated strongyloidiasis based on epidemiologic and clinical factors Epidemiologic risk category for Strongyloides exposure/Infection Clinical risk factor for disseminated Strongyloides HTLV-1 Table 1 footnote 1 infection [canada.ca]
Pathophysiology
Overview Historical Perspective Classification Pathophysiology Causes Differentiating Strongyloidiasis from other Diseases Epidemiology and Demographics Risk Factors Screening Natural History, Complications and Prognosis Diagnosis History and Symptoms [wikidoc.org]
The pathophysiology underlying these risk factors, whether disease-related or iatrogenically induced, is a compromised immune system leading to dysfunction of TH-2 helper cells. [ncbi.nlm.nih.gov]
Unlike others on this topic, this text demonstrates how the endoscope incorporates pathophysiology, diagnostic, and treatment modalities into endoscopic practice. [books.google.com]
Prevention
| Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies Case Studies Case #1 [wikidoc.org]
Medicines to prevent vomiting or diarrhoea should not be given, especially to children, except when prescribed by a doctor. Prevention Good hygiene and sanitation is the best way to prevent Strongyloidiasis. [nt.gov.au]
Treatment reference Prevention Prevention of primary Strongyloides infections is the same as for hookworms. [merckmanuals.com]
S. stercoralis infection can generally be prevented through good personal hygiene. In around 50 percent of cases, strongyloidiasis causes no symptoms. [healthline.com]
CATMAT statement on disseminated strongyloidiasis: Prevention, assessment and management guidelines. [canada.ca]