Pterygium (choice C) would present clinically as a wing-like, fleshy conjunctival lesion. Histopathology would show thin epithelium without dysplasia and underlying stromal fibrovascular tissue with solar elastosis. [pathologyoutlines.com]

The most common presenting symptom was foreign body sensation (57.1%) with a mean duration of 2.3 +/- 3.8 months. Six patients had pathologically proven CCIN (85.7%) and 1 had SCC (14.3%). [pubmed.ncbi.nlm.nih.gov]

• Keratosis

  Grade 3 / severe dysplasia Grade 2 / moderate dysplasia   Carcinoma in situ Actinic keratosis carcinoma in situ Contributed by Frederick A. Jakobiec, M.D., D.Sc., Deepali Jain, M.D. and Hans Grossniklaus, M.D.   [pathologyoutlines.com]

Topical 0.002% mitomycin C for the treatment of conjunctival-corneal intraepithelial neoplasia and squamous cell carcinoma Pinnita Prabhasawat et al. Cornea. 2005 May. [pubmed.ncbi.nlm.nih.gov]

Two of the 89 eyes treated (2.25%) had only a partial response to treatment; of these 2 patients, 1 was taking cyclosporine for keratitis sicca. [aianmodena.org]

Rep 2019;14:98) 56 year old woman with conjunctival intraepithelial neoplasia presented as a pigmented conjunctival lesion (Case Rep Ophthalmol 2021;12:77) Man with conjunctival lesion and history of basal cell carcinoma (Ophthalmology 2015;122:1039) Treatment [pathologyoutlines.com]

[…] while diffuse growth pattern has poorer prognosis with more recurrences because tumoral margin is not well defined Case reports 41 year old HIV positive man with low CD4 counts presented with conjunctival epithelial dysplasia and viral retinitis (Indian [pathologyoutlines.com]

[…] ocular surface ectoderm Preferred limbal location suggests that most cases arise from limbal stem cells; limbal stem cells are sensitive to oncogenic factors and are susceptible to DNA alterations secondary to UV light Reference: Exp Eye Res 2014;129:172 Etiology [pathologyoutlines.com]

[…] corneal epithelium, including squamous cell carcinoma ICD coding ICD-O: 8077/2 - conjunctival squamous intraepithelial neoplasia (conjunctival intraepithelial neoplasia and carcinoma in situ) ICD-10: C69.00 - malignant neoplasm of unspecified conjunctiva Epidemiology [pathologyoutlines.com]

[…] the bulbar conjunctiva in the interpalpebral fissure (sun exposed area) arising at the limbus (where stem cells reside) Can spread onto the cornea Occasionally occurs in the forniceal or palpebral conjunctiva Reference: Am J Ophthalmol 2017;173:106 Pathophysiology [pathologyoutlines.com]