Presentation
A 54-y-o woman presented to the Emergency Department with shortness of breath and sore throat after intranasal administration of Ecbalium elaterium as a folk remedy for her sinusitis. [ncbi.nlm.nih.gov]
The composite data from individual runs presented in Table 10. [patents.google.com]
Entire Body System
- Burning Pain
Intranasal tolerability rating scales (discomfort, itching, burning, pain, runny nose, and stuffiness) and intranasal endoscopy were conducted. Safety assessments included adverse events, vital signs, pulse oximetry (SpO2), and electrocardiograms. [ncbi.nlm.nih.gov]
Musculoskeletal
- Foot Disease
[…] as influenza, meningitis, pneumonia and as veterinary vaccine carriers for the protection of animals from encephalomyelitis and mouth to foot disease. [ncbi.nlm.nih.gov]
Face, Head & Neck
- Epistaxis
A. copious nasal secretions B. epistaxis C. nasal polyp D. all of the above Question 4 The best absorption of intranasal medication occurs when to a single nostril one delivers volumes less than A. 1 mL. B. 0.5 mL. C. 0.3 mL. D. 0.1 mL. [medium.com]
Tranexamic Acid While not technically intranasal in the sense we have been discussing, the new kid on the block for many EMS providers, TXA applied to a pledget was better than anterior nasal packing in the initial treatment of idiopathic anterior epistaxis [prehospitalresearch.eu]
Neurologic
- Motor Symptoms
MPTP model and to highlight recent findings from our group showing its potential as a valuable rodent model for testing novel drugs that may provide alternative or adjunctive treatment for both motor and non-motor symptoms relief with a reduced side-effect [ncbi.nlm.nih.gov]
- Neuralgia
As a result, potential CNS applications include neurodegenerative conditions such as Parkinson’s disease, ALS (amyotrophic lateral sclerosis), multiple sclerosis, seizures, tumors, vascular conditions, cluster headaches, trigeminal neuralgia, autoimmune [aegisthera.com]
Workup
HLA Type
- HLA-DQ2
Abstract The mucosal lesion in coeliac disease (CD) is an immune-mediated injury triggered by gliadin and associated with HLA-DQ2 and HLA-DQ8. [ncbi.nlm.nih.gov]
Treatment
RESULTS: During the treatment period the DAS28 decreased similarly for all treatment groups-including placebo-indicating lack of efficacy of intranasal HC gp-39 treatment in the current setting. Safety variables were similar for all study groups. [ncbi.nlm.nih.gov]
Prognosis
Patients with good therapeutic response showed reduction of tumor size and PTBE area, but poor prognosis was associated with lack of response to treatment and persistence of high PTBE. [ncbi.nlm.nih.gov]
Tadao Kishimoto, Takashi Shimazaki, Jun Yoshida, Osamu Isurugi, Koichiro キーワード: Administration, Intranasal Aged Aged, 80 and over Buserelin/administration & dosage/therapeutic use Drug Evaluation Humans Male Middle Aged Multicenter Studies as Topic Prognosis [repository.kulib.kyoto-u.ac.jp]
Etiology
We reviewed literature pertaining to the etiology, pharmacology, and pathophysiology of neurologic complications resulting from heroin intoxication. [ncbi.nlm.nih.gov]
Epidemiology
Clinical and epidemiological research Intranasal administration of recombinant human cartilage glycoprotein-39 as a treatment for rheumatoid arthritis: a phase II, multicentre, double-blind, randomised, placebo-controlled, parallel-group, dose-finding [ard.bmj.com]
A prospective, population-based study of the demographics, epidemiology, management, and outcome of out-of-hospital pediatric cardiopulmonary arrest. Ann Emerg Med. [books.google.it]
Pathophysiology
We reviewed literature pertaining to the etiology, pharmacology, and pathophysiology of neurologic complications resulting from heroin intoxication. [ncbi.nlm.nih.gov]
Clinical studies suggest that altered OXT signaling in particular may play a pathophysiological role in mental and developmental disorders characterized by social dysfunction, such as autism, borderline personality disorder, schizophrenia, and social [content.iospress.com]
Prevention
S-IgA antibodies are highly effective at preventing virus infection. [ncbi.nlm.nih.gov]
Aftercare information Contact information for getting naloxone refills Overdose prevention programs have created many great brochures and educational pamphlets. [harmreduction.org]