We present a case of intraneural perineurioma affecting multiple nerves, which usually involved one or two of major nerve trunks in one patient. [ncbi.nlm.nih.gov]

• Fishing

  One perineurioma was subject to tissue culture and cytogenetic study and another to fluorescence in situ hybridization (FISH) analysis. The patients, 3 males and 5 females, ranged in age from 11 to 38 years. [ncbi.nlm.nih.gov]

  In another case, 53% of interphase nuclei showed three FISH signals with a chromosome 14/22 probe, thus suggesting either monosomy for the centromere of chromosome 14 or that of chromosome 22. [doi.org]

  The FISH probe applied to each specimen localize to the DiGeorge/TUPLE1 gene regions located at 22q11.21 and the ARSA gene region located at 22q13. The tissues were probed and analyzed according to their marked H&E slides. [n.neurology.org]

• Localized Pain

  On followup evaluation one week after surgery, the patient had improved hand strength and developed a small area of localized pain over the thumb. Figure 2. 18-year-old female with intraneural perineurioma. [cyberleninka.org]

• Skin Lesion

  Only one case report of the cutaneous form of intraneural perineurioma has been published. [2] Our report describes a 33-year-old woman who presented to the Dermatology Department with asymptomatic skin lesions on her right second and third fingers which [ijdvl.com]

• Tinel's Sign

  A progressive radial neuropathy of unknown etiology despite 1.5T magnetic resonance imaging (MRI) and surgical exploration was identified as an intraneural perineurioma by a localized Tinel's sign, an enlarged radial nerve at the spiral groove by 3.0T [ncbi.nlm.nih.gov]

• Cesarean Section

  A scheduled elective cesarean section under general anesthesia was concluded for the patient under preoperative multidisciplinary consultation with anesthesiologist, neonatologist, and neurologist. [ncbi.nlm.nih.gov]

• Unstable Gait

  A 59-year-old woman presented with a long history of dizziness, tinnitus, hearing loss, and unstable gait. A magnetic resonance imaging scan revealed a small intrameatal lesion, which showed no clear progression from 2000 to 2006. [ncbi.nlm.nih.gov]

• Cranial Neuropathy

  Only rarely does intraneural perineurioma present as a cranial neuropathy. 1 Intracranial meningioma may rarely be associated with cranial mononeuropathies. 2 To our knowledge, prior cases of multiple peripheral and cranial mononeuropathies, with pathologic [neupsykey.com]

• Febrile Seizures

  Her medical history was significant only for a febrile seizure at 1 year of age. There was no personal or family history of neurofibromatosis (NF) or other inheritable neuropathies. [archivesofpathology.org]

[…] duration of symptoms prior to diagnosis, treatment modalities and outcomes measures, follow-up assessment for tumor recurrence and metastasis, clinical features (history of trauma, motor/sensory abnormalities, clinical/family history), and diagnostic workup [ncbi.nlm.nih.gov]

The second patient is an 11-year-old female whose treatment highlights some of the controversy surrounding the management of these lesions, and the importance of thorough macroscopic and microscopic assessment by pathologists, including the status of [ncbi.nlm.nih.gov]

As intraneural perineurioma is rarely known to arise in the brachial plexus, principles of its surgical treatment have not been formulated thus far. [doi.org]

Eighteen patients were operated for excision biopsy and/or palliative treatment for their motor deficit. [panafrican-med-journal.com]

What is the Prognosis of Intraneural Perineurioma? (Outcomes/Resolutions) In some cases, Intraneural Perineurioma may be asymptomatic and these tumors may not require any treatment. [dovemed.com]

Treatment and prognosis Soft tissue perineuriomas can usually be cured with resection, although local recurrence and metastasis are described in malignant tumors 1. [radiopaedia.org]

In our series it was of little help as most of patients showed non specific enlargement (Figure 1, Figure 2) Intraneural perineurioma management is contraversial, due to its natural history and long term prognosis. [panafrican-med-journal.com]

A progressive radial neuropathy of unknown etiology despite 1.5T magnetic resonance imaging (MRI) and surgical exploration was identified as an intraneural perineurioma by a localized Tinel's sign, an enlarged radial nerve at the spiral groove by 3.0T [ncbi.nlm.nih.gov]

Sural nerve biopsy showed an intraneural perineurioma on the right side and a severe axonal damage without indicating an inflammatory etiology on the left side. [thieme-connect.com]

Localized hypertrophic neuropathy, also termed intraneural perineurioma, is a rare disorder of unknown etiology that produces a slowly progressive painless focal lesion of a peripheral nerve. [ndorms.ox.ac.uk]

The aim of our study is to present the epidemiology, clinical presentation, way of diagnosis and management plan in a consecutive patient series. Ninteen patients diagnosed as having intraneural perineurioma were retrospectively chart reviewed. [cuidadospaliativos.info]

The aim of our study was to present the epidemiology, clinical presentation, way of diagnosis and management plan in a consecutive patient series. [panafrican-med-journal.com]

The epidemiology of perineuriomas depends on their location. Soft tissue perineuriomas occur in adults and are more frequent in females (M:F 2:1) 1. [radiopaedia.org]

Epidemiology Perineuromas over a wide age range. T hey have variously been reported to show a female predominance 5 or to occur with equal frequency in men and women. Intestinal cases may be more common in women 3. [e-immunohistochemistry.info]

Resection and nerve graft reconstruction were performed to prevent progression of motor compromise and to allow recovery of motor function. An algorithm for the management of focal intraneural tumors is shown. [utsouthwestern.influuent.utsystem.edu]

Surgical management includes excision to prevent progression of palsy and placement of a nerve graft if clinically indicated. A 28-year-old woman presented with a 2-year history of progressive painless right peroneal nerve palsy. [ncbi.nlm.nih.gov]