We present a case of intraneural perineurioma affecting multiple nerves, which usually involved one or two of major nerve trunks in one patient.[ncbi.nlm.nih.gov]
Clinical and pathological findings of a perineurioma involving the ulnar nerve is presented. A 7-year-old girl presented with a 2 year history of weakness and atrophy of the right hand muscles.[ncbi.nlm.nih.gov]
In our report, we present the first case of cutaneous intraneural perineurioma, a benign tumor, which expands the morphological spectrum of cutaneous neural lesions.[ncbi.nlm.nih.gov]
The authors describe the clinical presentation, magnetic resonance (MR) neurography characteristics, and pathological characteristics of a perineurioma involving the peroneal nerve.[ncbi.nlm.nih.gov]
To our knowledge this is the third example of an intraneural perineurioma that did not present in a major nerve.[ncbi.nlm.nih.gov]
One perineurioma was subject to tissue culture and cytogenetic study and another to fluorescence in situ hybridization (FISH) analysis. The patients, 3 males and 5 females, ranged in age from 11 to 38 years.[ncbi.nlm.nih.gov]
In another case, 53% of interphase nuclei showed three FISH signals with a chromosome 14/22 probe, thus suggesting either monosomy for the centromere of chromosome 14 or that of chromosome 22.[doi.org]
In addition, absence of the BCR region of chromosome 22 and expression of the BCR-ABL fusion gene were observed by fluorescent in situ hybridization (FISH), and a chromosome 22 abnormality was confirmed.[ncbi.nlm.nih.gov]
The FISH probe applied to each specimen localize to the DiGeorge/TUPLE1 gene regions located at 22q11.21 and the ARSA gene region located at 22q13. The tissues were probed and analyzed according to their marked H&E slides.[n.neurology.org]
A 58-year-old woman was referred for the surgical management of a right axillarymass that was incidentally noted on ultrasonography. The tumor had already been diagnosed as a spindle cell tumor from an ultrasound-guided biopsy.[doi.org]
Access this article online Quick Response Code: Website: www.ijdvl.com DOI: 10.4103/0378-6323.129412 PMID: 129412 Mondor’s disease Sir, Henry Mondor first described superficial vein thrombosis involving the subcutaneous veins of the anterolateral thoracoabdominal[docksci.com]
A progressive radial neuropathy of unknown etiology despite 1.5T magnetic resonance imaging (MRI) and surgical exploration was identified as an intraneural perineurioma by a localized Tinel'ssign, an enlarged radial nerve at the spiral groove by 3.0T[ncbi.nlm.nih.gov]
Review of the principal extra spinal pathologies cause of sciatica and new approach by MRI. Br J Radiol. 2012;85(1014):672–81. PubMed CrossRef Google Scholar 15. Woertler K. Tumors and tumor-like lesions of peripheral nerves.[link.springer.com]
A 59-year-old woman presented with a long history of dizziness, tinnitus, hearing loss, and unstablegait. A magnetic resonance imaging scan revealed a small intrameatal lesion, which showed no clear progression from 2000 to 2006.[ncbi.nlm.nih.gov]
Only rarely does intraneural perineurioma present as a cranialneuropathy. 1 Intracranial meningioma may rarely be associated with cranial mononeuropathies. 2 To our knowledge, prior cases of multiple peripheral and cranial mononeuropathies, with pathologic[neupsykey.com]
In very young patients, weakness might be attributed to birth trauma or a perinatal stroke. Although the tumors are most common in childhood and early adulthood, Mayo Clinic neurologists have seen patients with disease onset occurring after age 50.[mayoclinic.org]
[…] duration of symptoms prior to diagnosis, treatment modalities and outcomes measures, follow-up assessment for tumor recurrence and metastasis, clinical features (history of trauma, motor/sensory abnormalities, clinical/family history), and diagnostic workup[ncbi.nlm.nih.gov]
The second patient is an 11-year-old female whose treatment highlights some of the controversy surrounding the management of these lesions, and the importance of thorough macroscopic and microscopic assessment by pathologists, including the status of[ncbi.nlm.nih.gov]
Because of the small number of cases, no consensus has been made on proper treatment of this entity.[ncbi.nlm.nih.gov]
Treatment consisted of biopsy in six cases and resection in two cases. Histologically, pseudo-onion bulbs composed of epithelial membrane antigen-reactive, S-100 protein-negative perineurial cells surrounded myelinated or nonmyelinated nerve fibers.[ncbi.nlm.nih.gov]
(Outcomes/Resolutions) In some cases, Intraneural Perineurioma may be asymptomatic and these tumors may not require any treatment.[dovemed.com]
What is the Prognosis of Intraneural Perineurioma? (Outcomes/Resolutions) In some cases, Intraneural Perineurioma may be asymptomatic and these tumors may not require any treatment.[dovemed.com]
Efficiently review the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, differential diagnosis, therapy, and prognosis for virtually every pathologic entity.[books.google.es]
In our series it was of little help as most of patients showed non specific enlargement (Figure 1, Figure 2) Intraneural perineurioma management is contraversial, due to its natural history and long term prognosis.[panafrican-med-journal.com]
Treatment and prognosis Soft tissue perineuriomas can usually be cured with resection, although local recurrence and metastasis are described in malignant tumors 1 .[radiopaedia.org]
A progressive radial neuropathy of unknown etiology despite 1.5T magnetic resonance imaging (MRI) and surgical exploration was identified as an intraneural perineurioma by a localized Tinel's sign, an enlarged radial nerve at the spiral groove by 3.0T[ncbi.nlm.nih.gov]
Localized hypertrophic neuropathy, also termed intraneural perineurioma, is a rare disorder of unknown etiology that produces a slowly progressive painless focal lesion of a peripheral nerve.[ncbi.nlm.nih.gov]
The etiology is idiopathic, and it is controversial whether the process is reactive or neoplastic. All previously reported cases have involved major nerves and have been associated with motor deficits and, less frequently, sensory signs or symptoms.[ncbi.nlm.nih.gov]
Sural nerve biopsy showed an intraneural perineurioma on the right side and a severe axonal damage without indicating an inflammatory etiology on the left side.[thieme-connect.com]
The aim of our study was to present the epidemiology, clinical presentation, way of diagnosis and management plan in a consecutive patient series.[panafrican-med-journal.com]
The epidemiology of perineuriomas depends on their location. Soft tissue perineuriomas occur in adults and are more frequent in females (M:F 2:1) 1 .[radiopaedia.org]
The epidemiology of perineuriomas depends on their location. Soft tissue perineuriomas occur in adults and are more frequent in females (M:F 2:1) 1.[radiopaedia.org]
Epidemiology Perineuromas over a wide age range. T hey have variously been reported to show a female predominance 5 or to occur with equal frequency in men and women. Intestinal cases may be more common in women 3.[e-immunohistochemistry.info]
Epidemiology Perineuromas over a wide age range . T hey have variously been reported to show a female predominance 5 or to occur with equal frequency in men and women. Intestinal cases may be more common in women 3 .[e-immunohistochemistry.info]
Surgical management includes excision to prevent progression of palsy and placement of a nerve graft if clinically indicated. A 28-year-old woman presented with a 2-year history of progressive painless right peroneal nerve palsy.[ncbi.nlm.nih.gov]
Resection and nerve graft reconstruction were performed to prevent progression of motor compromise and to allow recovery of motor function. An algorithm for the management of focal intraneural tumors is shown.[ncbi.nlm.nih.gov]
The process appears to be progressive; and when detected in a small nerve, excision is recommended to prevent proximal extension and possible development of motor or sensory deficits.[ncbi.nlm.nih.gov]