Presentation
Six cases of severe histamine mediated reactions are presented and detailed analyses of the drugs in these and other reported reactions is made showing varied clinical patterns with different drugs. [ncbi.nlm.nih.gov]
Berger T, Kassirer M, Aran AA (2014)Injectional anthrax - New presentation of an old disease. Eurosurveillance 19. [acmicrob.com]
Entire Body System
- Intravenous Drugs
RESULTS: Seventy-four percent of the females disclosed that they used intravenous drugs, and 88% knew that their male partners were intravenous drug users. [ncbi.nlm.nih.gov]
[…] the quality of the preparation and administration of intravenous drugs. [link.springer.com]
— intravenously adverb Examples from the Corpus intravenous • Conclusions - Seroconversion to HIV-1 among intravenous drug misusers is associated with bacterial pneumonia. • Today, some research suggests that 50 percent of the city's intravenous drug [ldoceonline.com]
- Falling
After falling significantly since the peak of the epidemic, HIV rates in the United States have been leveling out, but pockets of infection persist, especially in high-risk groups such as young people and men who have sex with men. [reuters.com]
[…] and fall injuries and delirium [ 2 ]. [link.springer.com]
[…] a minute Respiratory rate higher than 20 breaths a minute Severe Sepsis Within this state, a person must have one or more of the following symptoms: Improperly working heart Respiratory (breathing) struggles Pain in the abdomen Platelet count begins falling [drugrehab.org]
The more active and fit you are as you age, the less likely you are to fall and break a bone. Good nutrition. Eat a healthy diet and make certain that you're getting enough calcium and vitamin D. Quit smoking. Smoking cigarettes speeds up bone loss. [mayoclinic.org]
Individuals who fall into both categories are particularly vulnerable to HIV. [avert.org]
- Rigor
The effectiveness of needle exchange programs in reducing HIV incidence is not definitely known because of the difficulty associated with conducting rigorous evaluations. [hivinsite.ucsf.edu]
Gastrointestinal
- Nausea
[…] intravenous anti-nausea drug. [medicare.gov]
[…] for about an hour, there is a sedation effect complete with the effects of: Relaxation Drowsiness Lack of pain (analgesia) Euphoria Reduced Anxiety Increased empathy for others Potential risks from injecting heroin include: Liver damage Rotting teeth Nausea [treatment4addiction.com]
In people with diabetes, infectious intertrigo may result in cellulitis, a potentially serious infection that can cause red streaks, fever, nausea, and vomiting. [verywellhealth.com]
For instance, they may be used during a short hospital stay to administer medication during surgery or to give pain medications, nausea medications, or antibiotics. A standard IV line can typically be used for up to four days. [healthline.com]
Symptoms of hepatitis C include: Fever Fatigue Poor appetite Nausea/vomiting Stomach pain Joint or muscle pain Abnormal urine or bowel movements Jaundice Mortality rates from chronic HCV have been on the rise, and in 2007 surpassed those of HIV infections [americanaddictioncenters.org]
- Vomiting
Relaxation Drowsiness Lack of pain (analgesia) Euphoria Reduced Anxiety Increased empathy for others Potential risks from injecting heroin include: Liver damage Rotting teeth Nausea Slowed reaction times Heroin withdrawal effects inclue: Diarrhea Convulsions Vomiting [treatment4addiction.com]
In people with diabetes, infectious intertrigo may result in cellulitis, a potentially serious infection that can cause red streaks, fever, nausea, and vomiting. [verywellhealth.com]
Symptoms of hepatitis C include: Fever Fatigue Poor appetite Nausea/vomiting Stomach pain Joint or muscle pain Abnormal urine or bowel movements Jaundice Mortality rates from chronic HCV have been on the rise, and in 2007 surpassed those of HIV infections [americanaddictioncenters.org]
Overdose symptoms will vary depending on the type and amount of drug taken, but generally include the following: Nausea and/or vomiting Drowsiness Diarrhea Difference in pupil size or reactivity Tremors or convulsions Trouble breathing Irregular heart [dualdiagnosis.org]
[…] brain is disrupted that results in a weakness of certain part of the body such as an arm, leg, or face Formation of septic emboli within the bloodstream (septic emboli are blood clots admixed with bacteria) Abdominal signs and symptoms such as nausea/vomiting [dovemed.com]
- Diarrhea
[…] effects of: Relaxation Drowsiness Lack of pain (analgesia) Euphoria Reduced Anxiety Increased empathy for others Potential risks from injecting heroin include: Liver damage Rotting teeth Nausea Slowed reaction times Heroin withdrawal effects inclue: Diarrhea [treatment4addiction.com]
Overdose symptoms will vary depending on the type and amount of drug taken, but generally include the following: Nausea and/or vomiting Drowsiness Diarrhea Difference in pupil size or reactivity Tremors or convulsions Trouble breathing Irregular heart [dualdiagnosis.org]
Musculoskeletal
- Osteoporosis
Osteoporosis treatment: Medications can help Osteoporosis treatment may involve medication along with lifestyle change. Get answers to some of the most common questions about osteoporosis treatment. [mayoclinic.org]
Injectable osteoporosis drugs: Medicare helps pay for an injectable drug if you’re a woman with osteoporosis who meets the criteria for the Medicare home health benefit and has a bone fracture that a doctor certifies was related to post-menopausal osteoporosis [medicare.gov]
Psychiatrical
- Euphoria
After the rush, for about an hour, there is a sedation effect complete with the effects of: Relaxation Drowsiness Lack of pain (analgesia) Euphoria Reduced Anxiety Increased empathy for others Potential risks from injecting heroin include: Liver damage [treatment4addiction.com]
The needle is associated with blissful feelings, euphoria, relaxation and excitement. These feelings are very tempting and addictive. Law enforcement efforts are another reason that individuals may begin to inject drugs. [alcoholrehab.com]
Injecting drugs is one of the fastest ways to get the substance to the brain, creating an intense euphoria commonly referred to as a “rush.” [americanaddictioncenters.org]
Neurologic
- Confusion
The difficulties in diagnosing such reactions and in determining the drug responsible and how these difficulties have led to confusion in the literature are discussed. [ncbi.nlm.nih.gov]
Do Not Confuse With information is added at the top of each applicable monograph to enhance medication safety. Reorganized drug side effects reflect the latest information on frequency, seriousness, and other important considerations. [skyscape.com]
The condition is often confused with contact dermatitis, psoriasis vulgaris inversa, and Hailey-Hailey disease, thus correct diagnosis is important. [mdmag.com]
Use only one model of pump to avoid confusion and programming errors. [ihi.org]
It may lead to depression, memory loss, confusion, irritability, hostility, paranoia, increased risk-taking behavior, impulsivity, aggression, inability to feel pleasure, emotional numbness, hallucinations, and impaired cognition and judgment. [dualdiagnosis.org]
Treatment
Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. [webmd.com]
Then the high cost of treatment has to be weighed against the possible outcomes of a lack of treatment. [americanaddictioncenters.org]
The prevention, treatment, and follow-up of severe histamine mediated reactions are considered. [ncbi.nlm.nih.gov]
Osteoporosis treatment: Medications can help Osteoporosis treatment may involve medication along with lifestyle change. Get answers to some of the most common questions about osteoporosis treatment. [mayoclinic.org]
Successful treatment is not the same for everyone and evidence-based treatment plans take personal preferences as well as scientific research and clinical expertise into account. [dualdiagnosis.org]
Prognosis
Surgery may be required in some cases Untreated Intravenous Drug Abuse Endocarditis can lead to an extremely poor prognosis and is almost always be fatal. With appropriate early diagnosis and treatment, the outcomes are better. [dovemed.com]
Prognosis The prognosis is positive for the majority of patients. The underlying risk factors should be addressed to diminish the intertrigo outbreaks. [ncbi.nlm.nih.gov]
Aspects on epidemiology, clinical and laboratory findings and prognosis. Scan J Infect Dis 1983; 41(suppl): 49-58. Baddour LM: Twelve year review of recurrent native valve infective endocarditis. A disease of the modern antibiotic era. [medigraphic.com]
Etiology
[Etiology of intertrigo in adults: A prospective study of 103 cases]. J Mycol Med. 2017 Mar;27(1):28-32. [PubMed: 27554869] 8. Kalkan G, Duygu F, Bas Y. [ncbi.nlm.nih.gov]
Etiology of intertrigo Intertrigo develops from mechanical factors and secondary infection. Heat and maceration are central to the process. Opposing skin surfaces rub against each other, at times causing erosions that become inflamed. [emedicine.medscape.com]
(Etiology) In most cases, Intravenous Drug Abuse Endocarditis is caused by bacteria that include the following: Staphylococcus aureus, which is the most common infection agent Streptococcus sp. Enterococcus sp. [dovemed.com]
Ndiaye M, Taleb M, Diatta BA, Diop A, Diallo M, Diadie S, Seck NB, Diallo S, Ndiaye MT, Niang SO et al: [etiology of intertrigo in adults: a prospective study of 103 cases]. Journal de mycologie medicale 2017, 27(1):28–32. 7. [bmcgeriatr.biomedcentral.com]
Epidemiology
Author information 1 National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT. Abstract Residual HIV-infected blood in needles and syringes is a source of HIV infection. [ncbi.nlm.nih.gov]
Página 45 - A mathematical model of a heroin epidemic: implications for control policies", Journal of Epidemiology and Community Health, vol. 33, 1979, pp. 299-304. 6. [books.google.es]
Lange M, Salaki JS, Middleton JR: Infective endocarditis in heroin addicts: epidemiological observations and some unusual cases. Am Heart J 1978; 96: 144-152. [medigraphic.com]
Div of Field Svcs, Epidemiology Program Office, CDC. Editorial Note Editorial Note: Fungal endophthalmitis is a recognized complication of IV-drug use (1). Infection results from hematogenous spread after nonsterile injection (2). [cdc.gov]
Pathophysiology
Pathophysiology Environmental factors and genetic causes play a leading role in the development of intertrigo. One of these factors is the friction caused by adjacent skin surfaces causing inflammation of the epidermis. [ncbi.nlm.nih.gov]
Pathophysiology When injecting a drug intravenously, the individual introduces a bolus of the drug into the vein, producing a rapid and powerful drug high. [emedicine.medscape.com]
The drug pK a is constant, but the normal urinary pH may vary from 4.5 to 8.0, depending on diet, pathophysiology, and drug intake. The undissociated drug is easily reabsorbed from the renal tubule back to the body. [intechopen.com]
Prevention
Amy Lansky, deputy director in the Division of HIV/AIDS Prevention at CDC, said the findings will be used as CDC focuses on prevention efforts on high-risk populations. [reuters.com]
Prevention models studied Of the prevention programs simulated in the model, the authors found that opioid agonist therapy, or OAT, was the most cost-effective. [sciencedaily.com]
The prevention, treatment, and follow-up of severe histamine mediated reactions are considered. [ncbi.nlm.nih.gov]
1 1.2 Million Hospitalizations are impacted by preventable adverse drug errors associated with injectable medications. 2 [baxter.com]