Presentation
A 65-year-old woman presented to our rheumatology clinic with pain and swelling of multiple joints of her hands. After a thorough evaluation, she was diagnosed with rheumatoid arthritis and was started on hydroxychloroquine therapy. [ncbi.nlm.nih.gov]
Genital psoriasis can be included in these presentations although it is not exactly an inverse form: it presents with well-defined, erythematous, desquamating plaques ( Figure 12 ). [clinicaldermatology.eu]
Alerts and Notices Synopsis Inverse psoriasis, also known as intertriginous or flexural psoriasis, is a form of psoriasis that presents in skin folds such as the inframammary areas, the axillae, and the inguinal folds. [visualdx.com]
Immune System
- Splenomegaly
If you are already a member, please log in here: Username or E-mail Password Remember Me Forgot Password New Case Studies Splenomegaly and Psoriasis—A Case Report September 10, 2018 You must be a Wellspring community member to view this content. [wellspring.digital]
Skin
- Eruptions
Another possibility in the differential diagnosis is chronic pityriasis lichenoides, a disease that can be eruptive at onset, while desquamation is really very limited. Finally, there is secondary syphilis. [clinicaldermatology.eu]
Reports showed that 13% of children with psoriasis had psoriatic napkin eruptions with dissemination, whereas 4% had a localized psoriatic napkin eruption [ 32 ], with anogenital psoriasis occurring four-times more often in children over 2 years old than [ncbi.nlm.nih.gov]
[…] is also a risk factor for cardiovascular disease. 3 As emerging research illustrates its increasing complexity, psoriasis is now considered a systemic inflammatory disorder. 2 Clinically, there are 5 types of psoriasis: plaque psoriasis, guttate or eruptive [clinicaladvisor.com]
It is recommended only for chronic or inactive psoriasis, not for acute or inflamed eruptions. People with kidney problems should use anthralin with caution. [pennstatehershey.adam.com]
Seborrheic dermatitis of the folds appears as an erythematous eruption, often with erosions and fissures. [dovepress.com]
- Skin Rash
Other treatments may be necessary if your skin becomes infected. It can be difficult to self-diagnose a skin rash. If you develop an unexplained rash that won’t go away or is getting worse, you should see your doctor. [healthline.com]
Urogenital
- Genital Lesions
Diagnosis is based on clinical background, symptoms, clinical signs, and the appearance of skin lesions in the genital area or elsewhere in the body [ 19, 23, 33, 34 ]. [ncbi.nlm.nih.gov]
In particular, a patient with psoriatic arthritis and a significant involvement of genitalia and intergluteal folds experienced an almost complete regression of the genital lesions after 90 days of treatment with adalimumab.50 In another patient with [dovepress.com]
- Pruritus Vulvae
Pruritus vulvae. Curr Obstet Gynaecol. 2002; 12 :231–234. doi: 10.1054/cuog.2001.0265. [ CrossRef ] [ Google Scholar ] 39. Camilleri MJ, Calobrisi SD. Skin eruptions in the diaper area. [ncbi.nlm.nih.gov]
- Penile Lesion
Non-oncological and non-infectious diseases of the penis (penile lesions) EAU-EBU Update Ser. 2006; 41 :13–19. doi: 10.1016/j.eeus.2005.11.004. [ CrossRef ] [ Google Scholar ] 35. MacLean AB, Roberts DT, Reid WMN. [ncbi.nlm.nih.gov]
Treatment
Treatments are well tolerated with minimal side effects. [ncbi.nlm.nih.gov]
Conventional topical and systemic treatments can be limited in terms of efficacy, acceptability and safety. The 308 nm excimer laser has been shown to be effective in the treatment of psoriatic plaques. [journals.lww.com]
If necessary, your doctor may prescribe antibiotic or antifungal treatments. Other treatments may be necessary if your skin becomes infected. It can be difficult to self-diagnose a skin rash. [healthline.com]
Prognosis
Posted : April 10, 2012 Last Update Posted : November 18, 2014 Sponsor: Collaborator: Information provided by (Responsible Party): Tecno Sun SRL Brief Summary: The purpose of this study is to evaluate the efficacy of Aerosal® compared to placebo in the prognosis [clinicaltrials.gov]
In all these cases, it is recommended to perform a biopsy since a delay in diagnosis may compromise prognosis. [clinicaldermatology.eu]
Etiology
The exact etiology and pathogenesis is unknown but immunologic, genetic, and environmental factors are all are implicated in the development of the disease. [dermatologyadvisor.com]
The etiology of inverse and genital psoriasis is still unknown and further studies are needed in order to clarify these diseases [ 1 ]. [ncbi.nlm.nih.gov]
Introduction Psoriasis is a complex, chronic inflammatory skin condition that is common in individuals of European descent, affecting 1%–3% of the population. 1 The disease has a multifactorial etiology; environmental influences, such as infection or [dovepress.com]
Epidemiology
We review current evidence and establish whether inverse psoriasis is a separate disease entity based on characteristics in terms of epidemiology, pathogenesis, clinical and histologic presentation, microbiology, and treatment. [ncbi.nlm.nih.gov]
Epidemiology Bimodal peaks Young adulthood (ages 16 to 22 years old) Older age (late 50s) Prevalence : 1-2% of general population (U.S.) Men and women affected equally III. [fpnotebook.com]
Pathophysiology
We highlight the role of dopamine in the pathophysiology of this dermatosis. [ncbi.nlm.nih.gov]
Roles of calcitonin gene-related peptide in the skin, and other physiological and pathophysiological functions. Kim YJ, Granstein RD. Kim YJ, et al. [pubmed.ncbi.nlm.nih.gov]
Pathophysiology Underlying genetic predisposition is common (30% with Psoriasis also have a first degree relative with Psoriasis) Pathogenesis is likely a combination between genetic predisposition and exposure to inciting triggers Autoimmune Viral infection [fpnotebook.com]
These Th17 cells pathway are critically important in the pathophysiology of psoriasis. [dermatologyadvisor.com]
Prevention
From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world. The Merck Manual was first published in 1899 as a service to the community. [merckmanuals.com]
Using your current browser will prevent you from accessing features on our website. An update is required. [trinityhealth.org]
To prevent irritation, wear loose-fitting, absorbent clothes. That will make it easier for your skin to breathe. Inverse psoriasis treatment Inverse psoriasis can be difficult to treat. Your doctor may prescribe topical ointments or steroids. [healthline.com]
Transplantation Substance Use and Addiction Surgery Surgical Innovation Surgical Pearls Teachable Moment Technology and Finance The Rational Clinical Examination Tobacco and e-Cigarettes Toxicology Trauma and Injury Treatment Adherence United States Preventive [jamanetwork.com]