Presentation
Spinal cord lesions producing motor and sensory disturbances were present in one. Late psychiatric disorders were observed in both patients. [ncbi.nlm.nih.gov]
Here, we present the case of a 50-year-old man who presented signs of as a stroke mimic. In addition, we briefly discuss the various known causes of stroke mimics. [jmedicalcasereports.biomedcentral.com]
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Clinical presentation. The manifestations of acute iodine ingestion are related largely to the corrosive effect on mucous membranes and the GI tract. [mhmedical.com]
These patients presented with thyroid conditions ranging from subclinical hyperthyroidism to florid thyrotoxicosis. [mja.com.au]
Entire Body System
- Fever
They are especially used in— Acute Catarrh and Hay Fever ,—Potassium Iodide with Arsenic internally; also Iodine and Carbolic Acid in weak solution locally. [henriettes-herb.com]
Abdominal pain Coma Delirium Fever Lack of urine output Seizure Shock Shortness of breath Stupor Swelling of face and body Weak pulse Side Effects of Iodine Poisoning A patient with an overdose of iodine shows symptoms that are similar to iodine deficiency [tandurust.com]
Symptoms include burning mouth and stomach, fever, diarrhea and, in severe cases, coma [1]. Chronic iodine toxicity. [nutrientsreview.com]
Severe Symptoms of Iodine Overdose If the overdose continues it can lead to: Abdominal pain Delirium Fever Lack of urine output Seizures Shock Swelling of face and body Shortness of breath Stupor Weak pulse Coma Japanese Kelp Consumption A type of acne [iodine-resource.com]
Furthermore, there may be fever while some develop delirium. It is frequent for a casualty to report pain in the throat and mouth and metallic taste in the mouth. [ic.steadyhealth.com]
- Falling
You can get whiplash from: A sports injury A fall Being punched or shaken Whiplash can take days, weeks, or even months to develop. You may think that you're all right after a car accident, fall, or other initial injury. [spinoteka.hr]
Often batteries will only be able to withstand 500 - 1000 charge discharge cycles before their capacity falls. [electronics-notes.com]
Research ArticleArticle Journal of Pharmacology and Experimental Therapeutics May 1969, 167 (1) 159-165; Abstract The imidazoline derivatoves naphazoline and tetrahydrozoline produce a fall in body temperature when injected systemically into the rat. [jpet.aspetjournals.org]
Right now, there's no need for panic, because radiation levels are currently falling at Fukushima, where workers are finally getting the plant under control. [businessinsider.com]
It is thought that the fall of melatonin levels acts like a biological clock and triggers the onset of puberty. In her gerbil study she found that the high fluoride treated animals were reaching puberty earlier than the low fluoride ones. [drsircus.com]
- Fatigue
And, without the thyroid hormones to keep your metabolism up, we see a cascade of symptoms, including a slowed metabolic rate, fatigue and weight gain. [study.com]
Hypothyroidism generally strikes women, causing fatigue, weight gain, and cancers amongst many other problems. [healthwyze.org]
I worried about how I would feel (even more fatigued) and if I would develop severely low blood pressure or possibly have a heart attack if this compensatory response were prevented. [fluoroquinolonethyroid.com]
Low thyroid hormone levels (hypothyroidism) in older children and adults cause goiter, fatigue, impaired mental function, low body temperature with cold intolerance, weight gain and constipation. [nutrientsreview.com]
Chronic fatigue 5. EPS : dystonia 6. Resting tremor, bradykinesia 7. Rigidity of face Parkinson-like 8. Postural instability Non responsive to levodopa 30. Diagnosis and Management 31. [slideshare.net]
- Myxedema
Myxedema is a condition where the individual has dry skin and develops inflammation around the lips and nose. Severe effect is mental retardation. An overdose is the cause of thyroid papillary cancer. [tandurust.com]
Thus, iodine toxicity can eventually cause iodide goiter, hypothyroidism, or myxedema. Very large amounts of iodide may cause a brassy taste in the mouth, increased salivation, GI irritation, and acneiform skin lesions. [merckmanuals.com]
Amiodarone Induced Hypothyroidism are similar to hypothyroidism symptoms in general: fatigue, lethargy, cold intolerance, mental sluggishness, weakness, constipation, heavy or abnormal periods for women, dry skin, eyes and hair, goiter, and in extreme cases, myxedema [fluoroquinolonethyroid.com]
- Short Stature
Severe maternal iodine deficiency retards fetal growth and brain development, sometimes resulting in birth defects, and, in infants, causes cretinism, which may include intellectual disability, deaf-mutism, difficulty walking, short stature, and sometimes [merckmanuals.com]
Iodine deficiency in infants (or fetuses due to iodine deficiency in their mothers) may result in cretinism with impaired brain development and permanent mental retardation, short stature, deafness and other birth defects [1]. [nutrientsreview.com]
Respiratoric
- Pneumonia
Catarrhal Pneumonia ,—the Ammonium Iodide, to prevent caseation of the products. Arsenic may well be combined with it. [henriettes-herb.com]
[…] pralidoxime with each regimen. 2 Patients who received the high-dose regimen had lower mortality (1% vs 8%) and less intubation and ventilator support, developed less muscle weakness, and required less atropine during the first day, and fewer developed pneumonia [ncbi.nlm.nih.gov]
* The Hazards of Gastric Lavage for Intentional Self Poisoning in a Resource Poor Location Clin Tox 2007;45(2):136-43 Not beneficial, rather increases chances of Aspiration Pneumonia & Deaths* 56. [slideshare.net]
Headache, dizziness, delirium, collapse and stupor, death due to circulatory collapse, asphyxia from oedema of glottis, aspiration pneumonia or pulmonary oedema has been reported. [inchem.org]
Secondary Bacterial Pneumonia by Staphylococcus aureus Following Influenza A Infection Is SaeR/S Dependent. The Journal of Infectious Diseases. (2018). Guerra, F. E., et al. [jove.com]
Gastrointestinal
- Vomiting
Easily Tolerated Foods After Vomiting Here is my list of easily tolerated foods to introduce gradually after a bout of gastroenteritis, food poisoning, or any other vomiting bug. [listentoyourgut.com]
This condition is marked by brown stains on the lips and mouth; burning pain in the mouth, throat, and stomach; vomiting (blue vomit if the stomach contained starches, otherwise yellow vomit); bloody diarrhea. [medical-dictionary.thefreedictionary.com]
Apply this treatment only when the victim is alert but discontinue treatment when victim is vomiting or having convulsions. Activated charcoal is effective in decontaminating the stomach. [tandurust.com]
It's for that reason that warnings always say not to induce vomiting if ingested (unless otherwise advised by poison control). [globalhealingcenter.com]
Initial Symptoms Initial symptoms of iodine toxicity may be: Skin rash Burning mouth and throat Sore teeth and gums Head cold symptoms Vomiting Stomach upset and diarrhea These symptoms may be confused with an iodine allergy or iodine allergy symptoms [iodine-resource.com]
- Diarrhea
Symptoms include burning pain in the mouth and esophagus, abdominal pain, vomiting, diarrhea, delirium, shock, nephritis, laryngeal edema, and circulatory collapse. [medical-dictionary.thefreedictionary.com]
Keep in mind it usually takes at least 12 hours of severe vomiting and diarrhea to make a child or adult significantly dehydrated. [listentoyourgut.com]
Acute iodine toxicity may cause symptoms such as diarrhea, nausea and vomiting, as well as a burning sensation in the stomach, throat and mouth. Weak pulse and coma are also potential complications of acute toxicity. [livestrong.com]
Signs of Iodine Toxicity Harmless amount of iodine contained in medicine results in these initial symptoms: Burning mouth and throat Head cold symptoms Skin rash Sore throat and gums Stomach upset Diarrhea Vomiting Toxicity from iodine is a risk as it [tandurust.com]
Symptoms include burning mouth and stomach, fever, diarrhea and, in severe cases, coma [1]. Chronic iodine toxicity. [nutrientsreview.com]
- Food Poisoning
What Is Food Poisoning * Food poisoning doesn't actually mean you were poisoned, it simply means there were some bad bacteria, viruses or parasites in the food you ate. [listentoyourgut.com]
DMSO helps absorption; Food poisoning 6 drops, 3-4 x daily –for 3 days Brings relief for food poisoning very quickly –usually within a couple of hours; E.g. [healyourselfathome.com]
Reference: in Wiesen, high Ru Qin, Jin Xiaomei editor, common chemical food poisoning rapid disposal technologies. Uses 1. [chemicalbook.com]
Skin
- Ulcer
Iodoform and Iodol are highly esteemed as internal remedies in— Chronic Gastric Catarrh, and intestinal catarrh, ulceration of the gastrointestinal mucous membrane, etc., —Iodol given midway between meals. [henriettes-herb.com]
Contact with eyes causes ulceration of conjunctiv a and cornea. Contact with skin causes irritation and possible dermatitis; systemic poisoning can occur by absorption through skin. [cameochemicals.noaa.gov]
Ovarian Cyst Dose similar to FDB Precancerous skin lesions/ leg ulcers Rub in twice daily Regenerates skin from bottom up, eventually sloughing off old skin with little/no scar formation; adding vitamin E helps too; Radioactive Fallout SSKI Dose Adult [healyourselfathome.com]
Case 3 Two patients with leg ulcers got worse after the application of a compound mixture of sugar and povidone iodine (sugar/PI compound). [inchem.org]
- Blister
Tincture of Iodine may cause rash, blistering or crusting on the skin. MEDICAL APPLICATIONS: Iodine poisoning may happen if you have been exposed to high doses of radiographic contact dyes or a drug called amiodarone. [iodine-resource.com]
Skin contact with toxins can cause various acute cutaneous symptoms (eg, rashes, pain, blistering); chronic exposure may cause dermatitis. [msdmanuals.com]
- Formication
[…] acid which is toxic to the optic nerve early toxicity of formic acid is metabolic acidosis by formic acid itself formic acid also binds to cytochrome oxidase blocking oxidative phosphorylation resulting in lactic acidosis which is the latter and leading [medbullets.com]
[…] solution UN 3407 5.1 Chlorate and magnesium chloride mixture solution UN 3408 5.1 Lead perchlorate solution UN 3409 6.1 Chloronitrobenzenes, liquid UN 3410 6.1 4-Chloro-o-toluidine hydrochloride solution UN 3411 6.1 beta-Naphthylamine solution UN 3412 8 Formic [en.wikipedia.org]
Neurologic
- Burning Sensation
Acute iodine toxicity may cause symptoms such as diarrhea, nausea and vomiting, as well as a burning sensation in the stomach, throat and mouth. Weak pulse and coma are also potential complications of acute toxicity. [livestrong.com]
It is when a person has taken too much iodine that his body begins to show symptoms of discomfort such as vomiting, nausea, diarrhea, burning sensations around the upper gastrointestinal tract, weak pulse, and – god forbid – coma. [cheers4health.com]
Workup
Routine blood workup reveals normal serum electrolytes with a raised amylase level of 300. Diagnosis ??? ?? 2. Organophosphorus Poisoning Presenters : Dr Lohit Chauhan : Dr Dhananjay Gupta Moderator : Dr. Gurmeet Kaur 3. [slideshare.net]
Treatment
[…] technologies for each contaminant Critical concepts of water quality control as applied in water treatment in conventional or chemical treatment plants Disinfection and fluoridation requirements Common problems with water distribution systems, including [books.google.com]
[…] for this food FSC 1.5.3 9/10/2018 Chutney South Africa Irradiated chillies Irradiated – not a permitted treatment for this food FSC 1.5.3 9/10/2018 Chutney South Africa Irradiated onion Irradiated – not a permitted treatment for this food FSC 1.5.3 9 [vietnamtradeoffice.net]
Other indications include treatment of hyperthyroidism, radiation protectant of the thyroid gland, pre-operative preparation of patients with Graves disease and the treatment of some dermatological conditions such as cutaneous lymphatic sporotrichosis [dermnetnz.org]
Apply this treatment only when the victim is alert but discontinue treatment when victim is vomiting or having convulsions. Activated charcoal is effective in decontaminating the stomach. [tandurust.com]
Treatment includes activated charcoal, breathing support (if necessary), fluids and milk and medications which deal with accompanying symptoms. [ic.steadyhealth.com]
Prognosis
Please find relevant information on First Aid for Iodide (I−) Poisoning regarding cause, signs & symptoms, administration of first aid treatment, prognosis, preventive measures, and additional resources HERE. [dovemed.com]
INGESTION: alimentary absorption is very rapid; action during first10-15 min. determines prognosis. Give egg whites, milk, or activated charcoal and induce vomiting; consult physician. EYES: flush with water for at least 15 min. [cameochemicals.noaa.gov]
QTc prolongation • Indicates poor prognosis in OP- poisoning 1. Cholinergic stimulation of heart : M2 a. negative ionotropy b. negative chronotropy 2. Oxidative stress causes conduction problems * Shadnia S, Okazi A, et al. [slideshare.net]
9.1.1 Ingestion 9.1.2 Inhalation 9.1.3 Skin exposure 9.1.4 Eye contact 9.1.5 Parenteral exposure 9.1.6 Other 9.2 Chronic poisoning 9.2.1 Ingestion 9.2.2 Inhalation 9.2.3 Skin exposure 9.2.4 Eye contact 9.2.5 Parenteral exposure 9.2.6 Other 9.3 Course, prognosis [inchem.org]
Epidemiology
Scientific American spoke with John Boice, a professor at Vanderbilt University's Vanderbilt-Ingram Cancer Center and a cancer epidemiologist with the International Epidemiology Institute in Rockville, Md., to better understand why potassium iodide is [scientificamerican.com]
Journal of Exposure Science & Environmental Epidemiology 2011, 21 (4), 395-407. DOI: 10.1038/jes.2010.31. Kathleen L. Caldwell, Amir Makhmudov, Elizabeth Ely, Robert L. Jones, Richard Y. Wang. Iodine Status of the U.S. [pubs.acs.org]
Clinico-Epidemiological Characteristics of Patients Presenting with Organophosphorus Poisoning. N Am J Med Sc. Vol 4(3), JMarch 2012 14. 5. Relative human Toxicity Eddleston M et al. [slideshare.net]
Overlapping perchlorate epidemiologic research at Texas Tech University is also supported by the State of Texas Advanced Research Program (3644-0007-2006) and by the Gerber Foundation. References Almström P 2006. [ehp.niehs.nih.gov]
Infection Control & Hospital Epidemiology, 10 (10): 447-450. Gommolin IH (1987) Iodated glycerol-induced hypothyroidism. Drug Intell Clin Pharm, 21 : 726-727. [inchem.org]
Pathophysiology
"Pathophysiology: The biological basis for disease in Adults and Children". 5th Edition. [marefa.org]
Published on Jan 17, 2016 Pathophysiology and Approach and Management of a case of OP poisoning 1. Clinical Vignette You are posted as a CMO, casualty in the month of June. [slideshare.net]
A better understanding of the pathophysiology of pesticides might stop doctors using inappropriate antidotes. There may also be considerable benefit from the development of postgraduate training programmes in clinical toxicology. [ncbi.nlm.nih.gov]
"Pathophysiology: The biological basis for disease in Adults and Children". 5th Edition. Elsievier Publishing [ page needed ] ^ March 23, 2011. "POTASSIUM IODIDE - ORAL (SSKI) side effects, medical uses, and drug interactions". Medicinenet.com. [en.wikipedia.org]
Prevention
They don’t prevent your body from taking in the radiation and don’t help prevent radiation damage to other parts of the body. Potassium iodide is available without a prescription as pills or drops. It is also found in radiation exposure kits. [blogs.webmd.com]
[…] contamination of drinking water requires a multidisciplinary perspective, one that incorporates elements of bacteriology, chemistry, physics, engineering, public health, preventive medicine, and control and evaluation management. [books.google.com]
Apply vitamin E oil(E.g. from capsule) to keep area moist day and night and prevent reddened, dry skin from flaking. [healyourselfathome.com]
This effect is useful when we want to prevent unwanted reactions. [www2.uni-siegen.de]
To help prevent this kind of toxicity, the Institute of Medicine provided the guideline known as Tolerable Upper Intake Levels (TUL). [tandurust.com]