Presentation
There, before initiation of the program, a goiter endemic of moderate severity was present, as evidenced by goiter prevalence of 55% in school children. [ncbi.nlm.nih.gov]
In the present study, three talukas were observed of not using noniodized salt (Lalpur, Jodiya, Dhrol). [thetrp.net]
N Engl J Med 1997;337:888-896. 468 ページ - Role of aberrant HLA-DR expression and antigen presentation in induction of endocrine autoimmunity. Lancet 1983; 2: 1115-19. 401 ページ - F, et al. [books.google.com]
TSH 4.10micromole per litre, fT3 5.4picomole per litre, fT4 Case 2 A 17-year-old female presented with weight gain and tiredness. She was found to have a small central goitre. [endocrine-abstracts.org]
But if aminotriazole was present in a sufficiently low dose to cause no thyroid stimulation to occur, no harm could result since it is not a carcinogen on contact. [frantzmd.info]
Entire Body System
- Goiter
By April 1983, overall goiter frequency in school children had declined to 6.1%, and large goiters (WHO Grade 2) had virtually disappeared. [ncbi.nlm.nih.gov]
E01.2 iodine-deficiency (endemic) E01.2 Struma - see also Goiter nodosa (simplex) E04.9 ICD-10-CM Diagnosis Code E04.9 Nontoxic goiter, unspecified 2016 2017 2018 2019 Billable/Specific Code Applicable To Goiter NOS Nodular goiter (nontoxic) NOS endemic [icd10data.com]
Apparently, this was a case of endemic goiter. Endemic goiter used to be common in the United States. Indeed, the upper Midwest was once known as the “goiter belt” in reference to the prevalence of goiter only a few generations ago. [healio.com]
Two urban areas were selected from the moderate endemic zones of goiter. [journals.lww.com]
- Euthyroid
This disorder is entirely preventable by making sure that pregnant women have sufficient iodine in their diet to be euthyroid (having adequate thyroid hormone levels). [courses.washington.edu]
A gioter is an enlarged thyroid gland and can be caused by hypothyroidism. hyperthyroidism, or euthyroid. In your case above hyperthyroidism was the cause of the goiter, hyperthyroidism is not caused by iodine defiency. [allnurses.com]
Precise control of how many proteins are made from these genetic blueprints maintains the normal or euthyroid thyroid state. [endocrine.surgery.ucsf.edu]
Thyroid iodine content and turnover in euthyroid subjects: validity of estimation of thyroid iodine accumulation from short-term clearance studies. J. Clin. Endocrinol. Metab. 29, 721–727 (1969). 14. Stanbury, J. B. et al. [nature.com]
Euthyroid pubertal goiter is especially frequent in adolescents, because iodine metabolism is accelerated during this period of life ( Delange & Ermans, 1967 ). [intechopen.com]
- Myxedema
Myxedema is a rare but life-threatening complication of hypothyroidism that can be caused by iodine deficiency. [healthline.com]
On occasions, the “escape” or “adaptation” phenomenon does not occur, giving rise to the persistent inhibition of thyroid hormone formation, leading to hypothyroidism and goiter (myxedema). [omicsonline.org]
Respiratoric
- Hoarseness
But large goiters can make it hard to breathe or swallow and can cause a cough and hoarseness. [mayoclinic.org]
This can lead to symptoms including a visible swelling at the base of the neck, coughing, difficulty swallowing, tight feeling in the throat, hoarseness or trouble breathing. [livestrong.com]
Symptoms may include fatigue, weight gain, hair loss, dry hair, dry skin, constipation, cold intolerance, a puffy face, hoarseness, muscle weakness/aches, depression, memory loss, and more. [prevention.com]
Symptoms expressing themselves later in the course of the disease are hoarseness; menstrual disorders; puffy hands, face, and feet; thickening of the skin; thinning of eyebrows; increased cholesterol levels; muscle and/or joint aches and stiffness; slowed [clinicaladvisor.com]
When symptoms do occur, the following are most common: throat symptoms of tightness, cough, and hoarseness trouble swallowing in severe cases, difficulty breathing, possibly with a high-pitch sound Other symptoms may be present because of the underlying [medicalnewstoday.com]
- Cough
But large goiters can make it hard to breathe or swallow and can cause a cough and hoarseness. [mayoclinic.org]
Surgery to remove an enlarged thyroid can relieve compression of nearby structures and improve symptoms in patients with related difficulty swallowing, cough, or shortness of breath. [endocrine.surgery.ucsf.edu]
This can lead to symptoms including a visible swelling at the base of the neck, coughing, difficulty swallowing, tight feeling in the throat, hoarseness or trouble breathing. [livestrong.com]
When symptoms do occur, the following are most common: throat symptoms of tightness, cough, and hoarseness trouble swallowing in severe cases, difficulty breathing, possibly with a high-pitch sound Other symptoms may be present because of the underlying [medicalnewstoday.com]
Iodine deficiency is also linked to the development of goiter (thyroid enlargement), the condition of which can cause coughing, rapid heart rate, heat intolerance, shortness of breath, throat tightness, and weight gain. [verywell.com]
Gastrointestinal
- Choking
[…] elevated blood cholesterol levels pain or stiffness in the muscles and joints slowed heart rate thinning hair depression poor memory a heavier-than-normal period in menstruating women In infants, hypothyroidism is likely to cause symptoms like: frequent choking [healthline.com]
If you have a goiter, you may experience a choking sensation or have difficulty swallowing or breathing. [prevention.com]
Patients with a large goiter may experience symptoms of choking, especially when lying down, and difficulty swallowing and breathing. [thyroid.org]
Neurologic
- Cognitive Impairment
Complications may include: heart disease and related disorders, such as an enlarged heart and heart failure mental health issues such as depression and cognitive impairment damage to the body’s peripheral nerves, known as peripheral neuropathy impaired [healthline.com]
- Headache
[…] fertility rate, increased infant mortality, fibrocystic breast disease, atherosclerosis and breast cancer. ( 5 ) Iodine Deficiency Symptoms Clinical signs and symptoms of iodine deficiency include: ( 6 ) Depression Difficulty losing weight Dry skin Headaches [draxe.com]
Symptoms of Lymphatic Congestion Mild skin irritation Sore joints in the morning Cold hands and feet Moderately swollen or sore breasts Mild cellulite Elevated histamine response to environmental irritants Mild headaches Benign cyst formation Accumulated [lifespa.com]
Workup
In the thyroid gland, I-concentration is more progressive, also in the reservoir (from 1% after 30 minutes, to 5.8% after 48 hours, of the total injected dose. [17] The diagnostic workup of a suspected iodine deficiency includes signs and symptoms as [en.wikipedia.org]
Serum
- Abnormal Thyroid Function Test
39 THE THYROID NODULE 374 HORMONE ERNEST L MAZZAFERRI 402 THYROID HORMONE RESISTANCE KENNETH D BURMAN 428 THYROID FUNCTION TESTS 329 and LEONARD WARTOFSKY 440 THYROID SONOGRAPHY COMPUTED and MARTIN 1 SURKS 454 ABNORMAL THYROID FUNCTION TEST 47 THYROID [books.google.com]
Treatment
Abstract A recently described method for the prevention and treatment of endemic iodine deficiency and goiter, introduction of iodine into a public water supply, was tested in Troina, a town of about 13,000 inhabitants in northeast Sicily. [ncbi.nlm.nih.gov]
& Medications Thyrogen Treatment – Thyroid Cancer Thyrogen FAQs Nexavar Treatment – Thyroid Cancer Radioactive Iodine – To Treat the Thyroid Gland Surgery – Hemi Thyroidectomy – Total Thyroidectomy Hyperthyroidism/OveractiveThyroid Hypothyroidism/Underactive [thyroidfoundation.org.au]
Active treatment of goiter is reserved for cases that cause symptoms. If the goiter is small and thyroid function is normal, treatment is not usually offered. [medicalnewstoday.com]
Most Goiters do not need any treatment. Visit your doctor to determine the best treatment for you. Diet-changes: If your goiter is caused by your diet, these suggestions can help you to get enough iodine. [infonet-biovision.org]
Prognosis
Prognosis [ edit ] With iodine supplementation, goiters caused by iodine deficiency decrease in size in very young children and pregnant women. [en.wikipedia.org]
Etiology
Etiology and pathophysiology of Iodine Deficiency Disorders (IDD) Insufficient dietary iodine intake is the most important etiological factor of disorders caused by iodine deficiency, but goitrogens (perchlorates, thiocyanates), physiological periods [intechopen.com]
Dietary supplies of iodine and thiocyanate in the etiology of endemic goitre in Imphal East district of Manipur, north east India. Indian J Med Res 2008;128:601-5. [ PUBMED ] 17. Shankar R, Moorthy D, Pandav CS, Tiwari JS, Karmarkar MG. [thetrp.net]
The role of goitrogenic factors distinct from iodine deficiency in the etiology of goiter [French]. Ann. Endocrinol. (Paris) 49, 302–305 (1988). 72. Glinoer, D. [nature.com]
Epidemiology
Methods: Epidemiological and ecological studies were carried out. Two urban areas were selected from the moderate endemic zones of goiter. [journals.lww.com]
International journal of epidemiology 28: 742–749. View Article Google Scholar 28. [journals.plos.org]
Vanderpump MP (2011) The epidemiology of thyroiddisease. Br Med Bull 99: 39-51. Mansourian AR (2011) A reviewon the metabolicdisorders of iodinedeficiency. Pak J BiolSci 14: 412-424. [omicsonline.org]
Epidemiology of iodine deficiency: salt iodisation and iodine status. Best Pract. Res. Clin. Endocrinol. Metab. 24, 1–11 (2010). 8. UNICEF. Sustainable Elimination of Iodine Deficiency (UNICEF, New York, 2008). 9. [nature.com]
Pathophysiology
[…] goitrogens, such as calcium Gender (higher occurrence in women) Smoking tobacco Alcohol (reduced prevalence in users) Oral contraceptives (reduced prevalence in users) Perchlorates Thiocyanates Age (for different types of iodine deficiency at different ages) Pathophysiology [en.wikipedia.org]
Etiology and pathophysiology of Iodine Deficiency Disorders (IDD) Insufficient dietary iodine intake is the most important etiological factor of disorders caused by iodine deficiency, but goitrogens (perchlorates, thiocyanates), physiological periods [intechopen.com]
Prevention
The high prevalence of goiter among children at the age of 6-12 stressed the need to evaluate the effectiveness of goiter preventive measures in relation with the level of endemicity of the areas and preventive means, applied. [journals.lww.com]
Because ofits effects on brain development, iodinedeficiency is the single most preventable cause of mental retardation in the world. [books.google.com]
The 2012 Revised Nutritional Guidelines for Filipinos (NGF) is urging the use of iodized salt to prevent IDD. [nnc.gov.ph]
The goiter, the size of a small melon, dwarfs Hanmbissa’s thin frame. “ We have to concentrate more on prevention than on surgery ,” Adam said. “ It is a preventable disease .” [tesfanews.net]
Repas is the former chairman of the professional diabetes advisory committees of the Wyoming and the Wisconsin Diabetes Prevention and Control Programs. [healio.com]