Presentation
Therefore, as is also demonstrated in our case, PPCM may present with predominantly non-cardial symptoms. [link.springer.com]
The hand is usually warm, and often a palpable radial pulse or audible Doppler signal is present. [jpgmonline.com]
Visual acuity is reduced, and an afferent pupillary defect is present. The optic disk is swollen and elevated, and the swollen nerve fibers obscure the fine surface vessels of the optic nerve. Often hemorrhages surround the optic disk. [msdmanuals.com]
(See Etiology and Presentation.) [emedicine.medscape.com]
Hematological
- Prolonged Bleeding
bleeding time Lymphoma Bruising susceptibility Leukemia Abnormality of the skeletal system Hypoplasia of the iris Facial paralysis Porencephalic cyst Abnormal thrombocyte morphology Supravalvular aortic stenosis Corneal arcus Xanthelasma Hypercholesterolemia [mendelian.co]
Liver, Gall & Pancreas
- Protein S Deficiency
The relation between arterial thrombosis and the heritable thrombophilias factor V Leiden mutation, prothrombin G20210A mutation, protein C deficiency, protein S deficiency, and antithrombin deficiency are less well established [ 5 ]. [link.springer.com]
Skin
- Subcutaneous Nodule
nodule Abnormal lung morphology Mitral regurgitation Palpitations Thick lower lip vermilion Hypotension Urinary incontinence Abdominal distention Thick vermilion border Thick eyebrow Bulbous nose Stage 5 chronic kidney disease Posteriorly rotated ears [mendelian.co]
Eyes
- Periorbital Fullness
fullness Abnormal mitral valve morphology Abnormality of temperature regulation Decreased glomerular filtration rate Heavy proteinuria Concentric hypertrophic cardiomyopathy Tenesmus Left ventricular septal hypertrophy Tortuosity of conjunctival vessels [mendelian.co]
- Retinal Pigmentation
pigmentation Delusions Anterior hypopituitarism Facial diplegia Nuclear cataract Gangrene Acrocyanosis Myeloid leukemia Prolonged bleeding time Lymphoma Bruising susceptibility Leukemia Abnormality of the skeletal system Hypoplasia of the iris Facial [mendelian.co]
Musculoskeletal
- Numbness of the Feet
Five days before admission she suffered from acute muscle cramps, followed by muscle weakness in both legs and numbness of both feet. [link.springer.com]
Neurotrophic Ulcers With neuropathy being the underlying cause of ulceration, many patients complain of burning, tingling, or numbness of the feet on presentation. [clevelandclinicmeded.com]
- Acroparesthesia
Protruding ear Abnormality of the pinna Mental deterioration Delayed skeletal maturation Apnea EEG abnormality Jaundice Acidosis Autism Cerebral cortical atrophy Diabetes mellitus Hypogonadism Osteoporosis Myoclonus Rod-cone dystrophy Abnormal ST segment Acroparesthesia [mendelian.co]
Psychiatrical
- Psychiatric Manifestation
Other features include endocrinopathy, heart disease, diabetes, hearing loss, and neurological and psychiatric manifestations. [mendelian.co]
- Auditory Hallucination
[…] morphology Delayed speech and language development Hemeralopia Intellectual disability, mild Crohn's disease Abnormality of the cerebellar vermis Psychotic episodes Tubulointerstitial abnormality Renal Fanconi syndrome Abnormal nerve conduction velocity Auditory [mendelian.co]
Neurologic
- Peripheral Neuropathy
Ischemic peripheral neuropathy / V. Ugalde, B.S. Rosen // Phys. Med. Rehabil. Clin. N. Am. — 2001. — V. 12(2). — Р. 365-380. Wilbourn A.J. Ischemic monomelic neuropathy / A.J. Wilbourn, A.J. Furlan, W. Hulley, W. [inj.zaslavsky.com.ua]
Peripheral neuropathy definition and facts Peripheral neuropathy is nerve pain that affects the limbs. Peripheral neuropathy is a condition in which the nerves in the peripheral nervous system become damaged. [medicinenet.com]
Peripheral Neuropathy Prevention Lifestyle choices can play a role in preventing peripheral neuropathy. [hopkinsmedicine.org]
Diagnosis The diagnosis of peripheral neuropathy begins with a neurological examination. [verywellhealth.com]
Home / Conditions / Type 2 Diabetes / Peripheral Neuropathy Associated with CV Disease and Stroke in Type 2 Diabetes Patients Aug 15, 2014 Testing for peripheral neuropathy may provide a way to identify individuals at higher risk of cardiovascular events [diabetesincontrol.com]
- Neuralgia
Gabapentin for the treatment of postherpetic neuralgia: a randomized controlled trial. JAMA 1998; 280: 1837-1842. 58. Rice AS, Maton S. Gabapentin in postherpetic neuralgia: a randomised, double blind, placebo-controlled study. [ge-bu.nl]
(Medical Encyclopedia) Metabolic neuropathies (Medical Encyclopedia) Mononeuritis multiplex (Medical Encyclopedia) Neuralgia (Medical Encyclopedia) Neuropathy secondary to drugs (Medical Encyclopedia) Peripheral neuropathy (Medical Encyclopedia) Radial [icdlist.com]
A prescription patch of 8% capsaicin (Qutenza) is approved for the treatment of postherpetic neuralgia. [medicinenet.com]
Trigeminal neuralgia usually affects only one side of the face. The exact cause of trigeminal neuralgia is unknown, but it develops where the trigeminal nerve is compressed, pinched, or irritated. [physio-pedia.com]
such as the facial pain syndrome trigeminal neuralgia. [neuromodulation.com]
- Clonus
[…] tendon reflexes External ophthalmoplegia Pancreatitis Macular degeneration Migraine with aura Cardiorespiratory arrest Gingival overgrowth Phonophobia Generalized hirsutism EMG abnormality Borderline personality disorder Truncal ataxia Cardiac arrest Clonus [mendelian.co]
- Opisthotonus
[…] acid-base homeostasis Hydrocephalus Exotropia Tetraparesis Renal cyst Cerebral palsy Hemolytic anemia Drooling Intracranial hemorrhage Abnormal pyramidal sign Cortical dysplasia Babinski sign Spasticity Abnormality of bone marrow cell morphology Strabismus Opisthotonus [mendelian.co]
Workup
Workup The proper diagnosis of IMN as a vascular lesion can avoid incorrect classification of the injury as a plexus or a root lesion from trauma, as well as avoid incorrect positioning during surgery. [emedicine.medscape.com]
The diagnostic workup includes: Brain Imaging Head CT without contrast should be performed on all patients to exclude intracranial hemorrhage. [cdemcurriculum.com]
Complete electrodiagnostic studies [Nerve conduction studies (NCS) and needle electromyography (EMG)]: Perform if unclear after initial workup or presence of atypical symptoms: asymmetry, motor predominance, non-length dependence, prominent autonomic [clinicaladvisor.com]
Treatment
Prompt treatment does not restore lost vision in the affected eye but protects the unaffected eye. Inadequate treatment risks relapses and additional vision loss. [msdmanuals.com]
The medicines will usually be tested against another treatment called a control. This will either be a dummy treatment (a placebo) or a standard treatment already in use. [nhs.uk]
Evaluation and treatment of suspected radiculopathy. Figure 3. Evaluation and treatment of suspected radiculopathy. Figure 4. Evaluation and treatment of suspected polyneuropathy (eg, multifocal mononeuropathy). Figure 4. [jaoa.org]
New treatments for hemorrhagic stroke are becoming available and should improve the range of possible treatments. Get more information on new treatments from the Stroke Association. [urmc.rochester.edu]
How many times should the treatment be applied? Follow-up results let us make a conclusion about how well you’re responding to the treatment and whether you can benefit from a second course. [restore-vision.com]
Prognosis
Prognosis can be poor in the case of amyloidosis and the primary vasculitides. The literature is limited to cross-sectional case series and rare longitudinal studies likely related to the incidence of the diseases. [ncbi.nlm.nih.gov]
What You Need to Know There are more than 100 types of peripheral neuropathy, each with its own set of symptoms and prognosis. Peripheral neuropathy has many different causes. [hopkinsmedicine.org]
Visual prognosis tends to be poor. Give corticosteroids if giant cell arteritis is possible. Click here for Patient Education [msdmanuals.com]
What Is the Prognosis for Neuropathy? The outlook for nerve damage depends upon its cause. [emedicinehealth.com]
Prognosis Recent studies have suggested that 40% of patients may experience some degree of improvement in central vision or visual acuity weeks to months after the vision or visual field loss. [lowvision.org]
Etiology
(See Etiology and Presentation.) [emedicine.medscape.com]
Questions exploring different potential etiology’s as well to discriminate between syndromes: Etiologic questions Duration of symptoms (acute versus sub-acute syndromes). [clinicaladvisor.com]
However, muscle cramping may be associated with etiologies other than vascular disease, including neuropathy. [podiatrytoday.com]
They seem to present similar etiologic interactions within the wider group of functional diabetic microangiopathies [ 21 - 23 ]. [omicsonline.org]
Epidemiology
Determination of peripheral neuropathy prevalence and associated factors in Chinese subjects with diabetes and pre-diabetes - ShangHai Diabetic Neuropathy Epidemiology and Molecular Genetics Study (SH-DREAMS). [scielo.br]
Epidemiology of polyneuropathy in diabetes and prediabetes. Handb Clin Neurol 2014; 126:3–22. 10. Said G. Examination and clinical care of the patient with neuropathy. Handb Clin Neurol 2013; 115:235–244. 11. Jensen TS, Finnerup NB. [ekjm.org]
The epidemiology of varicose veins: the Framingham Study. Am J Prev Med. 1988;4(2):96-101. Covidien. Endovenous radiofrequency ablation (RFA) catheter (with 3 cm and 7 cm heating elements) instructions for use. [vasculardiseasemanagement.com]
This has important implications when targeting treatments for NP. [8] Screening questionnaires are suitable for identifying potential patients with neuropathic pain, but further validation of them is needed for epidemiological purposes. [physio-pedia.com]
Pathophysiology
The neurophysiologic changes suggest that the underlying pathophysiology is a distal axonopathy affecting nerve fibers of all sizes. [neurology.org]
The pathophysiologic processes and theories underlying neuropathic pain are multiple. [practicalpainmanagement.com]
Lilly, Pathophysiology of Heart Disease, 2007. [pathophys.org]
I hope future research will help to delineate the pathophysiology of chronic ischaemic neuropathy. [webview.isho.jp]
Prevention
Patients should be instructed to care meticulously for their insensate skin areas in order to prevent skin breakdown. (See Treatment.) [emedicine.medscape.com]
You can help prevent mini strokes and these symptoms by talking to your doctor about risk factors, specifically blood clots, and taking the appropriate preventative measures. Success! Your place in line is confirmed. [intermountainhealthcare.org]
How can anterior ischemic optic neuropathy be prevented? Controlling the risk factors associated with NA-AION is an important preventive measure. [clevelandclinic.org]
Peripheral Neuropathy Prevention Lifestyle choices can play a role in preventing peripheral neuropathy. [hopkinsmedicine.org]